Leishmanicidal activity and cytotoxicity of compounds from two Annonacea species cultivated in Northeastern Brazil

Autor: Nadja Soares Vila-Nova, Selen Maia de Morais, Maria José Cajazeiras Falcão, Lyeghyna Karla Andrade Machado, Cláudia Maria Leal Beviláqua, Igor Rafael Sousa Costa, Nilce Viana Gramosa Pompeu de Sousa Brasil, Heitor Franco de Andrade Júnior

Publikováno v: Revista da Sociedade Brasileira de Medicina Tropical, Vol 44, Iss 5, Pp 567-571 (2011)

INTRODUCTION: Visceral leishmaniasis is endemic in 88 countries, with a total of 12 million people infected and 350 million at risk. In the search for new leishmanicidal agents, alkaloids and acetogenins isolated from leaves of Annona squamosa and se

Externí odkaz: https://doaj.org/article/90a6b09c235a4e80bca2497867876e05

Chemical Composition and Antifungal In Vitro and In Silico, Antioxidant, and Anticholinesterase Activities of Extracts and Constituents of Ouratea fieldingiana (DC.) Baill

Autor: Selene Maia de Morais, José Eranildo Teles do Nascimento, Ana Livya Moreira Rodrigues, Daniele Silva de Lisboa, Raimundo Braz Filho, Maria José Cajazeiras Falcão, Hortência Ribeiro Liberato, Daniela Ribeiro Alves, Cecília Rocha da Silva, Hélio Vitoriano Nobre Júnior, Valdir Ferreira de Paula Junior

Publikováno v: Evidence-Based Complementary and Alternative Medicine, Vol 2018 (2018)
Repositório Institucional da Universidade Federal do Ceará (UFC)
Universidade Federal do Ceará (UFC)
instacron:UFC
Evidence-based Complementary and Alternative Medicine : eCAM

Ouratea fieldingiana(Gardner) Engl is popularly used for wound healing. This study describes the main chemical compounds present in extracts ofO. fieldingianaand evaluates their biological potential by investigating antifungal, antioxidant, and antic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99e4014c3db12b8429e2cbc4a9ce58e6

Induction of apoptosis by pterocarpans from Platymiscium floribundum in HL-60 human leukemia cells

Autor: Edilberto R. Silveira, Letícia V. Costa-Lotufo, Maria José Cajazeiras Falcão, Thais Martins de Lima, Manoel Odorico de Moraes, Ivana N. F. Dantas, Rui Curi, Gardênia C. G. Militão, Cláudia Pessoa, Mary Anne S. Lima

Publikováno v: Life Sciences. 78:2409-2417

(+)-2,3,9-Trimethoxy-pterocarpan (1) (+)-3,9-dimethoxy-pterocarpan [(+)-homopterocarpin] (2), (+)-3-hydroxy-9-methoxy-pterocarpan [(+)-medicarpin] (3) and (+)-3,4-dihydroxy-9-methoxy-pterocarpan [(+)-vesticarpan] (4) are cytotoxic pterocarpans isolat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d68d97924b09a1ce9a15b7f5820a9fa
https://doi.org/10.1016/j.lfs.2005.09.044

Activity of cycloartane-type triterpenes and sterols isolated from Musa paradisiaca fruit peel against Leishmania infantum chagasi

Autor: Heitor Franco de Andrade-Júnior, Adriana A. Silva, Maria José Cajazeiras Falcão, Selene Maia de Morais, Francisco Stefânio Barreto, R. P. A. Cardoso, Ícaro Gusmão Pinto Vieira, S.M. Viana, Maria Jania Teixeira, L.M. Ribeiro, Camila Aparecida de Carvalho

Publikováno v: Phytomedicine : international journal of phytotherapy and phytopharmacology. 21(11)

The aim of the study was to evaluate in vitro the antileishmanial activity of triterpenes and sterols isolated from Musa paradisiaca (banana) fruit peel used traditionally to treat leishmaniasis. The compounds were isolated from the ethanolic extract

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3e936f70103da9165840b27f5cae850
https://pubmed.ncbi.nlm.nih.gov/24916706

Leishmanicidal and cholinesterase inhibiting activities of phenolic compounds of Dimorphandra gardneriana and Platymiscium floribundum, native plants from Caatinga biome

Autor: Ícaro Gusmão Pinto Vieira, Maria José Cajazeiras Falcão, Claudia Maria Leal Bevilaqua, Mary E. Wilson, Heitor Franco de Andrade, Nadja S. Vila-Nova, Fernanda Cristina Macedo Rondon, Selene Maia de Morais

Publikováno v: Pesquisa Veterinária Brasileira, Volume: 32, Issue: 11, Pages: 1164-1168, Published: NOV 2012
ResearcherID
Pesquisa Veterinária Brasileira, Vol 32, Iss 11, Pp 1164-1168 (2012)
Pesquisa Veterinária Brasileira v.32 n.11 2012
Pesquisa Veterinária Brasileira
Colégio Brasileiro de Patologia Animal (CBPA)
instacron:EMBRAPA

In recent years, the Brazilian Health Ministry and the World Health Organization have supported research into new technologies that may contribute to the surveillance, new treatments, and control of visceral leishmaniasis within the country. In light

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ccb6d03e9fcc22e211f562d7b73617f
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-736X2012001100015&lng=en&tlng=en