Upfront primary tumour resection and survival in synchronous metastatic colorectal cancer according to primary tumour location and RAS status: Pooled analysis of the Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD)

Autor: Antonieta Salud, Manuel Valladares-Ayerbes, Javier Sastre, Elena Asensio, Luis Robles, Eduardo Díaz-Rubio, Fernando Rivera, Enrique Aranda, Albert Abad, Auxiliadora Gómez-España, Vicente Alonso-Orduña, Alfredo Carrato, Clara Montagut, Maria Jose Safont, Cristina García González, Manuel Benavides, Encarnación González-Flores, Pilar García-Alfonso, Jose María Vieitez

Publikováno v: European Journal of Surgical Oncology. 48:1123-1132

Retrospective studies and meta-analyses suggest that upfront primary tumour resection (UPTR) confers a survival benefit in patients with asymptomatic unresectable metastatic colorectal cancer (mCRC) undergoing chemotherapy, however a consensus of its

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecbf9e4a4e449540292ffcb4f5803e5e
https://doi.org/10.1016/j.ejso.2021.11.122

Evolution of

Autor: Manuel, Valladares-Ayerbes, Pilar, Garcia-Alfonso, Jorge, Muñoz Luengo, Paola Patricia, Pimentel Caceres, Oscar Alfredo, Castillo Trujillo, Rosario, Vidal-Tocino, Marta, Llanos, Beatriz, Llorente Ayala, Maria Luisa, Limon Miron, Antonieta, Salud, Luis, Cirera Nogueras, Rocio, Garcia-Carbonero, Maria Jose, Safont, Esther, Falco Ferrer, Jorge, Aparicio, Maria Angeles, Vicente Conesa, Carmen, Guillén-Ponce, Paula, Garcia-Teijido, Maria Begoña, Medina Magan, Isabel, Busquier, Mercedes, Salgado, Ariadna, Lloansí Vila

Publikováno v: Cancers. 14(24)

The serial analysis of cell-free DNA (cfDNA) enables minimally invasive monitoring of tumor evolution, providing continuous genetic information. PERSEIDA was an observational, prospective study assessing the cfDNA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d74bf849bbe7622665596f882d02968a
https://pubmed.ncbi.nlm.nih.gov/36551560

Controversies in the treatment of RAS wild-type metastatic colorectal cancer

Autor: R. Vera, E. Élez, E. González, M. Salgado, Maria Jose Safont, Enrique Aranda, Jesús Gallego

Publikováno v: CLINICAL & TRANSLATIONAL ONCOLOGY
r-FIHGUV. Repositorio Institucional de Producción Científica de la Fundación de Investigación del Hospital General de Valencia
instname
Clinical & Translational Oncology
r-FISABIO. Repositorio Institucional de Producción Científica
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)

Objective To provide guidance for the management of RAS wild-type (wt) metastatic colorectal cancer (mCRC) in daily practice. Methods Nominal group and Delphi techniques were used. A steering committee of seven experts analyzed the current management

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07511d8be45cb61e3c7d4f8c29d93097
https://link.springer.com/content/pdf/10.1007/s12094-020-02475-8.pdf

Clinicopathological and Molecular Characterization of Metastatic Gastrointestinal Stromal Tumors with Prolonged Benefit to Frontline Imatinib

Autor: Ana Vivancos, Javier Hernández-Losa, Xavier Garcia-del-Muro, Nadia Hindi, Joan Carles, Maria Jose Safont, Anna Estival, Jose Duran, Jordi Rubió-Casadevall, Laura Jiménez, Aránzazu Manzano, Stefania Landolfi, David Vicente‐Baz, Javier Lavernia, Ana Sebio, Roberto Diaz-Beveridge, Carles Pericay, Isabel Pajares, Virginia Martínez-Marín, Joaquín Arribas, Claudia Valverde, César Serrano

Publikováno v: Oncologist
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
ONCOLOGIST
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
r-FIHGUV. Repositorio Institucional de Producción Científica de la Fundación de Investigación del Hospital General de Valencia
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid

Background Oncogenic KIT/PDGFRA signaling inhibition with imatinib achieves disease control in most patients with advanced/metastatic gastrointestinal stromal tumor (GIST), but resistance eventually develops after 20-24 months. Notably, a small subse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::523dc45abe56d4e6715b02e7023e6832
https://fundanet.iislafe.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=10236

Is burn-out-syndrome a problem among oncology workers? Incidence and effective tools to achieve improvement

Autor: Ana Gómez, Carlos Camps, Vega Iranzo, Cristina Caballero, I. Shaheen, Maria Jose Godes, Marina Meri Abad, Ana Blasco, Mireia Gil Raga, Miriam Lobo de Mena, I. Ortega, Maria Jose Safont Aguilera, Martín Núñez Abad, Francisco Aparisi, Alberto Jacobo Cunquero Tomas, Amaya Belen Fernandez Diaz, María del Rocío Ramirez Belloch, Milagros Franco de la Rosa, Alfonso Berrocal

Publikováno v: Journal of Clinical Oncology. 38:11016-11016

11016 Background: Burn-Out Syndrome (BOS) is defined by (1) emotional and physical exhaustion; (2) cynicism and depersonalization; and (3) no personal nor professional fulfillment. It affects up to 78% of oncology-related workers (doctors, nurses and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::23c440758d88aba416180edc54950879
https://doi.org/10.1200/jco.2020.38.15_suppl.11016