Multifaceted WNT Signaling at the Crossroads Between Epithelial-Mesenchymal Transition and Autophagy in Glioblastoma

Autor: Bárbara Paranhos Coelho, Camila Felix de Lima Fernandes, Jacqueline Marcia Boccacino, Maria Clara da Silva Souza, Maria Isabel Melo-Escobar, Rodrigo Nunes Alves, Mariana Brandão Prado, Rebeca Piatniczka Iglesia, Giovanni Cangiano, Giulia La Rocca Mazzaro, Marilene Hohmuth Lopes

Publikováno v: Frontiers in Oncology, Vol 10 (2020)

Tumor cells can employ epithelial-mesenchymal transition (EMT) or autophagy in reaction to microenvironmental stress. Importantly, EMT and autophagy negatively regulate each other, are able to interconvert, and both have been shown to contribute to d

Externí odkaz: https://doaj.org/article/f2985f9727aa4b3e8efc46a8e8678884

Extracellular vesicles throughout development: A potential roadmap for emerging glioblastoma therapies

Autor: Camila Felix de Lima Fernandes, Bárbara Paranhos Coelho, Maria Clara da Silva Souza, Jacqueline Marcia Boccacino, Samuel Ribeiro Soares, João Pedro Alves de Araújo, Maria Isabel Melo-Escobar, Marilene Hohmuth Lopes

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Extracellular vesicles (EVs) are membrane-delimited vesicular bodies carrying different molecules, classified according to their size, density, cargo, and origin. Research on this topic has been actively growing through the years, as EVs are associat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fb2a49622a0bfb078b3b4341f4a8f41
https://pubmed.ncbi.nlm.nih.gov/35697594

A New Take on Prion Protein Dynamics in Cellular Trafficking

Autor: Marilene H. Lopes, Rebeca Piatniczka Iglesia, Bárbara Paranhos Coelho, Mariana Brandão Prado, Camila Felix de Lima Fernandes, Ailine Cibele Fortes, Jacqueline Marcia Boccacino, Rodrigo Nunes Alves, Maria Isabel Melo Escobar

Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 7763, p 7763 (2020)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
International Journal of Molecular Sciences

The mobility of cellular prion protein (PrPC) in specific cell membrane domains and among distinct cell compartments dictates its molecular interactions and directs its cell function. PrPC works in concert with several partners to organize signaling

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d20713b3758452761641398074011d8b
https://www.mdpi.com/1422-0067/21/20/7763

Prion protein at the leading edge: its role in cell motility

Autor: Maria Isabel Melo Escobar, Bárbara Paranhos Coelho, Marilene H. Lopes, Rodrigo Nunes Alves, Rebeca Piatniczka Iglesia, Mariana Brandão Prado, Jacqueline Marcia Boccacino, Camila Felix de Lima Fernandes

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 6677, p 6677 (2020)

Cell motility is a central process involved in fundamental biological phenomena during embryonic development, wound healing, immune surveillance, and cancer spreading. Cell movement is complex and dynamic and requires the coordinated activity of cyto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c1fd2a9cc26cdb2778c34114872e598

Chaperones and Beyond as Key Players in Pluripotency Maintenance

Autor: Marilene H. Lopes, Rebeca Piatniczka Iglesia, Camila Felix de Lima Fernandes, Mariana Brandão Prado, Maria Isabel Melo-Escobar

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 7 (2019)
Frontiers in Cell and Developmental Biology
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Pluripotency is orchestrated by distinct players and chaperones and their partners have emerged as pivotal molecules in proteostasis control to maintain stemness. The proteostasis network consists of diverse interconnected pathways that function dyna

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cbd6d73e914f97a9417d48482adc82a
https://www.frontiersin.org/article/10.3389/fcell.2019.00150/full