Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Maria J. Crowe"'
Publikováno v:
Cellular Reprogramming. 13:385-390
Recent studies suggest that cellular therapies that utilize mesenchymal stem cells (MSCs), especially ones that have been neurally induced (NI), may provide a functional benefit in a wide range of neurological disorders. Recently, we developed a new
Autor:
Maria J. Crowe, Thomas A. Gennarelli, Ronald J. Fijalkowski, Brian D. Stemper, Narayan Yoganandan, Frank A. Pintar
Publikováno v:
Journal of Neurotrauma. 24:1387-1398
A new experimental model was developed to induce diffuse brain injury (DBI) in rats through pure coronal plane angular acceleration. An impactor was propelled down a guide tube toward the lateral extension of the helmet fixture. Upon impactor-helmet
Autor:
Maria J. Crowe, Michael A. Pizzi
Publikováno v:
Journal of Neurotrauma. 23:1750-1765
Growth-inhibitory chondroitin sulfate proteoglycans (CSPGs) are upregulated during glial scar formation at the site of spinal cord injury (SCI) in adult mammals. This CSPG-containing glial scar inhibits axonal regeneration. Matrix metalloproteinases
Autor:
Arshak R. Alexanian, Shekar N. Kurpad, Maria J. Crowe, Melissa Y. Macias, Mara B. Syring, Michael A. Pizzi
Publikováno v:
Experimental Neurology. 201:335-348
Transplantation of neural stem cells (NSCs) in the injured spinal cord has been shown to improve functional outcome; however, recent evidence has demonstrated forelimb allodynia following transplantation of embryonic NSCs. The aim of this study was t
Autor:
Dennis J. Maiman, Zhong-Ping Sun, Joseph H. Battocletti, Maria J. Crowe, Melissa Y. Macias, Frank A. Pintar
Publikováno v:
Spine. 28:2660-2666
STUDY DESIGN Animal model study of eight healthy commercial cats was conducted. OBJECTIVE To determine whether pulsed electromagnetic field (PMF) stimulation results in improvement of function after contusive spinal cord injury in cats. SUMMARY OF BA
Publikováno v:
Journal of Investigative Dermatology. 115(1):3-11
Previous studies showed that full-thickness wounds in transforming growth factor-beta1-deficient mice initially heal normally. Unfortunately, transforming growth factor-beta1 deficiency leads to a multifocal inflammatory disease affecting most organs
Autor:
Jeffery N. Masters, Maria J. Crowe, Sheri L. Shuman, Michael S. Beattie, Jacqueline C. Bresnahan
Publikováno v:
Nature Medicine. 3:73-76
Apoptosis is a morphologically defined form of programmed cell death seen in a variety of circumstances, including immune cell selection, carcinogenesis and development. Apoptosis has very recently been seen after ischemic or traumatic injury to the
Publikováno v:
Cytotherapy. 13(1)
Traumatic injuries of the central nervous system cause damage and degeneration of specific cell populations with subsequent functional loss. Cell transplantation is a strategy to treat such injuries by replacing lost or damaged cell populations. Many
Autor:
Sarah K. Pixley, Maria J. Crowe
Publikováno v:
Brain Research. 538:147-151
A monoclonal antibody directed against the synthetic enzyme for the dipeptide carnosine was used on cryostat sections of olfactory epithelium from the glass frog Rana pipiens . A subpopulation of what morphologically resembled olfactory receptor neur
Autor:
Michael A. Pizzi, Maria J. Crowe
Publikováno v:
Experimental neurology. 204(2)
After an injury to the adult mammalian central nervous system (CNS), a variety of growth-inhibitory molecules are upregulated. A glial scar forms at the site of injury and is composed of numerous molecular substances, including chondroitin sulfate pr