Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Maria Jesús Fernández-Aceñero"'
Autor:
Sonia Solanes-Casado, Arancha Cebrián, María Rodríguez-Remírez, Ignacio Mahíllo, Laura García-García, Anxo Río-Vilariño, Natalia Baños, Guillermo de Cárcer, Ana Monfort-Vengut, Víctor Castellano, Maria Jesús Fernández-Aceñero, Jesús García-Foncillas, Laura del Puerto-Nevado
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 144, Iss , Pp 112347- (2021)
New therapeutic targets are revolutionizing colorectal cancer clinical management, opening new horizons in metastatic patients’ outcome. Polo Like Kinase1 (PLK1) inhibitors have high potential as antitumoral agents, however, the emergence of drug r
Externí odkaz:
https://doaj.org/article/7e7044e51a4443f1bd9c0e6e88deaf7a
Autor:
Aiora Cenigaonandia‐Campillo, Ana Garcia‐Bautista, Anxo Rio‐Vilariño, Arancha Cebrian, Laura delPuerto, José Antonio Pellicer, José Antonio Gabaldón, Horacio Pérez‐Sánchez, Miguel Carmena‐Bargueño, Carolina Meroño, Javier Traba, María Jesús Fernandez‐Aceñero, Natalia Baños‐Herraiz, Lorena Mozas‐Vivar, Estrella Núñez‐Delicado, Jesús Garcia‐Foncillas, Óscar Aguilera
Publikováno v:
Molecular Oncology, Vol 18, Iss 9, Pp 2212-2233 (2024)
In pancreatic ductal adenocarcinoma (PDAC), metabolic rewiring and resistance to standard therapy are closely associated. PDAC cells show enormous requirements for glucose‐derived citrate, the first rate‐limiting metabolite in the synthesis of ne
Externí odkaz:
https://doaj.org/article/15680545600940349d1f3088fd3a5d0b
Autor:
Rubén A. Bartolomé, Laura Pintado-Berninches, Ángela Martín-Regalado, Javier Robles, Tania Calvo-López, Marina Ortega-Zapero, Celia Llorente-Sáez, Issam Boukich, María Jesús Fernandez-Aceñero, J. Ignacio Casal
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-17 (2024)
Abstract Background Cadherin-17 (CDH17), a marker of differentiation in intestinal cells, binds and activates α2β1 integrin to promote cell adhesion and proliferation in colorectal cancer (CRC) metastasis. Furthermore, CDH17 associates with p120- a
Externí odkaz:
https://doaj.org/article/c966be1e7f0f4d22a3aa627c32f73981
Autor:
José Manuel García-Martínez, Ana Chocarro-Calvo, Javier Martínez-Useros, María Jesús Fernández-Aceñero, M Carmen Fiuza, José Cáceres-Rentero, Antonio De la Vieja, Antonio Barbáchano, Alberto Muñoz, María Jesús Larriba, Custodia García-Jiménez
Publikováno v:
eLife, Vol 12 (2023)
Posttranslational modifications of epigenetic modifiers provide a flexible and timely mechanism for rapid adaptations to the dynamic environment of cancer cells. SIRT1 is an NAD+-dependent epigenetic modifier whose activity is classically associated
Externí odkaz:
https://doaj.org/article/f3a455fa9b724e539e76a6e968190b0d
Autor:
Javier Robles, Laura Pintado‐Berninches, Issam Boukich, Beatriz Escudero, Vivian de losRios, Rubén A Bartolomé, Marta Jaén, Ángela Martín‐Regalado, María Jesús Fernandez‐Aceñero, Juan Ignacio Imbaud, José Ignacio Casal
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 8, Iss 6, Pp 495-508 (2022)
Abstract The necessity to accurately predict recurrence and clinical outcome in early stage colorectal cancer (CRC) is critical to identify those patients who may benefit from adjuvant chemotherapy. Here, we developed and validated a gene‐based ris
Externí odkaz:
https://doaj.org/article/b7b96c02512a43f4b84ef71ae7a7c2d1
Autor:
María Garranzo‐Asensio, Javier Rodríguez‐Cobos, Coral San Millán, Carmen Poves, María Jesús Fernández‐Aceñero, Daniel Pastor‐Morate, David Viñal, Ana Montero‐Calle, Guillermo Solís‐Fernández, María‐Ángeles Ceron, Manuel Gámez‐Chiachio, Nuria Rodríguez, Ana Guzmán‐Aránguez, Rodrigo Barderas, Gemma Domínguez
Publikováno v:
Molecular Oncology, Vol 16, Iss 14, Pp 2672-2692 (2022)
Colorectal cancer (CRC) is the third most common cancer and the second leading cause of cancer‐related death worldwide. Alterations in proteins of the p53‐family are a common event in CRC. ΔNp73, a p53‐family member, shows oncogenic properties
Externí odkaz:
https://doaj.org/article/234f5c92fcf7483793358afcfa781355
Autor:
Ana Montero-Calle, Sofía Jiménez de Ocaña, Ruth Benavente-Naranjo, Raquel Rejas-González, Rubén A. Bartolomé, Javier Martínez-Useros, Rodrigo Sanz, Jana Dziaková, María Jesús Fernández-Aceñero, Marta Mendiola, José Ignacio Casal, Alberto Peláez-García, Rodrigo Barderas
Publikováno v:
Cells, Vol 12, Iss 21, p 2548 (2023)
SPRY domain-containing protein 7 (SPRYD7) is a barely known protein identified via spatial proteomics as being upregulated in highly metastatic-to-liver KM12SM colorectal cancer (CRC) cells in comparison to its isogenic poorly metastatic KM12C CRC ce
Externí odkaz:
https://doaj.org/article/4ba87d93cedc4013968dcac0ed1737bc
Autor:
Carlos Lacalle-Gonzalez, Maria Florez-Cespedes, Lara Sanz-Criado, Michael Ochieng’ Otieno, Edurne Ramos-Muñoz, Maria Jesus Fernandez-Aceñero, Luis Ortega-Medina, Jesus Garcia-Foncillas, Javier Martinez-Useros
Publikováno v:
Biomedicines, Vol 11, Iss 10, p 2812 (2023)
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive neoplasm with very poor patient survival outcomes despite available treatments. There is an urgent need for new potential treatment options and novel biomarkers for these patients. Delta-like c
Externí odkaz:
https://doaj.org/article/2d55f38ea8944f848534712b13302ea6
Autor:
Ana Montero-Calle, Itziar Aranguren-Abeigon, María Garranzo-Asensio, Carmen Poves, María Jesús Fernández-Aceñero, Javier Martínez-Useros, Rodrigo Sanz, Jana Dziaková, Javier Rodriguez-Cobos, Guillermo Solís-Fernández, Eloy Povedano, Maria Gamella, Rebeca Magnolia Torrente-Rodríguez, Miren Alonso-Navarro, Vivian de los Ríos, J. Ignacio Casal, Gemma Domínguez, Ana Guzman-Aranguez, Alberto Peláez-García, José Manuel Pingarrón, Susana Campuzano, Rodrigo Barderas
Publikováno v:
Engineering, Vol 7, Iss 10, Pp 1393-1412 (2021)
Colorectal cancer (CRC) is the second leading cause of cancer-related death worldwide. The five-year survival rate of CRC patients depends on the stage at diagnosis, being higher than 80% when CRC is diagnosed in the early stages but lower than 10% w
Externí odkaz:
https://doaj.org/article/37d8fc52650e413c80d384b5a7c4075f
Autor:
Ana Montero-Calle, Marta Gómez de Cedrón, Adriana Quijada-Freire, Guillermo Solís-Fernández, Victoria López-Alonso, Isabel Espinosa-Salinas, Alberto Peláez-García, María Jesús Fernández-Aceñero, Ana Ramírez de Molina, Rodrigo Barderas
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Approximately 25% of colorectal cancer (CRC) patients experience systemic metastases, with the most frequent target organs being the liver and lung. Metabolic reprogramming has been recognized as one of the hallmarks of cancer. Here, metabolic and fu
Externí odkaz:
https://doaj.org/article/050b971bb1f84d0ca089a7952ddb0af1