Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Maria I. Chianese"'
Autor:
Maria Rita Milone, Biagio Pucci, Alessandra Leone, Michele Caraglia, Maria I. Chianese, Renato Franco, Alfredo Budillon, Francesca Bruzzese, E. Di Gennaro, Monia Rocco, Daniele Santini, Claudio Arra, Chiara Ciardiello, Antonio Luciano
Publikováno v:
Cell Death & Disease
Patients with advanced prostate cancer (PCa) and multiple myeloma (MM) have limited long-term responses to available therapies. The histone deacetylase inhibitor panobinostat has shown significant preclinical and clinical anticancer activity in both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7c08f278ee82ab44b79d74dbe727b4d
http://hdl.handle.net/11591/184192
http://hdl.handle.net/11591/184192
Autor:
Antonio Luciano, Renato Franco, A Di Cintio, Maria I. Chianese, I de Ruggiero, Francesca Bruzzese, E. Di Gennaro, Geny Piro, Alfredo Budillon, A. Avallone, Claudio Arra, Tania Moccia
Publikováno v:
British Journal of Cancer
Background: Potentiation of anticancer activity of capecitabine is required to improve its therapeutic index. In colorectal cancer (CRC) cells, we evaluated whether the histone deacetylase-inhibitor vorinostat may induce synergistic antitumour effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ca22b7074d819ef072487088c811312
https://pubmed.ncbi.nlm.nih.gov/21045833
https://pubmed.ncbi.nlm.nih.gov/21045833
Autor:
Alessandra Di Cintio, Geny Piro, Alfredo Budillon, Elena Di Gennaro, Francesca Bruzzese, Maria I. Chianese
Publikováno v:
Cancer Research. 71:3519-3519
Capecitabine is a pro-drug which was designed to take advantage of the increased levels of thymidine phosphorylase (TP), a key enzyme for its conversion to 5-florouracil (5-FU), observed in tumours as opposed to normal tissues, potentially allowing f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1729dfda79ae8f08c556a2d1415f766e
https://doi.org/10.1158/1538-7445.am2011-3519
https://doi.org/10.1158/1538-7445.am2011-3519
Autor:
Alessandra Leone, Secondo Lastoria, Alfredo Budillon, Paolo Delrio, Rosario Vincenzo Iaffaioli, Elena Di Gennaro, Luigi Aloi, Antonio Avallone, Maria I. Chianese, Pasquale Comella, Corradina Caracò, Biagio Pecori
Publikováno v:
Cancer Research. 70:3721-3721
Vascular endothelial growth factor (VEGF) has a crucial role in tumor angiogenesis, and its inhibition by bevacizumab (BEV) leads to normalization of tumor vessels increasing tumor oxygenation and drug delivery. However, the clinical benefits of curr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d57b6d4ee47f0f49ea5ab1ac17f530ee
https://doi.org/10.1158/1538-7445.am10-3721
https://doi.org/10.1158/1538-7445.am10-3721
Autor:
Antonio Luciano, Geny Piro, Alfredo Budillon, Francesca Bruzzese, Alessandra Di Cintio, Claudio Arra, Maria I. Chianese, Tania Moccia, Elena Di Gennaro
Publikováno v:
Cancer Research. 70:5442-5442
The oral fluoropyrimidine capecitabine is converted to the active compound 5-florouracil (5-FU) in several steps, the last of which is the conversion of 5′-deoxy-5-fluorouridine (5′DFUR) to 5-FU by thymidine phosphorylase (TP). Capecitabine was d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da5838c94644684316f2c6ef7887e951
https://doi.org/10.1158/1538-7445.am10-5442
https://doi.org/10.1158/1538-7445.am10-5442