Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Maria Inasu"'
Publikováno v:
Breast, Vol 61, Iss , Pp 123-128 (2022)
Background: Accumulating evidence suggests that statins have a beneficial effect on breast cancer prognosis. Previous studies have reported a positive association between statin use and breast cancer survival; however, the relationship between statin
Externí odkaz:
https://doaj.org/article/467dc94c604b495ab4d76c932a1cf9c9
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-11 (2021)
Abstract 27-hydroxycholesterol (27HC), synthesized from cholesterol by the enzyme CYP27A1, differentially impacts estrogen receptor positive (ER+) breast cancer (BC) cell growth depending on estrogen levels. This study examined the association betwee
Externí odkaz:
https://doaj.org/article/42ce64d0f0ad4806b4fab2233af6540e
Autor:
Siker Kimbung, Maria Inasu, Tor Stålhammar, Björn Nodin, Karin Elebro, Helga Tryggvadottir, Maria Ygland Rödström, Karin Jirström, Karolin Isaksson, Helena Jernström, Signe Borgquist
Publikováno v:
Breast Cancer Research, Vol 22, Iss 1, Pp 1-13 (2020)
Abstract Background 27-Hydroxycholesterol (27HC) stimulates estrogen receptor-positive (ER+) breast cancer (BC) progression. Inhibiting the sterol 27-hydroxylase (CYP27A1) abrogates these growth-promoting effects of 27HC in mice. However, the signifi
Externí odkaz:
https://doaj.org/article/dc9b2df2276b447bbb83d11c19cb5da6
Autor:
Siker Kimbung, Pär-Ola Bendahl, Signe Borgquist, Maria Inasu, Mårten Fernö, Per-Uno Malmström
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-11 (2021)
NPJ Breast Cancer
Inasu, M, Bendahl, P O, Fernö, M, Malmström, P, Borgquist, S & Kimbung, S 2021, ' High CYP27A1 expression is a biomarker of favorable prognosis in premenopausal patients with estrogen receptor positive primary breast cancer ', npj Breast Cancer, vol. 7, no. 1, 127 . https://doi.org/10.1038/s41523-021-00333-6
NPJ Breast Cancer
Inasu, M, Bendahl, P O, Fernö, M, Malmström, P, Borgquist, S & Kimbung, S 2021, ' High CYP27A1 expression is a biomarker of favorable prognosis in premenopausal patients with estrogen receptor positive primary breast cancer ', npj Breast Cancer, vol. 7, no. 1, 127 . https://doi.org/10.1038/s41523-021-00333-6
27-hydroxycholesterol (27HC), synthesized from cholesterol by the enzyme CYP27A1, differentially impacts estrogen receptor positive (ER+) breast cancer (BC) cell growth depending on estrogen levels. This study examined the association between CYP27A1
Autor:
Signe Borgquist, Siker Kimbung, Pär-Ola Bendahl, Mårten Fernö, Maria Inasu, Per-Uno Malmström
Publikováno v:
Cancer Research. 80:P3-08
Background: Experimental evidence suggests that pathogenicity caused by cholesterol in breast cancer is partly elicited by 27-hydroxycholesterol (27HC), a primary cholesterol metabolite produced by the sterol 27-hydroxylase cytochrome p450 27A1 (CYP2
Publikováno v:
The Breast : Official Journal of the European Society of Mastology
Inasu, M, Feldt, M, Jernström, H, Borgquist, S & Harborg, S 2022, ' Statin use and patterns of breast cancer recurrence in the Malmö Diet and Cancer Study ', Breast, vol. 61, pp. 123-128 . https://doi.org/10.1016/j.breast.2022.01.003
Breast, Vol 61, Iss, Pp 123-128 (2022)
Inasu, M, Feldt, M, Jernström, H, Borgquist, S & Harborg, S 2022, ' Statin use and patterns of breast cancer recurrence in the Malmö Diet and Cancer Study ', Breast, vol. 61, pp. 123-128 . https://doi.org/10.1016/j.breast.2022.01.003
Breast, Vol 61, Iss, Pp 123-128 (2022)
Background Accumulating evidence suggests that statins have a beneficial effect on breast cancer prognosis. Previous studies have reported a positive association between statin use and breast cancer survival; however, the relationship between statin
Autor:
Helena Jernström, Carsten Rose, Siker Kimbung, K Elebro, Christian Ingvar, Maria Inasu, Signe Borgquist, Helga Tryggvadottir, Karin Jirström, Björn Nodin, T Stålhammar
Publikováno v:
Cancer Research. 79:P2-08
Background: Pre-clinical and epidemiological data strongly link high cholesterol with breast cancer progression and poor prognosis. It was recently uncovered that the pathogenicity of cholesterol in breast cancer is directly propagated by 27-hydroxyc
Autor:
Helena Jernström, Maria Ygland Rödström, Karin Jirström, Siker Kimbung, Maria Inasu, Tor Stålhammar, Karin Elebro, Signe Borgquist, Karolin Isaksson, Helga Tryggvadottir, Björn Nodin
Publikováno v:
Kimbung, S, Inasu, M, Stålhammar, T, Nodin, B, Elebro, K, Tryggvadottir, H, Ygland Rödström, M, Jirström, K, Isaksson, K, Jernström, H & Borgquist, S 2020, ' CYP27A1 expression is associated with risk of late lethal estrogen receptor-positive breast cancer in postmenopausal patients ', Breast Cancer Research, vol. 22, 123 . https://doi.org/10.1186/s13058-020-01347-x
Breast Cancer Research : BCR
Breast Cancer Research, Vol 22, Iss 1, Pp 1-13 (2020)
Breast Cancer Research : BCR
Breast Cancer Research, Vol 22, Iss 1, Pp 1-13 (2020)
Background 27-Hydroxycholesterol (27HC) stimulates estrogen receptor-positive (ER+) breast cancer (BC) progression. Inhibiting the sterol 27-hydroxylase (CYP27A1) abrogates these growth-promoting effects of 27HC in mice. However, the significance of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f26c05630578c90b2d9d6238ce96387
https://pure.au.dk/portal/da/publications/cyp27a1-expression-is-associated-with-risk-of-late-lethal-estrogen-receptorpositive-breast-cancer-in-postmenopausal-patients(f6fc976a-5b22-45fb-a5b1-391cb734db24).html
https://pure.au.dk/portal/da/publications/cyp27a1-expression-is-associated-with-risk-of-late-lethal-estrogen-receptorpositive-breast-cancer-in-postmenopausal-patients(f6fc976a-5b22-45fb-a5b1-391cb734db24).html
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Apart from the relevant lipid-lowering effects, statins have demonstrated significant, although heterogeneous, anti-tumor activities in preventing breast cancer (BC) progression. To characterize the critical pathways behind the diverse responses to t