Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Maria I. Lind"'
Publikováno v:
JBIC Journal of Biological Inorganic Chemistry. 20:1229-1238
Synthesis of ecdysone, the key hormone that signals the termination of larval growth and the initiation of metamorphosis in insects, is carried out in the prothoracic gland by an array of iron-containing cytochrome P450s, encoded by the halloween gen
Publikováno v:
Insect Science. 19:472-476
Insects protect themselves against microbial infection by an efficient innate immune system that is activated by recognition of invariant microbial surface molecules. In the fruit fly Drosophila me ...
Autor:
Maria I. Lind, Christoph Metzendorf
Publikováno v:
Biochemical and Biophysical Research Communications. 400:442-446
Iron is essential for life and is needed for cell proliferation and cell cycle progression. Iron deprivation results first in cell cycle arrest and then in apoptosis. The Drosophila tumorous larval hemocyte cell line l(2)mbn was used to study the sen
Autor:
Richard Wagner, Maria I. Lind, Michael Meinecke, Martin van der Laan, Dana P. Hutu, Inge Perschil, Bernard Guiard, Nikolaus Pfanner, Peter Rehling, Jan Dudek
Publikováno v:
Nature Cell Biology. 9:1152-1159
The mitochondrial inner membrane is the central energy-converting membrane of eukaryotic cells. The electrochemical proton gradient generated by the respiratory chain drives the ATP synthase. To maintain this proton-motive force, the inner membrane f
Autor:
Kim Kirby, John P. Phillips, Maria I. Lind, Helge Uhrigshardt, Öjar Melefors, Kenneth Söderhäll, Tracey A. Rouault, Fanis Missirlis
Publikováno v:
Journal of Biological Chemistry. 281:18707-18714
In mammalian cells, iron homeostasis is largely regulated by post-transcriptional control of gene expression through the binding of iron-regulatory proteins (IRP1 and IRP2) to iron-responsive elements (IREs) contained in the untranslated regions of t
Publikováno v:
Free radical biologymedicine. 85
Friedreich׳s ataxia is the most important recessive ataxia in the Caucasian population. Loss of frataxin expression affects the production of iron–sulfur clusters and, therefore, mitochondrial energy production. One of the pathological consequence
Autor:
Martin van der Laan, Albert Sickmann, Helmut E. Meyer, Inge Perschil, Chris Meisinger, Maria I. Lind, Agnieszka Chacinska, Bernard Guiard, Nikolaus Pfanner, Peter Rehling
Publikováno v:
Molecular and Cellular Biology. 25:7449-7458
Import of mitochondrial matrix proteins involves the general translocase of the outer membrane and the presequence translocase of the inner membrane. The presequence translocase-associated motor (PAM) drives the completion of preprotein translocation
Autor:
Albert Sickmann, Virginia Bilanchone, M G Cumsky, Kaye N. Truscott, Helmut E. Meyer, Yanfeng Li, Andreas Geissler, Ann E. Frazier, Wolfgang Voos, Chris Meisinger, Maria I. Lind, Peter Rehling, Jan Dudek, Bernard Guiard, Nikolaus Pfanner
Publikováno v:
Nature Structural & Molecular Biology. 11:226-233
Mitochondrial preproteins destined for the matrix are translocated by two channel-forming transport machineries, the translocase of the outer membrane and the presequence translocase of the inner membrane. The presequence translocase-associated prote
Autor:
Yanfeng Li, Chris Meisinger, Bernard Guiard, Maria I. Lind, Nikolaus Pfanner, Peter Rehling, Ann E. Frazier, Helmut E. Meyer, Hanne Müller, Jan Dudek, Andreas Geissler, Wolfgang Voos, Albert Sickmann, Kaye N. Truscott
Publikováno v:
The Journal of Cell Biology
Transport of preproteins into the mitochondrial matrix is mediated by the presequence translocase–associated motor (PAM). Three essential subunits of the motor are known: mitochondrial Hsp70 (mtHsp70); the peripheral membrane protein Tim44; and the
Publikováno v:
Insect Biochemistry and Molecular Biology. 29:1-9
A putative crayfish iron-responsive element (IRE) is present in the 5'-untranslated region of the crayfish ferritin mRNA. The putative crayfish IRE is in a cap-proximal position and shares most of the structural features of the consensus IRE, but the