Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Maria I. Bergamasco"'
Autor:
Andrew J. Kueh, Maria I. Bergamasco, Anna Quaglieri, Belinda Phipson, Connie S.N. Li-Wai-Suen, Ingrid M. Lönnstedt, Yifang Hu, Zhi-Ping Feng, Chris Woodruff, Rose E. May, Stephen Wilcox, Alexandra L. Garnham, Michael P. Snyder, Gordon K. Smyth, Terence P. Speed, Tim Thomas, Anne K. Voss
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 111980- (2023)
Summary: In the conventional model of transcriptional activation, transcription factors bind to response elements and recruit co-factors, including histone acetyltransferases. Contrary to this model, we show that the histone acetyltransferase KAT7 (H
Externí odkaz:
https://doaj.org/article/4b0b1023c1f947b38cbb26ac1b1ba97c
Autor:
Farrah El-Saafin, Maria I. Bergamasco, Yunshun Chen, Rose E. May, Prabagaran Esakky, Soroor Hediyeh-zadeh, Mathew Dixon, Stephen Wilcox, Melissa J. Davis, Andreas Strasser, Gordon K. Smyth, Tim Thomas, Anne K. Voss
Publikováno v:
Cell Death Differ
Mutations in genes encoding general transcription factors cause neurological disorders. Despite clinical prominence, the consequences of defects in the basal transcription machinery during brain development are unclear. We found that loss of the TATA
Autor:
Helen M. McRae, Ian P. Street, John D. Bentley, Edwin D. Hawkins, Brandon J. Aubrey, Karen L. White, Bin Ren, Matthew L. Dennis, Meghan Hattarki, Stephen Mieruszynski, Natasha Zamudio, Gordon K. Smyth, M.C. Chung, Andrew J. Sealey, Maria I. Bergamasco, Guido Pacini, Natalie L. Downer, Jonathan B. Baell, Andreas Strasser, Jai Rautela, Ricky W. Johnstone, Nghi H. Nguyen, Alexandra L. Garnham, Bilal N. Sheikh, Andrea Newbold, Gemma L. Kelly, David J. Leaver, Pat Pilling, Rose E. May, Nicholas D. Huntington, Johannes Wichmann, Yuquing Yang, Tim Thomas, S.J. Hermans, Hannah K. Vanyai, Anne K. Voss, Beinan Wang, H. Rachel Lagiakos, Brendon J. Monahan, Bethany K. Davey, Stephen Wilcox, Melanie de Silva, Olan Dolezal, Michael W. Parker, Susan A. Charman, Margs S. Brennan, Kimberly J. Morgan, Karen Doggett, Joan K. Heath, Thomas S. Peat, Benjamin Cleary, Hendrik Falk
Publikováno v:
Nature. 560:253-257
Acetylation of histones by lysine acetyltransferases (KATs) is essential for chromatin organization and function1. Among the genes coding for the MYST family of KATs (KAT5-KAT8) are the oncogenes KAT6A (also known as MOZ) and KAT6B (also known as MOR