Cognitive Change During the Life Course and Leukocyte Telomere Length in Late Middle-aged Men.

Autor: Lene Rask, Laila Bendix, Maria Harbo, Birgitte Fagerlund, Erik Lykke Mortensen, Martin Johannes Laurtizen, Merete Osler

Publikováno v: Frontiers in Aging Neuroscience, Vol 8 (2016)

AbstractImportance: Cognitive skills are known to decline through the lifespan with large individual differences. The molecular mechanisms for this decline are incompletely understood. Although leukocyte telomere length provides an index of cellular

Externí odkaz: https://doaj.org/article/4ec6419f54014bad889f3c3a7a7b7fc4

Pathogenic RBM20-Variants Are Associated With a Severe Disease Expression in Male Patients With Dilated Cardiomyopathy

Autor: Torsten Bloch Rasmussen, Thomas Morris Hey, Mads Malik Aagaard, Trine Madsen, Jens Mogensen, Maria Harbo, Hans Eiskjær, Jacob E. Møller, Henning Mølgaard

Publikováno v: Hey, T M, Rasmussen, T B, Madsen, T, Aagaard, M M, Harbo, M, Mølgaard, H, Møller, J E, Eiskjær, H & Mogensen, J 2019, ' Pathogenic RBM20-Variants Are Associated With a Severe Disease Expression in Male Patients With Dilated Cardiomyopathy ', Circulation. Heart Failure, vol. 12, no. 3, e005700 . https://doi.org/10.1161/CIRCHEARTFAILURE.118.005700
Hey, T M, Rasmussen, T B, Madsen, T, Aagaard, M M, Harbo, M, Mølgaard, H, Møller, J E, Eiskjær, H & Mogensen, J 2019, ' Pathogenic RBM20-variants are associated with a severe disease expression in male patients with dilated cardiomyopathy ', Circulation: Heart Failure, vol. 12, no. 3, e005700 . https://doi.org/10.1161/CIRCHEARTFAILURE.118.005700
Hey, T M, Rasmussen, T B, Madsen, T, Aagaard, M M, Harbo, M, Mølgaard, H, Møller, J E, Eiskjær, H & Mogensen, J 2019, ' Pathogenic RBM20-Variants Are Associated With a Severe Disease Expression in Male Patients With Dilated Cardiomyopathy ', Circulation. Heart Failure, vol. 12, no. 3, e005700, pp. 1-14 . https://doi.org/10.1161/CIRCHEARTFAILURE.118.005700

Background As pathogenic variants in the gene for RBM20 appear with a frequency of 6% among Danish patients with dilated cardiomyopathy (DCM), it was the aim to investigate the associated disease expression in affected families. Methods and Results C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1d16a39346a9968231e4309df0d7af5
https://findresearcher.sdu.dk:8443/ws/files/155849429/Pathogenic_RBM20_variants_are_Associated_With_a_Severe_Disease.pdf

3947Yield of clinical and genetic cascade screening among 436 relatives of 111 consecutive index-patients with dilated cardiomyopathy

Autor: Maria Harbo, Torsten Bloch Rasmussen, Mads Malik Aagaard, Jens Mogensen, H. Moelgaard, Hans Eiskjær, J E Moeller, Trine Madsen, T. Gadgaard, Thomas Morris Hey

Publikováno v: European Heart Journal. 38

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::37a35ea9ea0c9444730ef48d0ea85163
https://doi.org/10.1093/eurheartj/ehx504.3947

Telomere dynamics in human mesenchymal stem cells after exposure to acute oxidative stress

Autor: Steen Koelvraa, Nedime Serakinci, Maria Harbo, Laila Bendix

Publikováno v: Harbo, M, Koelvraa, S, Serakinci, N & Bendix, L 2012, ' Telomere dynamics in human mesenchymal stem cells after exposure to acute oxidative stress ', D N A Repair, vol. 11, no. 9, pp. 774-779 . https://doi.org/10.1016/j.dnarep.2012.06.003

A gradual shortening of telomeres due to replication can be measured using the standard telomere restriction fragments (TRF) assay and other methods by measuring the mean length of all the telomeres in a cell. In contrast, stress-induced telomere sho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaf9433cfadf85f4a1a752702a58db5e
https://doi.org/10.1016/j.dnarep.2012.06.003

Heterogenous mismatch-repair status in colorectal cancer

Autor: Mef Nilbert, Louise Laurberg Klarskov, Eva Rambech, Anders Bojesen, Patrick Joost, Maria Harbo, Nynke Veurink, Susanne Holck, Bo Baldetorp

Publikováno v: Joost, P, Veurink, N, Holck, S, Klarskov, L, Bojesen, A, Harbo, M, Baldetorp, B, Rambech, E & Nilbert, M 2014, ' Heterogenous mismatch-repair status in colorectal cancer ', Diagnostic Pathology, vol. 9, 126, pp. 126 . https://doi.org/10.1186/1746-1596-9-126
Diagnostic Pathology; 9, no 126 (2014)
Diagnostic Pathology

Background Immunohistochemical staining for mismatch repair proteins is efficient and widely used to identify mismatch repair defective tumors. The tumors typically show uniform and widespread loss of MMR protein staining. We identified and character

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e89874a4b5eb2c1b09ba524964e24c3
https://portal.findresearcher.sdu.dk/da/publications/0bb2d8a1-6dc9-4341-bddb-9f988d233d38