Thrombospondin-1/CD47 Interaction Regulates Th17 and Treg Differentiation in Psoriasis

Autor: Pedro Rodríguez-Jiménez, Pablo Chicharro, Mar Llamas-Velasco, Danay Cibrian, Laura Trigo-Torres, Alicia Vara, María Jiménez-Fernández, Javier Sevilla-Montero, Maria J. Calzada, Francisco Sánchez-Madrid, Hortensia de la Fuente, Esteban Daudén

Publikováno v: Frontiers in Immunology, Vol 10 (2019)

Accumulating evidence on the role of Thrombospondin-1 (TSP-1) in the immune response has emerged during the last years. In spite of the importance of TSP-1 not only as anti-angiogenic factor but also as an immunomodulatory molecule, studies on the ro

Externí odkaz: https://doaj.org/article/a69ea39b157645c59115411f843a3a2a

COVID-19 severity associates with pulmonary redistribution of CD1c+ DCs and inflammatory transitional and nonclassical monocytes

Autor: Hortensia de la Fuente, Pedro Martínez-Fleta, Ignacio Santos, Ana Alcaraz-Serna, Elena Ávalos, Ana Marcos-Jimenez, Arantzazu Alfranca, Beatriz Aldave, Ana Sanchez-Azofra, Ildefonso Sánchez-Cerrillo, Isidoro González-Álvaro, Luciana del Campo Guerola, Tamara Mateu-Albero, Pedro Landete, Maria J. Calzada, Santiago Sánchez-Alonso, Francisco Sánchez-Madrid, Enrique Martín-Gayo, Ligia Gabrie, Laura Esparcia, Joan B. Soriano, Celia López-Sanz, Cecilia Muñoz-Calleja, Julio Ancochea

Publikováno v: Journal of Clinical Investigation. 130:6290-6300

SARS-CoV-2 is responsible for the development of coronavirus disease 2019 (COVID-19) in infected individuals, who can either exhibit mild symptoms or progress toward a life-threatening acute respiratory distress syndrome (ARDS). Exacerbated inflammat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::349d452f6d6fa977086f35e42ddc5c19
https://doi.org/10.1172/jci140335

Time-dependent dual effect of NLRP3 inflammasome in brain ischemia

Autor: Luis Monge, Ana I. Casas, Alejandra Palomino-Antolín, Javier Egea, Molecular Neuroinflammation, Celine Decouty-Pérez, Nuria Fernández, Javier Sevilla-Montero, Paloma Narros-Fernández, Ana Belen Lopez-Rodriguez, Víctor Farré-Alins, Maria J. Calzada

Publikováno v: IBJ Plus.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::96e67f7c22ed72ef2de6a76848353da4
https://doi.org/10.24217/2531-0151.21v1s4.00025

Deregulated cellular circuits driving immunoglobulins and complement consumption associate with the severity of COVID‐19 patients

Autor: Hugh T. Reyburn, Luciana del Campo Guerola, Santiago Sánchez-Alonso, Hortensia de la Fuente, Arantzazu Alfranca, Ligia Gabrie, Maria J. Calzada, José Miguel Rodríguez-Frade, Ana Marcos-Jimenez, Pedro Martínez-Fleta, Mar Valés-Gómez, Miguel Sampedro-Núñez, Enrique Martin-Gayo, Cecilia Muñoz-Calleja, Ildefonso Sánchez-Cerrillo, Tamara Mateu-Albero, Ana Alcaraz-Serna, José M. Casasnovas, Francisco Sánchez-Madrid, Margarita López-Trascasa, Celia López-Sanz, Santos Castañeda, Laura Esparcia, Isidoro González-Álvaro

Publikováno v: European Journal of Immunology
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
Digital.CSIC. Repositorio Institucional del CSIC
Biblos-e Archivo: Repositorio Institucional de la UAM
Universidad Autónoma de Madrid

SARS‐CoV‐2 infection causes an abrupt response by the host immune system, which is largely responsible for the outcome of COVID‐19. We investigated whether the specific immune responses in the peripheral blood of 276 patients associated to seve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b932d9d38f8eb47b4f8d093c893e460c
http://europepmc.org/articles/PMC7753288

Deregulated cellular circuits driving immunoglobulins and complement consumption associate with the severity of COVID-19

Autor: Laura Esparcia, Miguel Sampedro-Núñez, Enrique Martin-Gayo, Arantzazu Alfranca, Ildefonso Sánchez-Cerrillo, Luciana del Campo Guerola, Santos Castañeda, Ana Marcos-Jimenez, Ligia Gabrie, Pedro Martínez-Fleta, Ana Alcaraz-Serna, Santiago Sánchez-Alonso, Tamara Mateu-Albero, Celia López-Sanz, Margarita López-Trascasa, Francisco Sánchez-Madrid, Hortensia de la Fuente, Isidoro González-Álvaro, Maria J. Calzada, Cecilia Muñoz-Calleja

BackgroundSARS-CoV-2 infection causes an abrupt response by the host immune system, which is largely responsible for the pathogenesis and outcome of COVID-19. We aimed to investigate which specific responses from either cellular or humoral immunity a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9e0da234293474cac4dde69072b50ea7
https://doi.org/10.1101/2020.06.15.20131706