Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Maria J. Vidal"'
Autor:
Benedetta Conte, Fara Brasó-Maristany, Adela Rodríguez Hernández, Tomás Pascual, Guillermo Villacampa, Francesco Schettini, Maria J. Vidal Losada, Elia Seguí, Laura Angelats, Isabel Garcia-Fructuoso, Raquel Gómez-Bravo, Natàlia Lorman-Carbó, Laia Paré, Mercedes Marín-Aguilera, Olga Martínez-Sáez, Barbara Adamo, Esther Sanfeliu, Beatrice Fratini, Claudette Falato, Núria Chic, Ana Vivancos, Patricia Villagrasa, Johan Staaf, Joel S. Parker, Charles M. Perou, Aleix Prat
Publikováno v:
EBioMedicine, Vol 102, Iss , Pp 105043- (2024)
Summary: Background: Early-stage triple-negative breast cancer (TNBC) displays clinical and biological diversity. From a biological standpoint, immune infiltration plays a crucial role in TNBC prognosis. Currently, there is a lack of genomic tools ai
Externí odkaz:
https://doaj.org/article/e280cec22ed2498189d321ebd159a946
Autor:
Tomás Pascual, Mafalda Oliveira, Eva Ciruelos, Meritxell Bellet Ezquerra, Cristina Saura, Joaquin Gavilá, Sonia Pernas, Montserrat Muñoz, Maria J. Vidal, Mireia Margelí Vila, Juan M. Cejalvo, Blanca González-Farré, Martin Espinosa-Bravo, Josefina Cruz, Francisco Javier Salvador-Bofill, Juan Antonio Guerra, Ana María Luna Barrera, Miriam Arumi de Dios, Stephen Esker, Pang-Dian Fan, Olga Martínez-Sáez, Guillermo Villacampa, Laia Paré, Juan M. Ferrero-Cafiero, Patricia Villagrasa, Aleix Prat
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Background: Preclinical data support a key role for the human epidermal growth factor receptor 3 (HER3) pathway in hormone receptor (HR)–positive breast cancer. Recently, new HER3 directed antibody drug conjugates have shown activity in breast canc
Externí odkaz:
https://doaj.org/article/0fe8923a3c164bc1a60918d97253ce3e
Akademický článek
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Autor:
Aleix Prat, Juan M. Cejalvo, Laia Pare, Olga Martínez-Sáez, Mireia Margelí Vila, Claudette Falato, Josefina Cruz, Miriam Arumí de Dios, Maria J Vidal, Juan Antonio Guerra, Ana Maria Luna Barrera, Pablo Tolosa, Francisco Javier Salvador-Bofill, Sonia Pernas, Blanca Gonzáles-Farré, Esther Sanfeliu, Eva Ciruelos, Violeta Serra, Martin Espinosa-Bravo, Yann Izarzugaza, Stephen Esker, Pang-Dian Fan, Guillermo Villacampa, Juan M Ferrero-Cafiero, Tomás Pascual, Mafalda Oliveira
Publikováno v:
Cancer Research. 82:PD13-04
Introduction Patritumab deruxtecan (U3-1402; HER3-DXd) is a HER3-directed antibody drug conjugate with demonstrated clinically meaningful antitumor activity and acceptable safety profile in heavily pre-treated metastatic breast cancer (BC) with high
Autor:
Fabio Pellegatta, Daniela Pomes, Maria J. Vidal, Laura Galli, Giuseppina Belotti, Carlo Meloni, Giuseppe Pizzetti, Sergio Chierchia, Mauro Carlino, Yan Lu, Antonella Radaelli
Publikováno v:
Journal of Cardiovascular Pharmacology. 30:455-460
Previous studies have shown that adhesion molecules play a crucial role in leukocyte-endothelium interactions that occur during myocardial ischemia and reperfusion. We assessed the plasma levels of the soluble form of E-selectin (sE-selectin) and int
Autor:
Fabio Pellegatta, Marco R. Sonia, Luca Benatti, Maria J. Vidal, Roberta Tagliabue, Antonella Isacchi, Jennifer S. Pollock, Lucia Monaco, Sergio Chierchia, Yan Lu
Publikováno v:
Endothelium. 2:125-137
Transformed endothelial cells expressing the polyoma middle T oncogene (endothelioma cells) cause tumors in mice and recruit host endothelial cells without stimulating their proliferation. A role for the endothelial vasoactive mediators nitric oxide
Autor:
Chantal M. Boulanger, Jean Vivien Mombouli, Paul M. Vanhoutte, Ghislaine A. Joly, Maria J. Vidal
Publikováno v:
Journal of Cardiovascular Pharmacology. 23:S1-5
Experiments were designed to study the effects of trandolaprilat on endothelium-dependent responses in isolated blood vessels. Rings of either femoral or left circumflex coronary arteries of the dog or thoracic aortas of normotensive rats were suspen
Autor:
C. Boulanger, T. Nagao, Maria J. Vidal, Paul M. Vanhoutte, Jean-Vivien Mombouli, Stephane Illiano
Publikováno v:
Journal of Cardiovascular Pharmacology. 22:S10-S16
Angiotensin-converting enzyme (ACE) inhibitors were designed to prevent the vasoconstrictor influence of the activated renin-angiotensin system. However, it has long been suspected that the vasodilator actions of these compounds are not entirely rela
Publikováno v:
Fundamental & Clinical Pharmacology. 5:503-511
Summary— The role of nitric oxide (NO) in the genesis of motor and electrocortical seizures elicited by administration of excitatory amino acid agonists into the deep prepiriform cortex (DPC) has been evaluated. Motor and electrocortical seizures o
Publikováno v:
Journal of Cardiovascular Pharmacology. 17:S269-S272
The purpose of the present investigations was to test the possible involvement of nitric oxide (NO) in glutamate-induced baroreceptor reflex-like responses in the rat nucleus tractus solitarius (NTS). Anesthetized normotensive rats were prepared for