Zobrazeno 1 - 10
of 146
pro vyhledávání: '"Maria Grazia de Simoni"'
Autor:
Evangelia Papadimou, Marina Morigi, Paraskevas Iatropoulos, Christodoulos Xinaris, Susanna Tomasoni, Valentina Benedetti, Lorena Longaretti, Cinzia Rota, Marta Todeschini, Paola Rizzo, Martino Introna, Maria Grazia de Simoni, Giuseppe Remuzzi, Michael S. Goligorsky, Ariela Benigni
Publikováno v:
Stem Cell Reports, Vol 4, Iss 4, Pp 685-698 (2015)
The application of cell-based therapies in regenerative medicine is gaining recognition. Here, we show that human bone marrow stromal cells (BMSCs), also known as bone-marrow-derived mesenchymal cells, can be reprogrammed into renal proximal tubular-
Externí odkaz:
https://doaj.org/article/4b92a72d6f82461589cc7794726f97a2
Publikováno v:
The Scientific World Journal, Vol 9, Pp 891-908 (2009)
Alzheimer's disease (AD) is the leading cause of dementia and cognitive decline in the elderly. Brain tissue changes indicate that the two main proteins involved in AD are amyloid-β(A-β), which is associated with the formation of senile amyloid pla
Externí odkaz:
https://doaj.org/article/a9aaf799a75d4b5081bbc9d680086245
Autor:
Silvia Carloni, Erika Mazzoni, Mauro Cimino, Maria Grazia De Simoni, Carlo Perego, Claudia Scopa, Walter Balduini
Publikováno v:
Neurobiology of Disease, Vol 21, Iss 1, Pp 119-126 (2006)
The present study was undertaken to evaluate whether in a neonatal model of stroke a prophylactic neuroprotective treatment with simvastatin modulates hypoxia–ischemia-induced inflammatory and apoptotic signaling. Procaspase-3 and cleaved caspase-3
Externí odkaz:
https://doaj.org/article/905321f85a4240c08b9d906c59353ace
Autor:
Chiara Pastori, Laura Librizzi, Gian Luca Breschi, Cristina Regondi, Carolina Frassoni, Ferruccio Panzica, Simona Frigerio, Maurizio Gelati, Eugenio Parati, Maria Grazia De Simoni, Marco de Curtis
Publikováno v:
PLoS ONE, Vol 3, Iss 7, p e2754 (2008)
BACKGROUND: Treatment with neural stem cells represents a potential strategy to improve functional recovery of post-ischemic cerebral injury. The potential benefit of such treatment in acute phases of human ischemic stroke depends on the therapeutic
Externí odkaz:
https://doaj.org/article/ee436d8bd361440c9e4eaee13a9d0c12
Autor:
Stefano Fumagalli, Fabio Fiordaliso, Carlo Perego, Alessandro Corbelli, Alessandro Mariani, Massimiliano De Paola, Maria-Grazia De Simoni
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-14 (2019)
Abstract Background Phagocytosis is a key function of myeloid cells and is highly involved in brain ischemic injury. It has been scarcely studied in vivo, thus preventing a deep knowledge of the processes occurring in the ischemic environment. Struct
Externí odkaz:
https://doaj.org/article/59d5a9ddc11143a2aecc5caf2cdd4b62
Autor:
Ersilia Varone, Diego Pozzer, Simona Di Modica, Alexander Chernorudskiy, Leonardo Nogara, Martina Baraldo, Mario Cinquanta, Stefano Fumagalli, Rocio Nur Villar-Quiles, Maria-Grazia De Simoni, Bert Blaauw, Ana Ferreiro, Ester Zito
Publikováno v:
Redox Biology, Vol 24, Iss , Pp - (2019)
Selenoprotein N (SELENON) is an endoplasmic reticulum (ER) protein whose loss of function leads to a congenital myopathy associated with insulin resistance (SEPN1-related myopathy). The exact cause of the insulin resistance in patients with SELENON l
Externí odkaz:
https://doaj.org/article/73fb0f5074fc465186227627ec912a26
Autor:
Cecilia Garlanda, Stefano Fumagalli, Agata Ciechanowska, Marco Oggioni, Carlo Perego, Maria Grazia De Simoni, Daiana De Blasio, Stefania Ippati, Denise Minuta, Marina Sironi, Katarzyna Popiolek-Barczyk, Joanna Mika, Domenico Mercurio
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Scientific Reports
Scientific Reports
Long pentraxin PTX3, a pattern recognition molecule involved in innate immune responses, is upregulated by pro-inflammatory stimuli, contributors to secondary damage in traumatic brain injury (TBI). We analyzed PTX3 involvement in mice subjected to c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5031c64a8c05f9eafb54ff982c664b5
https://doaj.org/article/ab84c6e775b8498fa19cd39f64b559e4
https://doaj.org/article/ab84c6e775b8498fa19cd39f64b559e4
Autor:
Pier Luigi Meroni, Maria Orietta Borghi, Paola Adele Lonati, Maria Grazia De Simoni, Francesco Tedesco, Marco Oggioni, Laura Neglia, Claudia Grossi, Stefano Fumagalli, Carolina Artusi
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism
Beta-2 Glycoprotein I (β2-GPI) is the main target of anti-phospholipid antibodies (aPL) in the autoimmune anti-phospholipid syndrome, characterized by increased risk of stroke. We here investigated the antibody independent role of β2-GPI after isch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0ff9fbcc1bef5ec89bf399bab45b99f
http://europepmc.org/articles/PMC8323337
http://europepmc.org/articles/PMC8323337
Autor:
Maria Grazia De Simoni, Katarzyna Popiolek-Barczyk, Marco Oggioni, Joanna Mika, Domenico Mercurio, Katarzyna Pawlik, Agata Ciechanowska, Katarzyna Ciapała
Publikováno v:
Pharmacological Reports
Background Every year, millions of people suffer from various forms of traumatic brain injury (TBI), and new approaches with therapeutic potential are required. Although chemokines are known to be involved in brain injury, the importance of X-C motif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::537914962950dc89283e1f786e92b39b
http://europepmc.org/articles/PMC7704520
http://europepmc.org/articles/PMC7704520
Autor:
Domenico Mercurio, Stefano Fumagalli, Martin K-H Schafer, Jordi Pedragosa, Lionel Dejeumen Claude Ngassam, Verena Wilhelmi, Sarah Winterberg, Anna M. Planas, Eberhard Weihe, Maria-Grazia De Simoni
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
The activation of microglia and the infiltration of macrophages are hallmarks of neuroinflammation after acute brain injuries, including traumatic brain injury (TBI). The two myeloid populations share many features in the post-injury inflammatory res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0e8f9cf8a5838ded1ea33b8b60dca68
https://pubmed.ncbi.nlm.nih.gov/35221925
https://pubmed.ncbi.nlm.nih.gov/35221925