Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Maria Grazia Lain"'
Autor:
Lesley R. de Armas, Vinh Dinh, Akshay Iyer, Suresh Pallikkuth, Rajendra Pahwa, Nicola Cotugno, Stefano Rinaldi, Paolo Palma, Paula Vaz, Maria Grazia Lain, Savita Pahwa
Publikováno v:
iScience, Vol 27, Iss 5, Pp 109720- (2024)
Summary: In perinatal HIV infection, early antiretroviral therapy (ART) initiation is recommended but questions remain regarding infant immune responses to HIV and its impact on immune development. Using single cell transcriptional and phenotypic ana
Externí odkaz:
https://doaj.org/article/f4de541eeec74b8e95586b91e5b426a7
Autor:
Catherine K. Koofhethile, Stefano Rinaldi, Yelizaveta Rassadkina, Vinh B. Dinh, Ce Gao, Suresh Pallikkuth, Pilar Garcia-Broncano, Lesley R. de Armas, Rajendra Pahwa, Nicola Cotugno, Paula Vaz, Maria Grazia Lain, Paolo Palma, Xu G. Yu, Roger Shapiro, Savita Pahwa, Mathias Lichterfeld
Publikováno v:
International Journal of Infectious Diseases, Vol 127, Iss , Pp 129-136 (2023)
Background: The persistence of HIV-1-infected cells during antiretroviral therapy is well documented but may be modulated by early initiation of antiretroviral therapy in infants. Methods: Here, we longitudinally analyzed the proviral landscape in ni
Externí odkaz:
https://doaj.org/article/b06f070939f546db9fa6cb765ce143d2
Autor:
Nicola Cotugno, Suresh Pallikkuth, Marco Sanna, Vinh Dinh, Lesley de Armas, Stefano Rinaldi, Sheldon Davis, Giulia Linardos, Giuseppe Rubens Pascucci, Rajendra Pahwa, Nadia Sitoe, Paula Vaz, Paolo Rossi, Maria Grazia Lain, Paolo Palma, Savita Pahwa
Publikováno v:
EBioMedicine, Vol 93, Iss , Pp 104666- (2023)
Summary: Background: Despite antiretroviral treatment (ART), immune dysfunction persists in children with perinatal HIV infection (HEI). Here we investigated the impact of HIV status on maternal antibody (Ab) passage, long-term vaccine induced immuni
Externí odkaz:
https://doaj.org/article/0c700295272447709a4fffae25cd00b7
Autor:
Sheila Fernández-Luis, Maria Grazia Lain, Miquel Serna-Pascual, Sara Domínguez-Rodríguez, Louise Kuhn, Afaaf Liberty, Shaun Barnabas, Elisa Lopez-Varela, Kennedy Otwombe, Siva Danaviah, Eleni Nastouli, Paolo Palma, Nicola Cotugno, Moira Spyer, Viviana Giannuzzi, Carlo Giaquinto, Avy Violari, Mark F. Cotton, Tacilta Nhampossa, Nigel Klein, Nastassja Ramsagar, Anita Janse van Rensburg, Osee Behuhuma, Paula Vaz, Almoustapha Issiaka Maiga, Andrea Oletto, Denise Naniche, Paolo Rossi, Pablo Rojo, Alfredo Tagarro, EPIICAL Consortium
Publikováno v:
BMC Public Health, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background The World Health Organization (WHO) risk assessment algorithm for vertical transmission of HIV (VT) assumes the availability of maternal viral load (VL) result at delivery and early viral control 4 weeks after initiating antiretro
Externí odkaz:
https://doaj.org/article/cb182815e59e4d12b9fb5755fa54a7da
Autor:
Alessandra Ruggiero, Giuseppe Rubens Pascucci, Nicola Cotugno, Sara Domínguez-Rodríguez, Stefano Rinaldi, Alfredo Tagarro, Pablo Rojo, Caroline Foster, Alasdair Bamford, Anita De Rossi, Eleni Nastouli, Nigel Klein, Elena Morrocchi, Benoit Fatou, Kinga K. Smolen, Al Ozonoff, Michela Di Pastena, Katherine Luzuriaga, Hanno Steen, Carlo Giaquinto, Philip Goulder, Paolo Rossi, Ofer Levy, Savita Pahwa, Paolo Palma, the EPIICAL Consortium, Mark Cotton, Shaun Barnabas, Thanyawee Puthanakit, Louise Kuhn, Andrew Yates, Avy Violari, Kennedy Otwombe, Paula Vaz, Maria Grazia Lain, Tacilta Nampossa, Denise Naniche, Sheila Fernandez-Luis, Elisa Lopez, Holly Peay, Moira Spyer, Vincent Calvez, Anne-Genevieve Marcelin, Maria Angeles Munoz, Annalisa Dalzini, Raffaella Petrara, Kathleen Gartner, Lesley De Armas, Pahwa Rajendra, Suresh Pallikkuth, Deborah Persaud, Nicolas Chomont, Mathias Lichterfeld, Silvia Faggion, Daniel Gomez Pena, Andrea Oletto, Alessandra Nardone, Paola Zangari, Silvia Di Cesare, Chiara Medri, Olga Kolesova, Carla Paganin, William James, Inger Lindfors - Rossi, Shrabon Samiur Hassan, Francesca Mazzetto, Hellen Akisinku, Musakanya Chingandu, Francesca Rocchi, Ilaria Pepponi, Rob J. De Boer, Juliane Schroter, Viviana Giannuzzi, Sinead Morris
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundDespite a successful antiretroviral therapy (ART), adolescents living with perinatally acquired HIV (PHIV) experience signs of B-cell hyperactivation with expansion of ‘namely’ atypical B-cell phenotypes, including double negative (CD27
Externí odkaz:
https://doaj.org/article/4c3438cc6e094cf89b7fa756b480c8ba
Autor:
Sara Domínguez-Rodríguez, Miquel Serna-Pascual, Andrea Oletto, Shaun Barnabas, Peter Zuidewind, Els Dobbels, Siva Danaviah, Osee Behuhuma, Maria Grazia Lain, Paula Vaz, Sheila Fernández-Luis, Tacilta Nhampossa, Elisa Lopez-Varela, Kennedy Otwombe, Afaaf Liberty, Avy Violari, Almoustapha Issiaka Maiga, Paolo Rossi, Carlo Giaquinto, Louise Kuhn, Pablo Rojo, Alfredo Tagarro
Publikováno v:
PLoS ONE, Vol 17, Iss 10 (2022)
Logistic regression (LR) is the most common prediction model in medicine. In recent years, supervised machine learning (ML) methods have gained popularity. However, there are many concerns about ML utility for small sample sizes. In this study, we ai
Externí odkaz:
https://doaj.org/article/83369363d81944e4906a928b9436f150
Autor:
Maria Grazia Lain, Paula Vaz, Marco Sanna, Nalia Ismael, Sérgio Chicumbe, Teresa Beatriz Simione, Anna Cantarutti, Gloria Porcu, Stefano Rinaldi, Lesley de Armas, Vinh Dinh, Suresh Pallikkuth, Rajendra Pahwa, Paolo Palma, Nicola Cotugno, Savita Pahwa
Publikováno v:
Healthcare, Vol 10, Iss 11, p 2156 (2022)
Early initiation of antiretroviral therapy and adherence to achieve viral load suppression (VLS) are crucial for reducing morbidity and mortality of perinatally HIV-infected infants. In this descriptive cohort study of 39 HIV perinatally infected inf
Externí odkaz:
https://doaj.org/article/6e937d16c0e04766a23a862ed728b7fe
Autor:
Maria Grazia Lain, Sergio Chicumbe, Aleny Couto, Esmeralda Karajeanes, Carlo Giaquinto, Paula Vaz
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231143 (2020)
BACKGROUND:Determination of the human immunodeficiency virus (HIV) exposure status in infants and young children is required to guarantee timely diagnosis and access to appropriate care. HIV prevalence among Mozambican women aged 15-49 years is 15%,
Externí odkaz:
https://doaj.org/article/5e292fb5b1d64fbaa530eb627419229e
Autor:
Maria Grazia Lain, Sergio Chicumbe, Ana Rosa de Araujo, Esmeralda Karajeanes, Aleny Couto, Carlo Giaquinto, Paula Vaz
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0237993 (2020)
IntroductionComplete follow-up of human immunodeficiency virus (HIV)-exposed infants (HEI) is crucial for a successful prevention of mother-to-child HIV transmission. This study analyzed the HEI follow-up and factors associated with loss to follow-up
Externí odkaz:
https://doaj.org/article/5d6cf1c3752d410d9376dc02743dfc0a
Autor:
Catherine K, Koofhethile, Stefano, Rinaldi, Yelizaveta, Rassadkina, Vinh B, Dinh, Ce, Gao, Suresh, Pallikkuth, Pilar, Garcia-Broncano, Lesley R, de Armas, Rajendra, Pahwa, Nicola, Cotugno, Paula, Vaz, Maria Grazia, Lain, Paolo, Palma, Xu G, Yu, Roger, Shapiro, Savita, Pahwa, Mathias, Lichterfeld
Publikováno v:
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases.
Persistence of HIV-1-infected cells during antiretroviral therapy is well documented, but may be modulated by early initiation of antiretroviral therapy in infants.Here, we longitudinally analyzed the proviral landscape in 9 infants with vertical HIV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::326f6683fcc310dc2e5452f4caceddba
https://pubmed.ncbi.nlm.nih.gov/36476348
https://pubmed.ncbi.nlm.nih.gov/36476348