Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Maria I Sierra"'
Autor:
Mattias Magnusson, Maria I Sierra, Rajkumar Sasidharan, Sacha L Prashad, Melissa Romero, Pamela Saarikoski, Ben Van Handel, Andy Huang, Xinmin Li, Hanna K A Mikkola
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53912 (2013)
Lack of HLA-matched hematopoietic stem cells (HSC) limits the number of patients with life-threatening blood disorders that can be treated by HSC transplantation. So far, insufficient understanding of the regulatory mechanisms governing human HSC has
Externí odkaz:
https://doaj.org/article/0b8c4615dcdf4df7995130c53d242d9c
Autor:
Maria I Sierra, Sridhar Duvvuri, John J. Renger, David J. Stone, Rahul Sasane, Amy Bartels, Michelle Field, David Gray, Sokhom S Pin
Publikováno v:
J Clin Invest
BACKGROUNDRecently the α1 adrenergic receptor antagonist terazosin was shown to activate PGK1, a possible target for the mitochondrial deficits in Parkinson disease related to its function as the initial enzyme in ATP synthesis during glycolysis. An
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33f28d3c8b986f5a330171e736d0d368
https://pubmed.ncbi.nlm.nih.gov/34060482
https://pubmed.ncbi.nlm.nih.gov/34060482
Autor:
Diana R. Dou, Vincenzo Calvanese, Maria I. Sierra, Andrew T. Nguyen, Arazin Minasian, Pamela Saarikoski, Rajkumar Sasidharan, Christina M. Ramirez, Jerome A. Zack, Gay M. Crooks, Zoran Galic, Hanna K. A. Mikkola
Publikováno v:
Nature cell biology, vol 18, iss 6
Nature cell biology
Nature cell biology
Pluripotent stem cells (PSCs) may provide a potential source of haematopoietic stem/progenitor cells (HSPCs) for transplantation; however, unknown molecular barriers prevent the self-renewal of PSC-HSPCs. Using two-step differentiation, human embryon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0a86bfafe146ff7652fa83537716fe7
https://escholarship.org/uc/item/7428v8mq
https://escholarship.org/uc/item/7428v8mq
Publikováno v:
Journal of Biological Chemistry. 285:37895-37908
Reversible ubiquitination orchestrated by the opposition of ubiquitin ligases and deubiquitinating enzymes mediates endocytic trafficking of cell surface receptors for lysosomal degradation. Ubiquitin-specific protease 8 (USP8) has previously been im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eea1a11e3d6b70f84b1471c0d1559316
https://doi.org/10.1074/jbc.m110.129411
https://doi.org/10.1074/jbc.m110.129411
Publikováno v:
Journal of Biological Chemistry. 285:13990-14004
Reversible ubiquitination is essential for the endocytic sorting and down-regulation of G protein-coupled receptors, such as the chemokine receptor CXCR4. The deubiquitinating enzyme AMSH has been implicated in the endocytic sorting of both G protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d619c424c55f347b44069b6e758c08b
https://doi.org/10.1074/jbc.m109.061309
https://doi.org/10.1074/jbc.m109.061309
Autor:
Diana R. Dou, Vincenzo Calvanese, Maria I. Sierra, Rajkumar Sasidharan, Jerome A. Zack, Gay M. Crooks, Zoran Galic, Hanna Mikkola
Publikováno v:
ResearcherID
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27744623a3d53363f4069962faf1ed18
https://doi.org/10.1016/j.exphem.2015.06.064
https://doi.org/10.1016/j.exphem.2015.06.064
Autor:
Hanna K. A. Mikkola, Maria I. Sierra, Matthias Magnusson, Sacha L. Prashad, Vincenzo Calvanese
Publikováno v:
Experimental Hematology. 42:S27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b02ee25caa1922afd4ae5573bdff233
https://doi.org/10.1016/j.exphem.2014.07.094
https://doi.org/10.1016/j.exphem.2014.07.094
Autor:
Xin-Min Li, Maria I. Sierra, Andy Huang, Hanna K. A. Mikkola, Melissa Romero, Ben Van Handel, Sacha L. Prashad, Rajkumar Sasidharan, Mattias Magnusson, Pamela Saarikoski
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53912 (2013)
PLoS ONE
PLoS ONE
Lack of HLA-matched hematopoietic stem cells (HSC) limits the number of patients with life-threatening blood disorders that can be treated by HSC transplantation. So far, insufficient understanding of the regulatory mechanisms governing human HSC has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80eead7bd0b65cc34cf304a112a763d4
https://doi.org/10.1371/journal.pone.0053912
https://doi.org/10.1371/journal.pone.0053912
Autor:
Diana R Dou, Arazin Minasian, Maria I Sierra, Pamela Saarikoski, Jian Xu, Stuart H. Orkin, Sacha L. Prashad, Mattias Magnusson, Jerome A. Zack, Gay M. Crooks, Zoran Galic, Hanna K. A. Mikkola
Publikováno v:
Blood. 120:1190-1190
Abstract 1190 The inability to derive functional hematopoietic stem cells (HSCs) in vitro from pluripotent cells prevents widespread utilization of HSCs in the clinic; however, the molecular defects compromising the in vitro generated hematopoietic s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::360bac5ebf49a962fbbbe736b1ddd76f
https://doi.org/10.1182/blood.v120.21.1190.1190
https://doi.org/10.1182/blood.v120.21.1190.1190