Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Maria Guirola"'
Autor:
Lorena Espinar, Marta Garcia-Cao, Alisa Schmidt, Savvas Kourtis, Antoni Gañez Zapater, Carla Aranda-Vallejo, Ritobrata Ghose, Laura Garcia-Lopez, Ilir Sheraj, Natalia Pardo-Lorente, Marina Bantulà, Laura Pascual-Reguant, Evangelia Darai, Maria Guirola, Joan Montero, Sara Sdelci
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Nuclear metabolism and DNA damage response are intertwined processes, but the precise molecular links remain elusive. Here, we explore this crosstalk using triple-negative breast cancer (TNBC) as a model, a subtype often prone to DNA damage
Externí odkaz:
https://doaj.org/article/0fd2c3a7be624c68af7c1b6ba8b07ae7
Autor:
Laura Pascual‐Reguant, Queralt Serra‐Camprubí, Debayan Datta, Damiano Cianferoni, Savvas Kourtis, Antoni Gañez‐Zapater, Chiara Cannatá, Lorena Espinar, Jessica Querol, Laura García‐López, Sara Musa‐Afaneh, Maria Guirola, Anestis Gkanogiannis, Andrea Miró Canturri, Marta Guzman, Olga Rodríguez, Andrea Herencia‐Ropero, Joaquin Arribas, Violeta Serra, Luis Serrano, Tian V Tian, Sandra Peiró, Sara Sdelci
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 12, Pp 1-23 (2023)
Abstract Triple‐negative breast cancer (TNBC) often develops resistance to single‐agent treatment, which can be circumvented using targeted combinatorial approaches. Here, we demonstrate that the simultaneous inhibition of LOXL2 and BRD4 synergis
Externí odkaz:
https://doaj.org/article/a9ac7e4ea8d342f3a90f379ec5eb682e
Publikováno v:
Epigenetics & Chromatin, Vol 12, Iss 1, Pp 1-10 (2019)
Abstract Background In order to prepare the genome for gametogenesis, primordial germ cells (PGCs) undergo extensive epigenetic reprogramming during migration toward the gonads in mammalian embryos. This includes changes on a genome-wide scale and ad
Externí odkaz:
https://doaj.org/article/d2fe76d6069a403b9b4b63897219af71
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43299 (2012)
Non-vertebrate chordates, specifically amphioxus, are considered of the utmost interest for gaining insight into the evolutionary trends, i.e. differentiation and specialization, of gene/protein systems. In this work, MTs (metallothioneins), the most
Externí odkaz:
https://doaj.org/article/dd78a615288946f6ae3d919d66d04113
Autor:
Laura Pascual-Reguant, Tian V. Tian, Debayan Datta, Damiano Cianferoni, Savvas Kourtis, Antoni Gañez-Zapater, Chiara Cannatá, Queralt Serra-Camprubi, Lorena Espinar, Maria Guirola, Jessica Querol, Andrea Miró Canturri, Joaquin Arribas, Luis Serrano, Sandra Peiró, Sara Sdelci
Publikováno v:
Biorxiv.org (submitted to Cancer Reaserch)
bioRxiv
bioRxiv
Triple-negative breast cancer often develops resistance to single-agent treatments, which can be circumvented with targeted combinatorial approaches. Here, we demonstrate that the simultaneous inhibition of LOXL2 and BRD4 cooperate to reduce triple-n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98969a4dc6b42f91b8f7a8a652d043c5