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of 15
pro vyhledávání: '"Maria Izco"'
Autor:
Elba Beraza, Maria Serrano-Civantos, Maria Izco, Lydia Alvarez-Erviti, Elena Gonzalez-Peñas, Ariane Vettorazzi
Publikováno v:
Toxins, Vol 16, Iss 5, p 213 (2024)
Ochratoxin A (OTA) is a mycotoxin commonly found in various food products, which poses potential health risks to humans and animals. Recently, more attention has been directed towards its potential neurodegenerative effects. However, there are curren
Externí odkaz:
https://doaj.org/article/d02600ad09494f2994785ae709ce0fc9
Autor:
Maria Izco, Martin Schleef, Marco Schmeer, Estefania Carlos, Guglielmo Verona, Lydia Alvarez-Erviti
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1230 (2023)
The development of effective disease-modifying therapies to halt Parkinson’s disease (PD) progression is required. In a subtype of PD patients, alpha-synuclein pathology may start in the enteric nervous system (ENS) or autonomic peripheral nervous
Externí odkaz:
https://doaj.org/article/52deb2fc5a634c29a3baa0cad096c317
Publikováno v:
Neurobiology of Disease, Vol 166, Iss , Pp 105651- (2022)
Although the factors contributing to the pathogenesis of neurodegenerative diseases remain elusive, endolysosomal pathway is emerging as a key player in the pathogenesis of neurodegenerative diseases. The link between endolysosomal dysfunction and ne
Externí odkaz:
https://doaj.org/article/373cd47d289840bbb7387d765229031e
Akademický článek
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Autor:
Ariadna Fernández-Calvet, Leticia Matilla-Cuenca, María Izco, Susanna Navarro, Miriam Serrano, Salvador Ventura, Javier Blesa, Maite Herráiz, Gorka Alkorta-Aranburu, Sergio Galera, Igor Ruiz de los Mozos, María Luisa Mansego, Alejandro Toledo-Arana, Lydia Alvarez-Erviti, Jaione Valle
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Age-related neurodegenerative diseases involving amyloid aggregation remain one of the biggest challenges of modern medicine. Alterations in the gastrointestinal microbiome play an active role in the aetiology of neurological disorders. Here
Externí odkaz:
https://doaj.org/article/40b541987ebf412386b91ac11bd1521e
Autor:
Elisa Torres, Andrea Mayado, Esther O'Shea, Maria Izco, M.I. Colado, José Antonio López-Moreno, A Lopez-Jimenez, Ines Peraile
Publikováno v:
British Journal of Pharmacology. 159:201-211
¥2 for 3 days) followed by MDMA (20 mg·kg -1 , ¥2, 3 h apart). Locomotor activity, extracellular dopamine levels and dopaminergic neurotoxicity were determined. Furthermore, following the course of cocaine, DAT density in striatal plasma membrane
Autor:
Ivanny Marchant, María Isabel Colado, María Dolores Gutiérrez-López, Esther O'Shea, Maria Izco
Publikováno v:
Psychopharmacology. 207:671-679
Mice with reduced dopamine activity following neurotoxic doses of 3,4-methylenedioxymethamphetamine (MDMA, ‘ecstasy’) consume more ethanol (EtOH) and show greater preference for EtOH. In keeping with human studies and other animal models where al
Publikováno v:
Neurotoxicity Research. 18:187-199
3,4-Methylenedioxymethamphetamine (MDMA, 'ecstasy') is a selective 5-HT neurotoxin in rat brain which has been shown to produce acute neuroinflammation characterized by activation of microglia and release of interleukin-1beta (IL-1beta). We aimed to
Autor:
M. Isabel Colado, Maria Izco, Esther O'Shea, Isabel Escobedo, Ines Peraile, Emilio Ambrosio, Mercedes Delgado, Ivanny Marchant, Alejandro Higuera-Matas, Oscar Olias
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 322:1003-1012
MDMA (3,4-methylenedioxymethamphetamine, "ecstasy") administration to mice produces relatively selective long-term neurotoxic damage to dopaminergic pathways. There is strong evidence indicating that the dopamine system plays a key role in the reward
Publikováno v:
Psychopharmacology. 189(4)
Ecstasy abuse commonly occurs in hot, overcrowded environments in combination with alcohol. Around 90% of ecstasy users take ethanol; over 70% of these users also often drink alcohol at hazardous levels.We wished to examine whether binge ethanol admi