Association of a gene-expression subtype to outcome and treatment response in patients with recurrent/metastatic head and neck squamous cell carcinoma treated with nivolumab

Autor: Nerina Denaro, Lisa Licitra, Marco Merlano, Francesco Perri, Paolo Bossi, Cristina Gurizzan, Federica Perrone, Athanassios Argiris, Loris De Cecco, Stefano Cavalieri, Mara Serena Serafini, Federico Pistore, Deborah Lenoci, Silvana Canevari, Mario Airoldi, Maria Cossu Rocca, Primoz Strojan, Cvetka Grasic Kuhar, Andrea Vingiani, Maria Grazia Ghi, Alessandra Cassano, Giacomo Allegrini

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 12, Iss 1 (2024)

Background Immune checkpoint inhibitors have been approved and currently used in the clinical management of recurrent and metastatic head and neck squamous cell carcinoma (R/M HNSCC) patients. The reported benefit in clinical trials is variable and h

Externí odkaz: https://doaj.org/article/b9740be0719d4304a7e872232992bfd0

The efficacy of immunonutrition in improving tolerance to chemoradiotherapy in patients with head and neck cancer, receiving nutritional counseling: study protocol of a randomized, open-label, parallel group, bicentric pilot study

Autor: Riccardo Caccialanza, Emanuele Cereda, Catherine Klersy, Mariateresa Nardi, Sara Masi, Silvia Crotti, Silvia Cappello, Valentina Caissutti, Carlotta Brovia, Federica Lobascio, Elena Formisano, Sara Colombo, Andrea Riccardo Filippi, Elisabetta Bonzano, Patrizia Comoli, Laura Catenacci, Andrea Alberti, Valeria Musella, Alessandra Ferrari, Ilaria Imarisio, Richard Tancredi, Teresa Monaco, Maria Grazia Ghi, Paolo Bossi, Paolo Pedrazzoli

Publikováno v: Therapeutic Advances in Medical Oncology, Vol 13 (2021)

Background: Nutritional support, including nutritional counseling and oral nutritional supplements (ONSs), has been recommended at the earliest opportunity in head and neck (H&N) cancer patients. The limited available evidence on the efficacy of immu

Externí odkaz: https://doaj.org/article/e71d096b202649aa9543aa2076a37d09

First‐line cetuximab + platinum‐based therapy for recurrent/metastatic head and neck squamous cell carcinoma: A real‐world observational study— ENCORE

Autor: Christophe Le Tourneau, Massimo Ghiani, Maria Chiara Cau, Roberta Depenni, Graziana Ronzino, Pierluigi Bonomo, Vincenzo Montesarchio, Luigi Leo, Jeltje Schulten, Satu Salmio, Diethelm Messinger, Andrea Sbrana, Edith Borcoman, Maria Grazia Ghi

Publikováno v: Cancer Reports. 6

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f3aac4d79949cef5cbd38602287c3927
https://doi.org/10.1002/cnr2.1804

Immune-related gene expression signature in patients with recurrent/metastatic head and neck cancer treated with immunotherapy

Autor: Lisa F. Licitra, Mara Serena Serafini, Federico Pistore, Deborah Lenoci, Mario Airoldi, Maria Cossu Rocca, Primoz Strojan, Cvetka Grasic Kuhar, Marco C. Merlano, Nerina Denaro, Francesco Perri, Athanassios Argiris, Cristina Gurizzan, Federica Perrone, Maria Grazia Ghi, Alessandra Cassano, Giacomo Allegrini, Loris De Cecco, Paolo Bossi

Publikováno v: Journal of Clinical Oncology. 40:6051-6051

6051 Background: In platinum-resistant recurrent-metastatic (R/M) head and neck squamous cell carcinoma (HNSCC) patients (pts), survival improvements have been achieved with immune checkpoint inhibitors (ICI), however this benefit is limited to a rel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c9c66ee6b83fb456d5b2a709945d7b3a
https://doi.org/10.1200/jco.2022.40.16_suppl.6051

Chemotherapy and radiotherapy in locally advanced head and neck cancer: an individual patient data network meta-analysis

Autor: Brian O'Sullivan, Everett E. Vokes, J. Bernier, J. Vermorken, Jean-Jacques Mazeron, J.W. Lee, J. Simes, Carlo Fallai, P. Olmi, Cai Grau, K.H. Cho, B. Lacas, J.J. Cruz Hernandez, P. Graff-Cailleaud, Branislav Jeremic, J. Overgaard, Giuseppe Sanguineti, J.H. Hay, Voichita Bar-Ad, B. Gery, H. Quon, W. Dobrowsky, B. Maciejewski, M. Nankivell, Catherine Fortpied, Y. Belkacemi, Z. Szutkowski, V. Budach, David J. Adelstein, Maria Grazia Ghi, Allan Hackshaw, A. Trotti, Vincent Grégoire, Jens Overgaard, P. Blanchard, David I. Rosenthal, B. O'Sullivan, B.G. Haffty, Ju-Whei Lee, E. Moyal, M. Alfonsi, O. Choussy, S. Kumar, Barbara Burtness, M. Cheugoua-Zanetsie, C.M.P. Viegas, V. Tseroni, E. Lartigau, H. Bartelink, Björn Zackrisson, Jean-Pierre Pignon, S. Staar, J. Waldron, J.S. Wu, A. Lopes, M.G. Ghi, Sarbani Ghosh Laskar, Lisa Licitra, K.D Wernecke, C. Grau, Y.G. Tao, J. Agarwal, Yoann Pointreau, Maurice Cheugoua-Zanetsie, M. Lotayef, G. Calais, Claire Petit, J. Moon, J.A. Langendijk, C.A. Kristensen, W. Budach, Mahesh K.B. Parmar, Mahesh K. B. Parmar, Athanassios Argiris, Benjamin Lacas, C. Sire, S. Spencer, Beth M. Beadle, C. Petit, John Simes, Michael Poulsen, Arlene A. Forastiere, Q.T. Le, Adam S. Garden, L.P. Zhong, J.J. Mazeron, H. van Tinteren, Å. Bratland, Jean Pierre Pignon, Yi Li, Jeffrey S Tobias, S.H. Moon, P. Strojan, J. Bourhis, S. Temam, A. Bacigalupo, Pedro A. Torres-Saavedra, E.E. Vokes, C.M.L. Driessen, Stéphane Temam, M.M Dominello, E. Chamorey, J. Widder, Ricardo Hitt, C. van Herpen, Séverine Racadot, M. Julieron, H. Yamazaki, Rafał Suwiński, Z. Takácsi-Nagy, A. Hansen, K. Skladowski, D. Chaukar, P. Lee, S. Hayoz, F. Lewin, Marshall R. Posner, Atul Sharma, S. Mehta, M.G. Poulsen, S. Ghosh Laskar, R. Suwinski, B. Campbell, Wojciech Michalski, Jimmy J. Caudell, Jørgen Johansen, C. Simon, C. Fortpied, R. Orecchia, Volker Budach, George Shenouda, V. Torri, Shaleen Kumar, E Haddad, P. Rovea, P. Torres-Saavedra, Juan Jesús Cruz Hernández, Lai-Ping Zhong, Quynh-Thu Le, B. Zaktonik, J.W. Denham, A. Aupérin, B. Zackrisson, Gregory T. Wolf, J.C. Horiot, C. Stromberger, Jean Bourhis, S. Chabaud, Michel Lapeyre, Eric Lartigau, S.J. Wong, George Fountzilas, P. Nilsson, David M. Brizel, M.R. Posner, L. Tripcony, René-Jean Bensadoun, C. Jones, M.G. Ruo Redda, Pierre Blanchard, D. Thomson, A. Hackshaw, B. Jeremic, G. Sanguineti, Pirus Ghadjar, A. Auperin, P. Garaud

Publikováno v: Lancet Oncology, 22, 727-736
Petit, C, Lacas, B, Pignon, J-P, Le, Q T, Grégoire, V, Grau, C, Hackshaw, A, Zackrisson, B, Parmar, M K B, Lee, J-W, Ghi, M G, Sanguineti, G, Temam, S, Cheugoua-Zanetsie, M, O'Sullivan, B, Posner, M R, Vokes, E E, Cruz Hernandez, J J, Szutkowski, Z, Lartigau, E, Budach, V, Suwiński, R, Poulsen, M, Kumar, S, Ghosh Laskar, S, Mazeron, J-J, Jeremic, B, Simes, J, Zhong, L-P, Overgaard, J, Fortpied, C, Torres-Saavedra, P, Bourhis, J, Aupérin, A, Blanchard, P & MACH-NC and MARCH Collaborative Groups 2021, ' Chemotherapy and radiotherapy in locally advanced head and neck cancer : an individual patient data network meta-analysis ', The Lancet Oncology, vol. 22, no. 5, pp. 727-736 . https://doi.org/10.1016/S1470-2045(21)00076-0
The Lancet Oncology, 22(5), 727-736. ELSEVIER SCIENCE INC
Lancet Oncology, 22, 5, pp. 727-736
Petit, C, Lacas, B, Pignon, J P, Le, Q T, Grégoire, V, Grau, C, Hackshaw, A, Zackrisson, B, Parmar, M K B, Lee, J W, Ghi, M G, Sanguineti, G, Temam, S, Cheugoua-Zanetsie, M, O'Sullivan, B, Posner, M R, Vokes, E E, Cruz Hernandez, J J, Szutkowski, Z, Lartigau, E, Budach, V, Suwiński, R, Poulsen, M, Kumar, S, Ghosh Laskar, S, Mazeron, J J, Jeremic, B, Simes, J, Zhong, L P, Overgaard, J, Fortpied, C, Torres-Saavedra, P, Bourhis, J, Aupérin, A, Blanchard, P, MACH-NC and MARCH Collaborative Groups & Johansen, J 2021, ' Chemotherapy and radiotherapy in locally advanced head and neck cancer : an individual patient data network meta-analysis ', The Lancet Oncology, vol. 22, no. 5, pp. 727-736 . https://doi.org/10.1016/S1470-2045(21)00076-0

Contains fulltext : 235407.pdf (Publisher’s version ) (Closed access) BACKGROUND: Randomised, controlled trials and meta-analyses have shown the survival benefit of concomitant chemoradiotherapy or hyperfractionated radiotherapy in the treatment of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1259a72c5e0b5c71717fac9506bddb8
http://hdl.handle.net/2066/235407