Hepatic expression of lipopolysaccharide-binding protein (Lbp) is induced by the gut microbiota through Myd88 and impairs glucose tolerance in mice independent of obesity

Autor: Alba Carreras, Ara Koh, Anna Hallén, Fredrik Bäckhed, Maria Ilaria Faggi, Hao Wu, Robert Caesar, Antonio Molinaro, Marc Schoeler

Publikováno v: Molecular Metabolism
Molecular Metabolism, Vol 37, Iss, Pp 100997-(2020)
Molinaro, A, Koh, A, Wu, H, Schoeler, M, Faggi, M I, Carreras, A, Hallen, A, Backhed, F & Caesar, R 2020, ' Hepatic expression of lipopolysaccharide-binding protein ( Lbp ) is induced by the gut microbiota through Myd88 and impairs glucose tolerance in mice independent of obesity ', Molecular Metabolism, vol. 37, 100997 . https://doi.org/10.1016/j.molmet.2020.100997

Objective Gut-derived inflammatory factors can impair glucose homeostasis, but the underlying mechanisms are not fully understood. In this study, we investigated how hepatic gene expression is regulated by gut colonization status through myeloid diff

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d291130f495007f9efd551b2e85ce6d3
https://pubmed.ncbi.nlm.nih.gov/32305515