Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Maria J Barrero"'
Autor:
Julio Castaño, Cristina Morera, Borja Sesé, Stephanie Boue, Carles Bonet-Costa, Merce Martí, Alicia Roque, Albert Jordan, Maria J Barrero
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149502 (2016)
The successful use of specialized cells in regenerative medicine requires an optimization in the differentiation protocols that are currently used. Understanding the molecular events that take place during the differentiation of human pluripotent cel
Externí odkaz:
https://doaj.org/article/e4bdd72e698c4cf49cc278d73bbe9fa6
Autor:
Raquel Coronel, Enrique García-Moreno, Emilio Siendones, Maria J. Barrero, Beatriz Martínez-Delgado, Carlos Santos-Ocaña, Isabel Liste, M. V. Cascajo-Almenara
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
Mitochondrial diseases are a group of severe pathologies that cause complex neurodegenerative disorders for which, in most cases, no therapy or treatment is available. These organelles are critical regulators of both neurogenesis and homeostasis of t
Externí odkaz:
https://doaj.org/article/f1f06f578b714f0ba201ad5a2ef778a9
Publikováno v:
Epigenomes, Vol 6, Iss 3, p 21 (2022)
Rare diseases affect more than 300 million people worldwide. Diagnosing rare diseases is a major challenge as they have different causes and etiologies. Careful assessment of clinical symptoms often leads to the testing of the most common genetic alt
Externí odkaz:
https://doaj.org/article/b2b31497be3e4b459901aa220cc8e505
Autor:
Maria J. Barrero, Ana González-Corpas, Jacinto Sarmentero, Sergio Ruiz-Llorente, Veronica Garcia-Carpizo
Changes in gene expression caused by the treatments. (a) Log2 of fold change to DMSO of all genes after treatment of the indicated cell lines with 150nM JQ1 or 2μM CBP30 for 48 hours (b) Overlap of downregulated and upregulated genes (FDR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f1260bb1abe8d1d70d6833bd03323fd
https://doi.org/10.1158/1541-7786.22515888
https://doi.org/10.1158/1541-7786.22515888
Autor:
Maria J. Barrero, Ana González-Corpas, Jacinto Sarmentero, Sergio Ruiz-Llorente, Veronica Garcia-Carpizo
Oligonucleotides used in this study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e4b253855c1f2707bc954e787256a68
https://doi.org/10.1158/1541-7786.22515870
https://doi.org/10.1158/1541-7786.22515870
Autor:
Maria J. Barrero, Ana González-Corpas, Jacinto Sarmentero, Sergio Ruiz-Llorente, Veronica Garcia-Carpizo
Inhibitors that prevent the binding of bromodomains to acetylated histones hold therapeutic potential. However, the effects of targeting most of the 60 different bromodomains found in the human proteome remain unexplored. Here, we investigate the mol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5fc2e1253a553a0211f866e1a754da3
https://doi.org/10.1158/1541-7786.c.6541209
https://doi.org/10.1158/1541-7786.c.6541209
Autor:
Maria J. Barrero
Publikováno v:
Epigenomes, Vol 4, Iss 3, p 22 (2020)
The contribution of the non-coding genome to disease and its therapeutic potential have been largely unexplored. Recently, several epigenetic drugs developed for cancer treatment have been described to mediate therapeutic effects through the reactiva
Externí odkaz:
https://doaj.org/article/03ded787dbe14a00af8a1296b6e7237e
Autor:
Beatriz Baladron, Lidia M. Mielu, Estrella López-Martín, Maria J. Barrero, Lidia Lopez, Jose I. Alvarado, Sara Monzón, Sarai Varona, Isabel Cuesta, Rosario Cazorla, Julián Lara, Gemma Iglesias, Enriqueta Román, Purificación Ros, Gema Gomez-Mariano, Isabel Cubillo, Esther Hernandez-San Miguel, Daniel Rivera, Javier Alonso, Eva Bermejo-Sánchez, Manuel Posada, Beatriz Martínez-Delgado
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 16; Pages: 9480
Repisalud
Instituto de Salud Carlos III (ISCIII)
Repisalud
Instituto de Salud Carlos III (ISCIII)
Pathogenic hemizygous or heterozygous mutations in the IQSEC2 gene cause X-linked intellectual developmental disorder-1 (XLID1), characterized by a variable phenotype including developmental delay, intellectual disability, epilepsy, hypotonia, autism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b9b6795c1aa51afc2e89ead485ced9e
Autor:
Maria J. Barrero, Stella Pappa, Izaskun Mallona, Miguel A. Peinado, Joaquin Custodio, Berta Martín, Anna Díez-Villanueva, Mireia Jordà
Publikováno v:
Epigenetics
Alu repeats constitute a major fraction of human genome and for a small subset of them a role in gene regulation has been described. The number of studies focused on the functional characterization of particular Alu elements is very limited. Most Alu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89d10d4ae1a9569a0007ba534c72b504
https://doi.org/10.1080/15592294.2020.1722398
https://doi.org/10.1080/15592294.2020.1722398
Publikováno v:
Adv Nutr
Alterations in the epigenome are well known to affect cancer development and progression. Epigenetics is highly influenced by the environment, including diet, which is a source of metabolic substrates that influence the synthesis of cofactors or subs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8bcc004f84260d4a6ba700376bc7702
https://pubmed.ncbi.nlm.nih.gov/35421212
https://pubmed.ncbi.nlm.nih.gov/35421212