Data from A TaqMan Low-Density Array to Predict Outcome in Advanced Hodgkin's Lymphoma Using Paraffin-Embedded Samples

Autor: Juan F. García, Miguel A. Piris, Manolo M. Morente, José F. Tomas, Pedro Sánchez-Godoy, Angel Castaño, Eulogio Conde, Francisco Mazorra, Miguel Mendez, Maria J. Mestre, Cesar Morante, Manuel F. Fresno, Carmen Bellas, Concepción Poderos, Joaquín González-Carrero, Rafael Martinez, Carmen Martin, Carlos Montalbán, Abel Sánchez-Aguilera, Beatriz Sánchez-Espiridión

Purpose: Despite major advances in the treatment of classic Hodgkin's lymphoma (cHL), ∼30% of patients in advanced stages may eventually die as result of the disease, and current methods to predict prognosis are rather unreliable. Thus, the applica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e7ed9fe8b284537352f95352dd1eb6a
https://doi.org/10.1158/1078-0432.c.6517338

Analysis of the mutational landscape of classic Hodgkin lymphoma identifies disease heterogeneity and potential therapeutic targets

Autor: Juan F. García, Beatriz Sanchez-Espiridion, Fernando Burgos, Mónica Estévez, Elena Mata, Javier Menárguez, Ana M. Martín-Moreno, Carlos Montalbán, Miguel A. Piris, Mariano Provencio, Ignacio Varela, Margarita Sánchez-Beato, Eva C. Diaz, Maria J Mestre, Antonio Díaz-López, Carlos Santonja

Publikováno v: Biblos-e Archivo. Repositorio Institucional de la UAM
instname
Oncotarget, 2017, Vol. 8, (No. 67), pp: 111386-111395
Digital.CSIC. Repositorio Institucional del CSIC
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)
Oncotarget
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid

Mata et al.
Defining the mutational landscape of classic Hodgkin lymphoma is still a major research goal. New targeted next-generation sequencing (NGS) techniques may identify pathogenic mechanisms and new therapeutic opportunities related to th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eed9305906adc0072d6d00448fbf708f
https://hdl.handle.net/10486/681138

A TaqMan Low-Density Array to Predict Outcome in Advanced Hodgkin's Lymphoma Using Paraffin-Embedded Samples

Autor: Miguel A. Piris, Cesar Morante, Joaquín González-Carrero, Manolo M. Morente, Maria J Mestre, Carlos Montalbán, Angel Castaño, Beatriz Sanchez-Espiridion, Carmen Martin, Miguel Méndez, Juan F. García, Carmen Bellas, Eulogio Conde, Pedro Sánchez-Godoy, Concepción Poderos, Rafael Martínez, Manuel F. Fresno, Francisco Mazorra, Jose Francisco Tomas, Abel Sánchez-Aguilera

Publikováno v: Clinical Cancer Research. 15:1367-1375

Purpose: Despite major advances in the treatment of classic Hodgkin's lymphoma (cHL), ∼30% of patients in advanced stages may eventually die as result of the disease, and current methods to predict prognosis are rather unreliable. Thus, the applica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75d2ecd096301e9dc4e0749e399e9f86
https://doi.org/10.1158/1078-0432.ccr-08-1119

Hodgkin and Reed-Sternberg cells harbor alterations in the major tumor suppressor pathways and cell-cycle checkpoints: analyses using tissue microarrays

Autor: Tomás Álvaro, Máximo Fraga, Javier Menárguez, Angel Castaño, Carmen San Martín, Francisco Mazorra, Carlos Montalbán, Ana I. Sáez, Ana Díez, Miguel A. Martinez, Manuel M. Morente, Juan F. García, Carmen Bellas, Miguel A. Piris, Manuela Mollejo, Maria J Mestre, Francisca I. Camacho, Teresa Flores, Lydia Sánchez

Publikováno v: Blood. 101:681-689

Tumoral cells in Hodgkin lymphoma (HL) display an increased growth fraction and diminished apoptosis, implying a profound disturbance of the cell cycle and apoptosis regulation. However, limitations of molecular techniques have prevented the analysis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8de1c973d8015f0423b7a6a4df4a1f12
https://doi.org/10.1182/blood-2002-04-1128

Rhabdomyosarcoma presenting with diffuse bone marrow involvement, hypercalcemia and renal failure

Autor: Miguel Ángel Martínez, Maria Dolores Valdes, Francisco Javier De La Serna, José M. Morales, Javier Hornedo, Maria J Mestre

Publikováno v: Medical and pediatric oncology. 16(2)

Rhabdomyosarcoma and other small round-cell neoplasms of infancy and childhood frequently involve the bone marrow. An unusual clinical presentation of diffuse bone marrow involvement as the sole manifestation of the disease represents a difficult dia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0a9f433dcc46bc4918c7d109cc7b7ac
https://pubmed.ncbi.nlm.nih.gov/3352535