Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Maria Grazia Rizzetti"'
Autor:
Mara Mazzoni, Giuseppe Mauro, Marco Erreni, Paola Romeo, Emanuela Minna, Maria Grazia Vizioli, Cristina Belgiovine, Maria Grazia Rizzetti, Sonia Pagliardini, Roberta Avigni, Maria Chiara Anania, Paola Allavena, Maria Grazia Borrello, Angela Greco
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-16 (2019)
Abstract Background Thyroid carcinoma includes several variants characterized by different biological and clinical features: from indolent microcarcinoma to undifferentiated and aggressive anaplastic carcinoma. Inflammation plays a critical role in t
Externí odkaz:
https://doaj.org/article/95caeb225f714bf98d84e023062636ff
Autor:
Mara Mazzoni, Giuseppe Mauro, Lucia Minoli, Loredana Cleris, Maria Chiara Anania, Tiziana Di Marco, Emanuela Minna, Sonia Pagliardini, Maria Grazia Rizzetti, Giacomo Manenti, Maria Grazia Borrello, Eugenio Scanziani, Angela Greco
Publikováno v:
Biology, Vol 10, Iss 10, p 985 (2021)
Inflammation plays a critical role in thyroid cancer onset and progression. We previously characterized the in vitro interplay between macrophages and senescent human thyrocytes and thyroid tumor-derived cell lines, modeling the early and the late th
Externí odkaz:
https://doaj.org/article/0d5dbd5589cf43b48a3b3982bb5483cf
Autor:
Eugenio Scanziani, Loredana Cleris, Maria Grazia Borrello, Sonia Pagliardini, Angela Greco, Maria Grazia Rizzetti, Giacomo Manenti, Maria Chiara Anania, Giuseppe Di Mauro, Mara Mazzoni, Tiziana Di Marco, Emanuela Minna, Lucia Minoli
Publikováno v:
Biology
Biology, Vol 10, Iss 985, p 985 (2021)
Biology, Vol 10, Iss 985, p 985 (2021)
Simple Summary Several studies including ours suggest a pro-tumoral role of senescent thyrocytes in thyroid tumors. On the other hand, M2-like tumor associated macrophages infiltration increases with thyroid cancer aggressiveness. In this work, we us
Autor:
Loris De Cecco, Elisa Bonaldi, Emanuela Minna, Arianna Micali, Angela Greco, Maria Grazia Rizzetti, Maria Grazia Borrello, Chiara Gargiuli
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5744, p 5744 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 11
International Journal of Molecular Sciences
Volume 22
Issue 11
BRAFV600E is the most frequent oncogenic mutation identified in papillary thyroid cancer (PTC). In PTC patients who do not respond to standard treatment, BRAF inhibitors are currently tested as alternative strategies. However, as observed for other t
Autor:
Maria Grazia Borrello, Roberta Avigni, Paola Romeo, Emanuela Minna, Maria Chiara Anania, Angela Greco, Maria Grazia Rizzetti, Cristina Belgiovine, Sonia Pagliardini, Paola Allavena, Maria Grazia Vizioli, Giuseppe Di Mauro, Mara Mazzoni, Marco Erreni
Publikováno v:
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-16 (2019)
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-16 (2019)
Background Thyroid carcinoma includes several variants characterized by different biological and clinical features: from indolent microcarcinoma to undifferentiated and aggressive anaplastic carcinoma. Inflammation plays a critical role in thyroid tu
Autor:
Laura D. Locati, Ambra Vittoria Gualeni, Giuseppina Calareso, Matteo Dugo, Carla Colombo, Angela Zanframundo, Antonella Aiello, Paola Romeo, Loris De Cecco, Lisa Licitra, Maria Grazia Borrello, Laura Fugazzola, Angela Greco, Maria Grazia Rizzetti, Annunziata Gloghini, Stefano Ferrero, Roberta Granata, Maria Luisa Carcangiu
Publikováno v:
Endocrine-related cancer. 25(3)
This study aimed to identify circulating miRNAs as novel non-invasive biomarkers for prognosis and vandetanib response in advanced medullary thyroid cancer (MTC) patients. We prospectively recruited two independent cohorts of locally advanced/metasta
Autor:
A Fiorino, M.A. Pierotti, Maria Grazia Borrello, Maria Grazia Rizzetti, Claudia Miranda, S Donatello, Italia Bongarzone, Luisella Alberti, L. Gorla, Debora Degl'Innocenti
Publikováno v:
Oncogene. 26:6546-6559
The RET gene encodes two main isoforms of a receptor tyrosine kinase (RTK) implicated in various human diseases. Activating germ-line point mutations are responsible for multiple endocrine neoplasia type 2-associated medullary thyroid carcinomas, ina
Autor:
Angela Greco, Maria Grazia Rizzetti, Marco A. Pierotti, Carla Colombo, Laura Fugazzola, Daniele Lecis, Paola Romeo, Maria Grazia Borrello, Piera Mondellini, Emanuela Minna, Luca Persani
Publikováno v:
Orphanet Journal of Rare Diseases
Background Hereditary medullary thyroid carcinoma (MTC) is caused by germ-line gain of function mutations in the RET proto-oncogene, and a phenotypic variability among carriers of the same mutation has been reported. We recently observed this phenome
Autor:
Maria Grazia Borrello, Piera Mondellini, Angela Greco, Maria Grazia Rizzetti, Antonella Aiello, Ettore Seregni, Debora Degl'Innocenti, Italia Bongarzone, Paola Collini, Veronica Catalano, Marco A. Pierotti, Bernard Peissel, Morena Gobbo
Publikováno v:
Endocrine-related cancer. 18(4)
Activating mutations of RET, a gene encoding two isoforms of a tyrosine kinase receptor physiologically expressed in several neural crest-derived cell lineages, are associated with the inherited forms of medullary thyroid carcinoma (MTC). The identif
Autor:
Luisella Alberti, Elena Arighi, Cristina Ferrario, Maria Grazia Rizzetti, Romina Sangregorio, Maria Grazia Borrello, Marco A. Pierotti, Debora Degl'Innocenti, Hannu Sariola, Anna E. Popsueva
Publikováno v:
Oncogene. 23(44)
The receptor tyrosine kinase RET is alternatively spliced to yield two main isoforms, RET9 and RET51, which differ in their carboxyl terminal. Activated RET induces different biological responses such as morphological transformation, neurite outgrowt