Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Maria J Perugorria"'
Autor:
Ane Olazagoitia‐Garmendia, Henar Rojas‐Márquez, Maialen Sebastian‐delaCruz, Aloña Agirre‐Lizaso, Anne Ochoa, Luis Manuel Mendoza‐Gomez, Maria J Perugorria, Luis Bujanda, Alain Huerta Madrigal, Izortze Santin, Ainara Castellanos‐Rubio
Publikováno v:
Advanced Science, Vol 11, Iss 13, Pp n/a-n/a (2024)
Abstract Cytokine mediated sustained inflammation increases the risk to develop different complex chronic inflammatory diseases, but the implicated mechanisms remain unclear. Increasing evidence shows that long noncoding RNAs (lncRNAs) play key roles
Externí odkaz:
https://doaj.org/article/2f41a2bb7e6d45ddbe55bfb28e891916
Autor:
Pablo Fernández-Tussy, Rubén Rodríguez-Agudo, David Fernández-Ramos, Lucía Barbier-Torres, Imanol Zubiete-Franco, Sergio López de Davalillo, Elisa Herraez, Naroa Goikoetxea-Usandizaga, Sofia Lachiondo-Ortega, Jorge Simón, Fernando Lopitz-Otsoa, Virginia Gutiérrez-de Juan, Misti V. McCain, Maria J. Perugorria, Jon Mabe, Nicolás Navasa, Cecilia M. P. Rodrigues, Isabel Fabregat, Loreto Boix, Victor Sapena, Juan Anguita, Shelly C. Lu, José M. Mato, Jesus M. Banales, Erica Villa, Helen L. Reeves, Jordi Bruix, Maria Reig, Jose J. G. Marin, Teresa C. Delgado, María L. Martínez-Chantar
Publikováno v:
Cell Death and Disease, Vol 12, Iss 6, Pp 1-16 (2021)
Abstract Dysregulation of miRNAs is a hallmark of cancer, modulating oncogenes, tumor suppressors, and drug responsiveness. The multi-kinase inhibitor sorafenib is one of the first-line drugs for advanced hepatocellular carcinoma (HCC), although the
Externí odkaz:
https://doaj.org/article/fb7ef154614446039d3b36ccb14472c8
Autor:
Ibone Labiano, Aloña Agirre-Lizaso, Paula Olaizola, Anne Echebarria, Maider Huici-Izagirre, Irene Olaizola, Aitor Esparza-Baquer, Omar Sharif, Elizabeth Hijona, Piotr Milkiewicz, Malgorzata Milkiewicz, Francisco González-Romero, Patricia Aspichueta, Maria J. Monte, Jose J.G. Marin, Mihael Vucur, Tom Luedde, Marco Marzioni, Derek A. Mann, Luis Bujanda, Pedro M. Rodrigues, Jesus M. Banales, Maria J. Perugorria
Publikováno v:
Journal of Hepatology
Backgroundand aims: inflammation, particularly that mediated by bacterial components translocating from the gut to the liver and binding to toll-like receptors (TLRs), is central to cholestatic liver injury. The triggering receptor expressed on myelo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb2c60dc6efe95c81adaffe32d01e643
https://doi.org/10.1016/j.jhep.2022.05.044
https://doi.org/10.1016/j.jhep.2022.05.044
Autor:
Paula Olaizola, Pui Yuen Lee-Law, Maite G. Fernandez-Barrena, Laura Alvarez, Massimiliano Cadamuro, Mikel Azkargorta, Colm J. O’Rourke, Francisco J. Caballero-Camino, Irene Olaizola, Rocio I.R. Macias, Jose J.G. Marin, Marina Serrano-Maciá, Maria L. Martinez-Chantar, Matias A. Avila, Patricia Aspichueta, Diego F. Calvisi, Matthias Evert, Luca Fabris, Rui E. Castro, Felix Elortza, Jesper B. Andersen, Luis Bujanda, Pedro M. Rodrigues, Maria J. Perugorria, Jesus M. Banales
Publikováno v:
Olaizola, P, Lee-Law, P Y, Fernandez-Barrena, M G, Alvarez, L, Cadamuro, M, Azkargorta, M, O'Rourke, C J, Caballero-Camino, F J, Olaizola, I, Macias, R I R, Marin, J J G, Serrano-Maciá, M, Martinez-Chantar, M L, Avila, M A, Aspichueta, P, Calvisi, D F, Evert, M, Fabris, L, Castro, R E, Elortza, F, Andersen, J B, Bujanda, L, Rodrigues, P M, Perugorria, M J & Banales, J M 2022, ' Targeting NAE1-mediated protein hyper-NEDDylation halts cholangiocarcinogenesis and impacts on tumor-stroma crosstalk in experimental models ', Journal of Hepatology, vol. 77, no. 1, pp. 177-190 . https://doi.org/10.1016/j.jhep.2022.02.007
Addi. Archivo Digital para la Docencia y la Investigación
instname
Addi. Archivo Digital para la Docencia y la Investigación
instname
[EN] BACKGROUND & AIMS: Cholangiocarcinoma (CCA) comprises a heterogeneous group of malignant tumors associated with dismal prognosis. Alterations in post-translational modifications (PTMs), including NEDDylation, result in abnormal protein dynamics,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afc951961d3c4bc25aa43db66243e451
https://doi.org/10.1016/j.jhep.2022.02.007
https://doi.org/10.1016/j.jhep.2022.02.007
Autor:
Francisco J. Caballero-Camino, Pedro M. Rodrigues, Fredrik Wångsell, Aloña Agirre-Lizaso, Paula Olaizola, Laura Izquierdo-Sanchez, Maria J. Perugorria, Luis Bujanda, Bo Angelin, Sara Straniero, Anna Wallebäck, Ingemar Starke, Per-Göran Gillberg, Ellen Strängberg, Britta Bonn, Jan P. Mattsson, Martin R. Madsen, Henrik H. Hansen, Erik Lindström, Peter Åkerblad, Jesus M. Banales
Publikováno v:
Hepatology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c65ae11a3e0cdc9d6bbaa3a8a7fd946a
https://doi.org/10.1097/hep.0000000000000376
https://doi.org/10.1097/hep.0000000000000376
Autor:
Patricia Aspichueta, Ana M. Zubiaga, Luis Castaño, Maria L. Martínez-Chantar, Jesus M. Banales, Javier Crespo, Paula Iruzubieta, Idoia Martinez de la Piscina, Sonia Gaztambide, Lorena Mosteiro, Gaizka Errazti, Maria J. Perugorria, Igotz Delgado, Sanjay Bhanot, Richard Lee, Naroa Goikoetxea-Usandizaga, Teresa C. Delgado, Virginia Gutierrez De Juan, Irantzu Bernales, Ainhoa Iglesias-Ara, Xabier Buqué, Larraitz Fernández-Ares, Juan L. García-Rodríguez, Maitane Núñez-García, Diego Sáenz de Urturi, Beatriz Gómez-Santos, Marta Palomo-Irigoyen, Marta Varela-Rey, Miguel Tamayo-Caro, Ashwin Woodhoo, Jesper B. Andersen, Colm J. O'Rourke, Igor Aurrekoetxea, Daniela Mestre, Francisco González-Romero
Supplementary Table 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ddf213946fc87fd4f283ab64b4cde07
https://doi.org/10.1158/0008-5472.22430244
https://doi.org/10.1158/0008-5472.22430244
Autor:
Patricia Aspichueta, Ana M. Zubiaga, Luis Castaño, Maria L. Martínez-Chantar, Jesus M. Banales, Javier Crespo, Paula Iruzubieta, Idoia Martinez de la Piscina, Sonia Gaztambide, Lorena Mosteiro, Gaizka Errazti, Maria J. Perugorria, Igotz Delgado, Sanjay Bhanot, Richard Lee, Naroa Goikoetxea-Usandizaga, Teresa C. Delgado, Virginia Gutierrez De Juan, Irantzu Bernales, Ainhoa Iglesias-Ara, Xabier Buqué, Larraitz Fernández-Ares, Juan L. García-Rodríguez, Maitane Núñez-García, Diego Sáenz de Urturi, Beatriz Gómez-Santos, Marta Palomo-Irigoyen, Marta Varela-Rey, Miguel Tamayo-Caro, Ashwin Woodhoo, Jesper B. Andersen, Colm J. O'Rourke, Igor Aurrekoetxea, Daniela Mestre, Francisco González-Romero
Lipid metabolism rearrangements in nonalcoholic fatty liver disease (NAFLD) contribute to disease progression. NAFLD has emerged as a major risk for hepatocellular carcinoma (HCC), where metabolic reprogramming is a hallmark. Identification of metabo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a5c6a7e5944231bd4c670412d55b9a1
https://doi.org/10.1158/0008-5472.c.6513576.v1
https://doi.org/10.1158/0008-5472.c.6513576.v1
Autor:
Patricia Aspichueta, Ana M. Zubiaga, Luis Castaño, Maria L. Martínez-Chantar, Jesus M. Banales, Javier Crespo, Paula Iruzubieta, Idoia Martinez de la Piscina, Sonia Gaztambide, Lorena Mosteiro, Gaizka Errazti, Maria J. Perugorria, Igotz Delgado, Sanjay Bhanot, Richard Lee, Naroa Goikoetxea-Usandizaga, Teresa C. Delgado, Virginia Gutierrez De Juan, Irantzu Bernales, Ainhoa Iglesias-Ara, Xabier Buqué, Larraitz Fernández-Ares, Juan L. García-Rodríguez, Maitane Núñez-García, Diego Sáenz de Urturi, Beatriz Gómez-Santos, Marta Palomo-Irigoyen, Marta Varela-Rey, Miguel Tamayo-Caro, Ashwin Woodhoo, Jesper B. Andersen, Colm J. O'Rourke, Igor Aurrekoetxea, Daniela Mestre, Francisco González-Romero
1-Supplementary methods 2-Supplementary Figure legends 3-Supplementary references
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c113bd0a2cdcb35d220f3dc823b4840
https://doi.org/10.1158/0008-5472.22430247.v1
https://doi.org/10.1158/0008-5472.22430247.v1
Autor:
Patricia Aspichueta, Ana M. Zubiaga, Luis Castaño, Maria L. Martínez-Chantar, Jesus M. Banales, Javier Crespo, Paula Iruzubieta, Idoia Martinez de la Piscina, Sonia Gaztambide, Lorena Mosteiro, Gaizka Errazti, Maria J. Perugorria, Igotz Delgado, Sanjay Bhanot, Richard Lee, Naroa Goikoetxea-Usandizaga, Teresa C. Delgado, Virginia Gutierrez De Juan, Irantzu Bernales, Ainhoa Iglesias-Ara, Xabier Buqué, Larraitz Fernández-Ares, Juan L. García-Rodríguez, Maitane Núñez-García, Diego Sáenz de Urturi, Beatriz Gómez-Santos, Marta Palomo-Irigoyen, Marta Varela-Rey, Miguel Tamayo-Caro, Ashwin Woodhoo, Jesper B. Andersen, Colm J. O'Rourke, Igor Aurrekoetxea, Daniela Mestre, Francisco González-Romero
Supplementary table 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12aecb548819ccf19cdae6b1b63087f5
https://doi.org/10.1158/0008-5472.22430241.v1
https://doi.org/10.1158/0008-5472.22430241.v1
Autor:
Patricia Aspichueta, Ana M. Zubiaga, Luis Castaño, Maria L. Martínez-Chantar, Jesus M. Banales, Javier Crespo, Paula Iruzubieta, Idoia Martinez de la Piscina, Sonia Gaztambide, Lorena Mosteiro, Gaizka Errazti, Maria J. Perugorria, Igotz Delgado, Sanjay Bhanot, Richard Lee, Naroa Goikoetxea-Usandizaga, Teresa C. Delgado, Virginia Gutierrez De Juan, Irantzu Bernales, Ainhoa Iglesias-Ara, Xabier Buqué, Larraitz Fernández-Ares, Juan L. García-Rodríguez, Maitane Núñez-García, Diego Sáenz de Urturi, Beatriz Gómez-Santos, Marta Palomo-Irigoyen, Marta Varela-Rey, Miguel Tamayo-Caro, Ashwin Woodhoo, Jesper B. Andersen, Colm J. O'Rourke, Igor Aurrekoetxea, Daniela Mestre, Francisco González-Romero
Supplementary table 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::967080dbc227f23c3f05d5e0090bb459
https://doi.org/10.1158/0008-5472.22430238.v1
https://doi.org/10.1158/0008-5472.22430238.v1