Zobrazeno 1 - 4
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pro vyhledávání: '"Maria Hosseinipour"'
Autor:
Kim E. Creek, Phillip Buckhaults, Maria Hosseinipour, Fadi F. Abboodi, Lucia Pirisi, Carolyn E. Banister, Changlong Liu, Diego Altomare
Publikováno v:
Virology. 554:9-16
HPV-inactive head and neck and cervical cancers contain HPV DNA but do not express HPV E6/E7. HPV-positive primary head and neck tumors usually express E6/E7, however they may produce HPV-inactive metastases. These observations led to our hypothesis
Publikováno v:
Virology
The homeodomain transcription factor SIX1 plays a critical role in embryogenesis, is not expressed in normal adult tissue, but is expressed in many malignancies, including cervical cancer. SIX1 drives the progression of HPV16-immortalized human kerat
Publikováno v:
Journal of Virology. 92
Human papillomavirus (HPV) infection of the genital tract is common; however, only about 10 to 15% of infections persist, and approximately 10 to 15% of these persistent infections result in cancer. Basal epidermal stem cells are the presumed target
Publikováno v:
Cancer Research. 76:2025-2025
SIX1, a homeodomain-containing transcription factor, has a critical role in the expansion of progenitor cells during embryogenesis. The overexpression of SIX1 contributes to tumorigenesis, promoting malignant transformation and metastasis. Six1 promo