Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Maria I Nunez"'
Autor:
Charles Lu, David J Stewart, J Jack Lee, Lin Ji, Rajagopal Ramesh, Gitanjali Jayachandran, Maria I Nunez, Ignacio I Wistuba, Jeremy J Erasmus, Marshall E Hicks, Elizabeth A Grimm, James M Reuben, Veerabhadran Baladandayuthapani, Nancy S Templeton, John D McMannis, Jack A Roth
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34833 (2012)
Tumor suppressor gene TUSC2/FUS1 (TUSC2) is frequently inactivated early in lung cancer development. TUSC2 mediates apoptosis in cancer cells but not normal cells by upregulation of the intrinsic apoptotic pathway. No drug strategies currently exist
Externí odkaz:
https://doaj.org/article/eb78a39f4a0d4587ba18e50d4d831184
Autor:
William W Lockwood, Ian M Wilson, Bradley P Coe, Raj Chari, Larissa A Pikor, Kelsie L Thu, Luisa M Solis, Maria I Nunez, Carmen Behrens, John Yee, John English, Nevin Murray, Ming-Sound Tsao, John D Minna, Adi F Gazdar, Ignacio I Wistuba, Calum E MacAulay, Stephen Lam, Wan L Lam
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37775 (2012)
For therapeutic purposes, non-small cell lung cancer (NSCLC) has traditionally been regarded as a single disease. However, recent evidence suggest that the two major subtypes of NSCLC, adenocarcinoma (AC) and squamous cell carcinoma (SqCC) respond di
Externí odkaz:
https://doaj.org/article/c1237f92425b4c769e46735d12ff1985
Autor:
C. Marcelo Aldaz, Aysegul Sahin, Steve Horvath, Tao Shi, Sally Gaddis, Maria I. Nunez, Yuhui Hu, Jeffrey A. Drake, Kathleen A. Hawkins, Hongxia Sun, Martín C. Abba
Supplementary Table S1 from Breast Cancer Molecular Signatures as Determined by SAGE: Correlation with Lymph Node Status
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0892f94135b47c8fa62073a44bbc823e
https://doi.org/10.1158/1541-7786.22520764
https://doi.org/10.1158/1541-7786.22520764
Autor:
C. Marcelo Aldaz, Aysegul Sahin, Steve Horvath, Tao Shi, Sally Gaddis, Maria I. Nunez, Yuhui Hu, Jeffrey A. Drake, Kathleen A. Hawkins, Hongxia Sun, Martín C. Abba
Global gene expression measured by DNA microarray platforms have been extensively used to classify breast carcinomas correlating with clinical characteristics, including outcome. We generated a breast cancer Serial Analysis of Gene Expression (SAGE)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2031e37a73b8b25f1ebd6381dfa275e
https://doi.org/10.1158/1541-7786.c.6542758.v1
https://doi.org/10.1158/1541-7786.c.6542758.v1
Autor:
Monique B. Nilsson, John V. Heymach, Reza J. Mehran, Brett W. Carter, Ignacio I. Wistuba, Lixia Diao, Maria I. Nunez, Jing Wang, Youhong Fan, J. Jack Lee, Heather Lin, Junya Fujimoto, Anne S. Tsao, S.G. Swisher, Ara Vaporcyan, David C. Rice, Waun Ki Hong
Publikováno v:
Journal of Thoracic Oncology. 13:246-257
Introduction Window of opportunity trials in malignant pleural mesothelioma (MPM) are challenging but can yield important translational information about a novel agent. Methods We treated patients with MPM (N = 24) with 4 weeks of oral dasatinib foll
Autor:
Jeffrey N. Myers, Maria I. Nunez, Bonnie S. Glisson, William N. William, Renata Ferrarotto, Ignacio I. Wistuba, J. Jack Lee, Nusrat Harun, Mohammad Y. Ibrahim, Adel K. El-Naggar
Publikováno v:
Headneck. 41(3)
Background This study investigated the hypothesis that phosphoinositide 3-kinase (PI3-kinase) pathway dysregulation in either head and neck cancer cells and/or tumor infiltrating immune cells would influence outcomes of patients with surgically treat
Autor:
Wadih Arap, Martin J. Edelman, Andrew Bradbury, Daniel F. Cimino, Maria I. Nunez, Ming D. Qian, Julianna K. Edwards, Ignacio I. Wistuba, Andrey S. Dobroff, Ximing Tang, Fortunato Ferrara, Roy R. Lobb, Waun Ki Hong, Richard L. Sidman, Fernanda I. Staquicini, Renata Pasqualini, Diane D. Liu, J. Jack Lee, Patrick J. Kelly, Ahmad Salameh, Benjamin J. Moeller
Publikováno v:
The Journal of Biological Chemistry
Background: EphA5 is a functional target in lung cancer, the most common cause of tumor-related death in mankind. Results: EphA5 regulates cell cycle checkpoints and DNA damage repair induced by ionizing radiation. Conclusion: EphA5 is a novel regula
Autor:
R. Mehran, Cesar A. Moran, Lixia Diao, Harvey I. Pass, Amin Momin, David C. Rice, Ignacio I. Wistuba, Gabriela Raso, J. Wang, Chi-Wan Chow, Milind Suraokar, Maria I. Nunez, Carmen Behrens, Brian P. James, D. U. Kim, Anne Tsao, H. Lin, Ji-Sun Lee, Se-Hoon Lee, Alejandro H. Corvalan, Kevin R. Coombes
Publikováno v:
Annals of Oncology. 25:1184-1192
1. International Agency for Research on Cancer, World Health Organization. Estimatedcancer Incidence, Mortality, Prevalence and Disability-adjusted life years (DALYs)Worldwide in2008. http://globocan.iarc.fr/(17August2013,datelastaccessed).2. Vital S
Autor:
Carmen Behrens, Stephen G. Swisher, Diane Liu, Yan Heather Lin, J. Jack Lee, John V. Heymach, Ignacio I. Wistuba, Maria I. Nunez, Waun Ki Hong, Jack A. Roth, David J. Stewart
Publikováno v:
Journal of Thoracic Oncology. 9:675-684
Background: Adjuvant chemotherapy reduces recurrences of non–small-cell lung cancer (NSCLC). To determine which patients need adjuvant chemotherapy, we assessed factors associated with time to relapse (TTR). Methods: In 230 resected stage I–II NS
Autor:
Ruping Shao, Maria I. Nunez, Maria Gabriela Raso, Stephen G. Swisher, Ignacio I. Wistuba, Bingliang Fang, Ludmila Prudkin, Luisa M. Solis, Faye M. Johnson, Carmen Behrens, Chengcheng Guo, Arlene M. Correa, Jack A. Roth, Tongyu Lin, Apar Pataer
Publikováno v:
Journal of Thoracic Oncology. 8:301-308
IntroductionRNA-dependent protein kinase (PKR) is an independent prognostic variable in patients with non–small-cell lung cancer (NSCLC). In the current study, we investigated the correlation between PKR and 25 other biomarkers for NSCLC, identifie