Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Maria João Amorim"'
Publikováno v:
Acta Médica Portuguesa, Vol 37, Iss 9 (2024)
N/a.
Externí odkaz:
https://doaj.org/article/2c3fe788c11d4f25a7c1e456e50bac0d
Autor:
Mariana Marques, Bruno Ramos, Hélio Albuquerque, Marisa Pereira, Diana Roberta Ribeiro, Alexandre Nunes, Jéssica Sarabando, Daniela Brás, Ana Rita Ferreira, Rui Vitorino, Maria João Amorim, Artur M.S. Silva, Ana Raquel Soares, Daniela Ribeiro
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109100- (2024)
Summary: Influenza A virus (IAV) employs multiple strategies to manipulate cellular mechanisms and support proper virion formation and propagation. In this study, we performed a detailed analysis of the interplay between IAV and the host cells’ pro
Externí odkaz:
https://doaj.org/article/cccbb66ab8b64f5c84b861d2d41ef013
CD8+ tissue-resident memory T-cell development depends on infection-matching regulatory T-cell types
Autor:
Leandro Barros, Daryna Piontkivska, Patrícia Figueiredo-Campos, Júlia Fanczal, Sofia Pereira Ribeiro, Marta Baptista, Silvia Ariotti, Nuno Santos, Maria João Amorim, Cristina Silva Pereira, Marc Veldhoen, Cristina Ferreira
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Immunological memory is critical for immune protection, particularly at epithelial sites, which are under constant risk of pathogen invasions. To counter invading pathogens, CD8+ memory T cells develop at the location of infection: tissue-re
Externí odkaz:
https://doaj.org/article/43acb929177344ada2f0bf5d1657f9b6
Autor:
Sílvia Vale-Costa, Temitope Akhigbe Etibor, Daniela Brás, Ana Laura Sousa, Mariana Ferreira, Gabriel G Martins, Victor Hugo Mello, Maria João Amorim
Publikováno v:
PLoS Biology, Vol 21, Iss 11, p e3002290 (2023)
It is now established that many viruses that threaten public health establish condensates via phase transitions to complete their lifecycles, and knowledge on such processes may offer new strategies for antiviral therapy. In the case of influenza A v
Externí odkaz:
https://doaj.org/article/30fef2fdbff74e1ebed2f18c41744806
Autor:
Juliana Gonçalves, Magda Melro, Marta Alenquer, Catarina Araújo, Júlia Castro-Neves, Daniela Amaral-Silva, Filipe Ferreira, José S. Ramalho, Nádia Charepe, Fátima Serrano, Carlos Pontinha, Maria João Amorim, Helena Soares
Publikováno v:
JCI Insight, Vol 8, Iss 17 (2023)
The intricate interplay between maternal immune response to SARS-CoV-2 and the transfer of protective factors to the fetus remains unclear. By analyzing mother-neonate dyads from second and third trimester SARS-CoV-2 infections, our study shows that
Externí odkaz:
https://doaj.org/article/27cf36963774436090169e9a960d2b16
Autor:
Temitope Akhigbe Etibor, Aidan O’Riain, Marta Alenquer, Christian Diwo, Sílvia Vale-Costa, Maria João Amorim
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 20, p 15253 (2023)
Biomolecular condensates are crucial compartments within cells, relying on their material properties for function. They form and persist through weak, transient interactions, often undetectable by classical biochemical approaches. Hence, microscopy-b
Externí odkaz:
https://doaj.org/article/3aa0ec50ffb640e4bb0c76e37736430e
Autor:
Marta Alenquer, Tiago Milheiro Silva, Onome Akpogheneta, Filipe Ferreira, Sílvia Vale-Costa, Mónica Medina-Lopes, Frederico Batista, Ana Margarida Garcia, Vasco M. Barreto, Cathy Paulino, João Costa, João Sobral, Maria Diniz-da-Costa, Susana Ladeiro, Rita Corte-Real, José Delgado Alves, Ricardo B. Leite, Jocelyne Demengeot, Maria João Rocha Brito, Maria João Amorim
Publikováno v:
PLoS ONE, Vol 17, Iss 6 (2022)
Background Adults are being vaccinated against SARS-CoV-2 worldwide, but the longitudinal protection of these vaccines is uncertain, given the ongoing appearance of SARS-CoV-2 variants. Children remain largely unvaccinated and are susceptible to infe
Externí odkaz:
https://doaj.org/article/90766476328c4808b91b52d1807d82f0
Autor:
Cruz S. Sebastião, Adis Cogle, Alice D’Alva Teixeira, Ana Micolo Cândido, Chissengo Tchoni, Maria João Amorim, N’gueza Loureiro, Paolo Parimbelli, Carlos Penha-Gonçalves, Jocelyne Demengeot, Euclides Sacomboio, Manuela Mendes, Margarete Arrais, Joana Morais, Jocelyne Neto de Vasconcelos, Miguel Brito
Publikováno v:
Tropical Medicine and Infectious Disease, Vol 7, Iss 11, p 338 (2022)
Background: Infection due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is associated with clinical features of diverse severity. Few studies investigated the severity and mortality predictors of coronavirus disease 2019 (COVID-19)
Externí odkaz:
https://doaj.org/article/4dd96b1c03614cc1a36c238ddb39c41f
Autor:
Marta Alenquer, Filipe Ferreira, Diana Lousa, Mariana Valério, Mónica Medina-Lopes, Marie-Louise Bergman, Juliana Gonçalves, Jocelyne Demengeot, Ricardo B. Leite, Jingtao Lilue, Zemin Ning, Carlos Penha-Gonçalves, Helena Soares, Cláudio M. Soares, Maria João Amorim
Publikováno v:
PLoS Pathogens, Vol 17, Iss 8 (2021)
Understanding SARS-CoV-2 evolution and host immunity is critical to control COVID-19 pandemics. At the core is an arms-race between SARS-CoV-2 antibody and angiotensin-converting enzyme 2 (ACE2) recognition, a function of the viral protein spike. Mut
Externí odkaz:
https://doaj.org/article/e0fcf74913e6441bbcba7b8241d921b4
Autor:
Nuno Brito Santos, Zoé Enderlin Vaz da Silva, Catarina Gomes, Celso A Reis, Maria João Amorim
Publikováno v:
PLoS Pathogens, Vol 17, Iss 7, p e1009381 (2021)
Clearance of viral infections, such as SARS-CoV-2 and influenza A virus (IAV), must be fine-tuned to eliminate the pathogen without causing immunopathology. As such, an aggressive initial innate immune response favors the host in contrast to a detrim
Externí odkaz:
https://doaj.org/article/526c994aa22a4396acc639f63657c52a