Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Maria I. L. Soares"'
Autor:
Elizeth Lopes, Gisela Machado-Oliveira, Catarina Guerreiro Simões, Inês S. Ferreira, Cristiano Ramos, José Ramalho, Maria I. L. Soares, Teresa M. V. D. Pinho e Melo, Rosa Puertollano, André R. A. Marques, Otília V. Vieira
Publikováno v:
Cells, Vol 12, Iss 24, p 2826 (2023)
There is growing evidence supporting the role of fibroblasts in all stages of atherosclerosis, from the initial phase to fibrous cap and plaque formation. In the arterial wall, as with macrophages and vascular smooth muscle cells, fibroblasts are exp
Externí odkaz:
https://doaj.org/article/2c8e0449d6354b6885dbf0bf15f81bef
Publikováno v:
Química Nova, Vol 43, Iss 1, Pp 123-126 (2020)
A one-pot diastereoselective synthesis of thiazolidine-ring fused systems derived from enantiomerically pure amino acids, L-cysteine or D-penicillamine, and achiral succindialdehyde is described as an experiment to be carried out by upper-division un
Externí odkaz:
https://doaj.org/article/c746c28401474684a1f8714dd8dba20a
Publikováno v:
Molecules, Vol 27, Iss 4, p 1304 (2022)
Diels–Alder cycloaddition reaction is one of the most powerful strategies for the construction of six-membered carbocyclic and heterocyclic systems, in most cases with high regio- and stereoselectivity. In this review, an insight into the most rele
Externí odkaz:
https://doaj.org/article/83bbbd3b2eca48b3b3e1b011944da7a0
Autor:
Neuza Domingues, André R. A. Marques, Rita Diogo Almeida Calado, Inês S. Ferreira, Cristiano Ramos, José Ramalho, Maria I. L. Soares, Telmo Pereira, Luís Oliveira, José R. Vicente, Louise H. Wong, Inês C. M. Simões, Teresa M. V. D. Pinho e Melo, Andrew Peden, Cláudia Guimas Almeida, Clare E. Futter, Rosa Puertollano, Winchil L. C. Vaz, Otília V. Vieira
Publikováno v:
Traffic.
Autor:
Neuza Domingues, Joana Gaifem, Rune Matthiesen, Diana P. Saraiva, Luís Bento, André R.A. Marques, Maria I. L. Soares, Julio Sampaio, Christian Klose, Michal A. Surma, Manuel S. Almeida, Gustavo Rodrigues, Pedro Araújo Gonçalves, Jorge Ferreira, Ryan Gouveia e Melo, Luís Mendes Pedro, Kai Simons, Teresa M. V. D. Pinho e Melo, M. Guadalupe Cabral, Antonio Jacinto, Ricardo Silvestre, Winchil Vaz, Otília V. Vieira
Oxidation of polyunsaturated fatty acids (PUFA) in low-density lipoproteins (LDL) trapped in the arterial intima plays a critical role in atherosclerosis. Though there have been many studies on the atherogenicity of oxidized derivatives of unsaturate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fed33e6e31e3b082f7491a1e04b301c5
https://doi.org/10.1101/2023.02.09.527823
https://doi.org/10.1101/2023.02.09.527823
Publikováno v:
Advanced Synthesis & Catalysis. 363:2464-2501
Publikováno v:
Organic Chemistry Frontiers. 8:3543-3593
Spiro-γ-lactams (spiropyrrolidin-2-ones) are a class of spirocyclic compounds that are present in a wide range of synthetic bioactive and naturally occurring molecules. The increasing attention to spirocyclic lactams in drug discovery has been accom
Autor:
Maria I. L. Soares, Clara S. B. Gomes, M. Conceição Oliveira, Teresa M. V. D. Pinho e Melo, Joaquim Marçalo
Publikováno v:
Organic & Biomolecular Chemistry. 19:9711-9722
The DABCO-catalyzed [3 + 3] annulation between 3-nitro-2H-chromenes and benzyl 2,3-butadienoate has been developed as a route to 5H-chromeno[3,4-b]pyridine derivatives. Under optimal reaction conditions, 5H-chromeno[3,4-b]pyridines incorporating two
Autor:
Maria I L, Soares, Clara S B, Gomes, M Conceição, Oliveira, Joaquim, Marçalo, Teresa M V D, Pinho E Melo
Publikováno v:
Organicbiomolecular chemistry. 19(44)
The DABCO-catalyzed [3 + 3] annulation between 3-nitro-2
Autor:
Catarina S. Lopes, Liliana S. Alves, Filomena A. Carvalho, Otilia V. Vieira, André R A Marques, Nuno Padrão, Nuno C. Santos, José S. Ramalho, Teresa M. V. D. Pinho e Melo, Maria I. L. Soares, Clare E. Futter
Publikováno v:
Journal of Cell Science. 135
In atherosclerotic lesions, vascular smooth muscle cells (VSMCs) represent half of the foam cell population, which is characterized by an aberrant accumulation of undigested lipids within lysosomes. Loss of lysosome function impacts VSMC homeostasis