Výsledky vyhledávání - "Maria I. Albarran"

Legends supplementary Figures 1-6 from Exome Sequencing of Plasma DNA Portrays the Mutation Landscape of Colorectal Cancer and Discovers Mutated VEGFR2 Receptors as Modulators of Antiangiogenic Therapies

Legends for Supplementary Figures 1-6

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bd4e5e8a1416dde19adba9169bae983
https://doi.org/10.1158/1078-0432.22474719

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Table S3 from Exome Sequencing of Plasma DNA Portrays the Mutation Landscape of Colorectal Cancer and Discovers Mutated VEGFR2 Receptors as Modulators of Antiangiogenic Therapies

Table S3: Treatment regimens of the Avatar patient derived xenograft models carrying the VEGFR2 WT and L840F genotypes.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e5b1ffda916b06e2af3d75c14ab922c
https://doi.org/10.1158/1078-0432.22474704.v1

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Figure S2 from Exome Sequencing of Plasma DNA Portrays the Mutation Landscape of Colorectal Cancer and Discovers Mutated VEGFR2 Receptors as Modulators of Antiangiogenic Therapies

Figure S2: Read alignments from WES-cfDNA, showing somatic mutations in APC and TP53 genes.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bad121a403acc5b53cd2610053591c1
https://doi.org/10.1158/1078-0432.22474734.v1

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Online Methods from Exome Sequencing of Plasma DNA Portrays the Mutation Landscape of Colorectal Cancer and Discovers Mutated VEGFR2 Receptors as Modulators of Antiangiogenic Therapies

Detailed methods

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7665c3e5a4f0895b2097985fcf925e74
https://doi.org/10.1158/1078-0432.22474716.v1

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Akademický článek

Fragment-hopping-based discovery of a novel chemical series of proto-oncogene PIM-1 kinase inhibitors.

Autor: Gustavo Saluste, Maria I Albarran, Rosa M Alvarez, Obdulia Rabal, Miguel Angel Ortega, Carmen Blanco, Guido Kurz, Antonio Salgado, Paolo Pevarello, James R Bischoff, Joaquin Pastor, Julen Oyarzabal

Publikováno v: PLoS ONE, Vol 7, Iss 10, p e45964 (2012)

A new chemical series, triazolo[4,5-b]pyridines, has been identified as an inhibitor of PIM-1 by a chemotype hopping strategy based on a chemically feasible fragment database. In this case, structure-based virtual screening and in silico chemogenomic

Externí odkaz: https://doaj.org/article/1991fa60141b408181e69602e550bc26

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