Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Maria K. Storch"'
Autor:
Sarah K Williams, Olaf Maier, Roman Fischer, Richard Fairless, Sonja Hochmeister, Aleksandar Stojic, Lara Pick, Doreen Haar, Sylvia Musiol, Maria K Storch, Klaus Pfizenmaier, Ricarda Diem
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e90117 (2014)
Tumour necrosis factor (TNF) is a proinflammatory cytokine that is known to regulate inflammation in a number of autoimmune diseases, including multiple sclerosis (MS). Although targeting of TNF in models of MS has been successful, the pathological r
Externí odkaz:
https://doaj.org/article/d22907a816ca48d2a37e88deabdc6de2
Autor:
Thomas Seifert-Held, Thomas Pekar, Thomas Gattringer, Nicole E Simmet, Hubert Scharnagl, Christoph Bocksrucker, Christian Lampl, Maria K Storch, Tatjana Stojakovic, Franz Fazekas
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68768 (2013)
BackgroundTo evaluate if plasma levels of midregional pro-adrenomedullin (MR-proADM) improve prediction of functional outcome in ischemic stroke.MethodsIn 168 consecutive ischemic stroke patients, plasma levels of MR-proADM were measured within 24 ho
Externí odkaz:
https://doaj.org/article/b43829b2e50141c1bac2f462fdc5e100
Autor:
Fahmy Aboul-Enein, Thomas Seifert-Held, Simone Mader, Bettina Kuenz, Andreas Lutterotti, Helmut Rauschka, Paulus Rommer, Fritz Leutmezer, Karl Vass, Agathe Flamm-Horak, Robert Stepansky, Wilfried Lang, Elisabeth Fertl, Thomas Schlager, Thomas Heller, Christian Eggers, Georg Safoschnik, Siegrid Fuchs, Jörg Kraus, Hamid Assar, Stefan Guggenberger, Martin Reisz, Peter Schnabl, Martina Komposch, Philipp Simschitz, Alena Skrobal, Alexander Moser, Mario Jeschow, Dorothea Stadlbauer, Manfred Freimüller, Michael Guger, Susanne Schmidegg, Claudia Franta, Vera Weiser, Stefan Koppi, Margret Niederkorn-Duft, Bettina Raber, Iris Schmeissner, Julia Jecel, Alexander Tinchon, Maria K Storch, Markus Reindl, Thomas Berger, Wolfgang Kristoferitsch
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79649 (2013)
BackgroundIn 2008 the Austrian Task Force for Neuromyelitis Optica (NMO) started a nation-wide network for information exchange and multi-centre collaboration. Their aim was to detect all patients with NMO or NMO spectrum disorders (NMO-SD) in Austri
Externí odkaz:
https://doaj.org/article/5efd90c6d18646beb630349dd1ca3dde
Autor:
Simone Mader, Andreas Lutterotti, Franziska Di Pauli, Bettina Kuenz, Kathrin Schanda, Fahmy Aboul-Enein, Michael Khalil, Maria K Storch, Sven Jarius, Wolfgang Kristoferitsch, Thomas Berger, Markus Reindl
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10455 (2010)
BACKGROUND: Neuromyelitis optica (NMO), a severe demyelinating disease, represents itself with optic neuritis and longitudinally extensive transverse myelitis. Serum NMO-IgG autoantibodies (Abs), a specific finding in NMO patients, target the water c
Externí odkaz:
https://doaj.org/article/eda66cbe2e3245a9a9139da90c8fc984
Autor:
Sarah K. Williams, Ricarda Diem, Sonja Hochmeister, Aleksandar Stojic, Richard Fairless, Dorit B. Hoffmann, Frank Schmitz, Maria K. Storch
Publikováno v:
Annals of Neurosciences
Neurodegeneration plays a major role in multiple sclerosis (MS), in which it is thought to be the main determinant of permanent disability. However, the relationship between the immune response and the onset of neurodegeneration is still a matter of
Autor:
Tatjana Stojakovic, Thomas Seifert-Held, Nicole E. Simmet, Thomas Gattringer, Hubert Scharnagl, Franz Fazekas, Maria K. Storch, Thomas Pekar
Publikováno v:
Atherosclerosis. 218:233-237
Previous data suggest that Dickkopf-1 (Dkk-1), an inhibitor of the canonical/β-catenin cascade of the Wnt pathway, is upregulated in carotid atherosclerosis and acute myocardial ischemia. It is currently unclear if such upregulation also occurs in c
Autor:
Martin M. Herrmann, Maria K. Storch, Silvia Barth, Robert Weissert, Karl-Heinz Wiesmüller, Katrien L. de Graaf
Publikováno v:
European Journal of Immunology. 38:299-308
Experimental autoimmune encephalomyelitis (EAE) can be actively induced with the extracellular domain of myelin oligodendrocyte glycoprotein (MOG 1-125). MOG-EAE closely mimics multiple sclerosis (MS) especially as far as demyelination, lesion format
Autor:
Maria K. Storch, Robert Weissert, Balázs Balatoni, Peter Hiestand, Eva-M. Swoboda, Carolyn A. Foster, Agnieszka Koziel, Vinzenz Schönborn, George N. Lambrou
Publikováno v:
Brain Research Bulletin. 74:307-316
FTY720 (fingolimod) is an oral sphingosine 1-phosphate (S1P) receptor modulator under development for the treatment of multiple sclerosis (MS). To elucidate its effects in the central nervous system (CNS), we compared functional parameters of nerve c
Autor:
Abdulmonem Al-Hayani, Reinhard Hohlfeld, Edgar Meinl, Kimberly Hales, Maria K. Storch, David Russell Woolley, Anja Moldenhauer, Stephen N. Davies, Tomas Olsson, Matthew N. Rasband, Kieran R. Williams, Emily K. Mathey, Sviataslau Velhin, Christopher Linington, Tobias Derfuss
Publikováno v:
The Journal of Experimental Medicine
Axonal injury is considered the major cause of disability in patients with multiple sclerosis (MS), but the underlying effector mechanisms are poorly understood. Starting with a proteomics-based approach, we identified neurofascin-specific autoantibo
Publikováno v:
Acta Neuropathologica. 113:195-203
The Notch receptor and its ligands are involved in myelination in central nervous system (CNS) development. Re-expression of this pathway in the adult CNS has been proposed to hamper remyelination in multiple sclerosis. Previous studies also revealed