Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Maria I. Matias"'
Autor:
Maria I. Matias, Carmen S. Yong, Amir Foroushani, Chloe Goldsmith, Cédric Mongellaz, Erdinc Sezgin, Kandice R. Levental, Ali Talebi, Julie Perrault, Anais Rivière, Jonas Dehairs, Océane Delos, Justine Bertand-Michel, Jean-Charles Portais, Madeline Wong, Julien C. Marie, Ameeta Kelekar, Sandrina Kinet, Valérie S. Zimmermann, Ilya Levental, Laurent Yvan-Charvet, Johannes V. Swinnen, Stefan A. Muljo, Hector Hernandez-Vargas, Saverio Tardito, Naomi Taylor, Valérie Dardalhon
Publikováno v:
Cell Reports, Vol 37, Iss 5, Pp 109911- (2021)
Summary: Suppressive regulatory T cell (Treg) differentiation is controlled by diverse immunometabolic signaling pathways and intracellular metabolites. Here we show that cell-permeable α-ketoglutarate (αKG) alters the DNA methylation profile of na
Externí odkaz:
https://doaj.org/article/0c8c5ea249b7400aa1ce379f1a846ac3
Autor:
Chloe Goldsmith, Olivier Fesneau, Valentin Thevin, Maria I. Matias, Julie Perrault, Ali Hani Abid, Naomi Taylor, Valérie Dardalhon, Julien C. Marie, Hector Hernandez-Vargas
Both identity and plasticity of CD4 T helper (Th) cells are regulated in part by epigenetic mechanisms. However, a method that reliably and readily profiles DNA base modifications is still needed to finely study Th cell differentiation. Cytosine meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3bb402ab602b3fc8a593f7ea4251689
https://doi.org/10.1101/2023.02.03.527091
https://doi.org/10.1101/2023.02.03.527091
Autor:
Julie Perrault, Anais Rivière, Chloe Goldsmith, Jonas Dehairs, Cédric Mongellaz, Laurent Yvan-Charvet, Naomi Taylor, Valérie S. Zimmermann, Saverio Tardito, Maria I. Matias, Valerie Dardalhon, Océane Delos, Amir Foroushani, Kandice R. Levental, Stefan A. Muljo, Sandrina Kinet, Ilya Levental, Hector Hernandez-Vargas, Ali Talebi, Jean-Charles Portais, Justine Bertand-Michel, Madeline Wong, Ameeta Kelekar, Julien C. Marie, Johannes V. Swinnen, Carmen S M Yong, Erdinc Sezgin
Publikováno v:
Cell Reports
Cell Reports, 2021, 37 (5), pp.109911. ⟨10.1016/j.celrep.2021.109911⟩
Cell Rep
Cell Reports, Vol 37, Iss 5, Pp 109911-(2021)
Cell Reports, 2021, 37 (5), pp.109911. ⟨10.1016/j.celrep.2021.109911⟩
Cell Rep
Cell Reports, Vol 37, Iss 5, Pp 109911-(2021)
Suppressive regulatory T cell (Treg) differentiation is controlled by diverse immunometabolic signaling pathways and intracellular metabolites. Here we show that cell-permeable α-ketoglutarate (αKG) alters the DNA methylation profile of naive CD4 T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56a0285e83f2c785c903977fe07dec51
https://lirias.kuleuven.be/handle/20.500.12942/691431
https://lirias.kuleuven.be/handle/20.500.12942/691431
Autor:
Madeline Wong, Ilya Levental, Kandice R. Levental, Anais Rivière, Ali Talebi, Erdinc Sezgin, Naomi Taylor, Laurent Yvan-Charvet, Johannes V. Swinnen, Saverio Tardito, Valérie S. Zimmermann, Valerie Dardalhon, Stefan A. Muljo, Jonas Dehair, Amir Foroushani, Carmen S M Yong, Cédric Mongellaz, Sandrina Kinet, Maria I. Matias, Julie Perrault
Publikováno v:
SSRN Electronic Journal.
Suppressive regulatory T cell (Treg) differentiation is controlled by diverse immunometabolic signaling pathways. However, the impact of intracellular metabolites on Treg fate has not been well explored. Here we show that the α-ketoglutarate (αKG)
Autor:
Valerie Dardalhon, Sandrina Kinet, Naomi Taylor, Madeline Wong, J. Dehair, Ilya Levental, Erdinc Sezgin, Maria I. Matias, Cédric Mongellaz, Stefan A. Muljo, Valérie S. Zimmermann, Carmen S M Yong, Triantafyllos Chavakis, Johan Swinnen, Laurent Yvan-Charvet, Kandice R. Levental, Amir Foroushani, Saverio Tardito, Ali Talebi
The differentiation of CD4 T cells to a specific effector fate is metabolically regulated, integrating glycolysis and mitochondrial oxidative phosphorylation (OXPHOS) with transcriptional and epigenetic changes. OXPHOS is tightly coordinated with the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4a581548ca0aa1bcde00c6c0e039b91
https://doi.org/10.1101/2020.08.24.256560
https://doi.org/10.1101/2020.08.24.256560
Publikováno v:
Molecular Cell
Molecular Cell, Elsevier, 2020, 80 (4), pp.555-557. ⟨10.1016/j.molcel.2020.11.005⟩
Molecular Cell, Elsevier, 2020, 80 (4), pp.555-557. ⟨10.1016/j.molcel.2020.11.005⟩
Refers toJun-Kyu Byun, Mihyang Park, Seunghyeong Lee, Jae Won Yun, Jaebon Lee, Jae Sun Kim, Sung Jin Cho, Hui-Jeon Jeon, In-Kyu Lee, Yeon-Kyung Choi, Keun-Gyu ParkInhibition of Glutamine Utilization Synergizes with Immune Checkpoint Inhibitor to Prom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86fd7e505bf6bfaccc379abfd5f31abe
https://hal.archives-ouvertes.fr/hal-03382740/document
https://hal.archives-ouvertes.fr/hal-03382740/document
Autor:
Marco, Craveiro, Gaspard, Cretenet, Cédric, Mongellaz, Maria I, Matias, Olivier, Caron, Maria C Pedroso, de Lima, Valérie S, Zimmermann, Eric, Solary, Valérie, Dardalhon, Vjekoslav, Dulić, Naomi, Taylor
Publikováno v:
Science signaling. 10(501)
The polyphenol resveratrol activates the deacetylase Sirt1, resulting in various antioxidant, chemoprotectant, neuroprotective, cardioprotective, and anti-inflammatory properties. We found that at high concentrations of resveratrol, human CD4
Resveratrol stimulates the metabolic reprogramming of human CD4+T cells to enhance effector function
Autor:
Naomi Taylor, Olivier Caron, Valerie Dardalhon, Marco Craveiro, Vjekoslav Dulic, Maria C. Pedroso de Lima, Cédric Mongellaz, Maria I. Matias, Eric Solary, Valérie S. Zimmermann, Gaspard Cretenet
Publikováno v:
Science Signaling. 10
The polyphenol resveratrol activates the deacetylase Sirt1, resulting in various antioxidant, chemoprotectant, neuroprotective, cardioprotective, and anti-inflammatory properties. We found that at high concentrations of resveratrol, human CD4 + T cel
Autor:
Sandrina Kinet, Leal Oburoglu, Séverine Loisel, Isabelle Clerc, Valerie Dardalhon, Cédric Mongellaz, Naomi Taylor, Maria I. Matias, Gaspard Cretenet, Marco Craveiro
Publikováno v:
Scientific Reports
Scientific Reports, Nature Publishing Group, 2016, 6, pp.24129. ⟨10.1038/srep24129⟩
Scientific Reports, Nature Publishing Group, 2016, 6, pp.24129. 〈10.1038/srep24129〉
Scientific Reports, 2016, 6, pp.24129. ⟨10.1038/srep24129⟩
Scientific Reports, Nature Publishing Group, 2016, 6, pp.24129. ⟨10.1038/srep24129⟩
Scientific Reports, Nature Publishing Group, 2016, 6, pp.24129. 〈10.1038/srep24129〉
Scientific Reports, 2016, 6, pp.24129. ⟨10.1038/srep24129⟩
CD4 and CD8 T lymphocyte activation requires the generation of sufficient energy to support new biosynthetic demands. Following T cell receptor (TCR) engagement, these requirements are met by an increased glycolysis, due, at least in part, to inducti
Autor:
Marco Craveiro, Naomi Taylor, Dorota Klysz, Xuguang Tai, Cédric Mongellaz, Valerie Dardalhon, Carmen S M Yong, Jochen Huehn, Maria I. Matias, Julien C. Marie, Valérie S. Zimmermann, Philippe Robert, Gaspard Cretenet, Natalie Surh, Sandrina Kinet, Stefan Floess, Vanessa Fritz, Leal Oburoglu
Publikováno v:
Science Signaling
Science Signaling, American Association for the Advancement of Science, 2015, 8 (396), pp.ra97. ⟨10.1126/scisignal.aab2610⟩
Science Signaling, American Association for the Advancement of Science, 2015, 8 (396), pp.ra97. ⟨10.1126/scisignal.aab2610⟩
T cell activation requires that the cell meet increased energetic and biosynthetic demands. We showed that exogenous nutrient availability regulated the differentiation of naive CD4(+) T cells into distinct subsets. Activation of naive CD4(+) T cells