Susceptibility to Leprosy is Associated with M-ficolin Polymorphisms

Autor: Ewalda von Rosen Seeling Stahlke, Jürgen F. J. Kun, Maria Iolanda N Sanchez, Steffen Thiel, Iara J.T. Messias-Reason, Jens C. Jensenius, Angelica Beate Winter Boldt, Marcelo Távora Mira, Flávia Costa Prevedello, Rudi Steffensen

Publikováno v: Boldt, A B W, Sanchez, M I N, Stahlke, E R S, Steffensen, R, Thiel, S, Jensenius, J C, Prevedello, F C, Mira, M T, Kun, J F J & Messias-Reason, I J T 2013, ' Susceptibility to leprosy is associated with M-ficolin polymorphisms ', Journal of Clinical Immunology, vol. 33, no. 1, pp. 210-9 . https://doi.org/10.1007/s10875-012-9770-4
Boldt, A B W, Sanchez, M I N, Stahlke, E R S, Steffensen, R, Thiel, S, Jensenius, J C, Prevedello, F C, Mira, M T, Kun, J F J & Messias-Reason, I J T 2013, ' Susceptibility to Leprosy is Associated with M-ficolin Polymorphisms ', Journal of Clinical Immunology, vol. 33, no. 1, pp. 210-9 . https://doi.org/10.1007/s10875-012-9770-4

PURPOSE: Mycobacterium leprae exploits complement activation and opsonophagocytosis to infect phagocytes. M-ficolin is encoded by the FCN1 gene and initiates the lectin pathway on monocyte surfaces. We investigated FCN1 promoter polymorphisms that co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22a5949b3deed1936c788a7be83208b2
https://doi.org/10.1007/s10875-012-9770-4