Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Maria I. Tarazona Guzman"'
Autor:
Wai Cheung Chan, Xiaoxi Liu, Robert S. Magin, Nicholas M. Girardi, Scott B. Ficarro, Wanyi Hu, Maria I. Tarazona Guzman, Cara A. Starnbach, Alejandra Felix, Guillaume Adelmant, Anthony C. Varca, Bin Hu, Ariana S. Bratt, Ethan DaSilva, Nathan J. Schauer, Isabella Jaen Maisonet, Emma K. Dolen, Anthony X. Ayala, Jarrod A. Marto, Sara J. Buhrlage
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Deubiquitinases (DUBs) are key signaling enzymes, many of which lack selective inhibitors. Chan et al. pair a DUB-focused covalent library to mass spectrometry activity-based protein profiling, leading to selective hits against 23 endogenous DUBs and
Externí odkaz:
https://doaj.org/article/d6b807ef0bbf47468c2c964d3363d37f
Publikováno v:
ACS Chem Biol
Histone methyltransferases (HMTs) are enzymes that catalyze the methylation of lysine or arginine residues of histone proteins, a key post-translational modification (PTM). Aberrant expression or activity of these enzymes can lead to abnormal histone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d47ccac934207f1c8b9d11438307b831
https://europepmc.org/articles/PMC9336197/
https://europepmc.org/articles/PMC9336197/