Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Maria Grazia Diodoro"'
Autor:
Silvia Sozzi, Isabella Manni, Cristiana Ercolani, Maria Grazia Diodoro, Armando Bartolazzi, Francesco Spallotta, Giulia Piaggio, Laura Monteonofrio, Silvia Soddu, Cinzia Rinaldo, Davide Valente
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-16 (2024)
Abstract Background Pancreatic ductal adenocarcinoma (PDAC) features KRAS mutations in approximately 90% of human cases and excessive stromal response, termed desmoplastic reaction. Oncogenic KRAS drives pancreatic carcinogenesis by acting on both ep
Externí odkaz:
https://doaj.org/article/3c9be5d895a14f8e868aacd7a6796b4d
Autor:
Silvia Di Agostino, Valeria Canu, Sara Donzelli, Claudio Pulito, Andrea Sacconi, Federica Ganci, Fabio Valenti, Frauke Goeman, Stefano Scalera, Francesca Rollo, Anna Bagnato, Maria Grazia Diodoro, Enrico Vizza, Mariantonia Carosi, Beatrice Rufini, Orietta Federici, Manuel Giofrè, Fabio Carboni, Paola Muti, Gennaro Ciliberto, Sabrina Strano, Mario Valle, Giovanni Blandino
Publikováno v:
Cell Death and Disease, Vol 14, Iss 8, Pp 1-14 (2023)
Abstract Hyperthermic intraperitoneal administration of chemotherapy (HIPEC) increases local drug concentrations and reduces systemic side effects associated with prolonged adjuvant intraperitoneal exposure in patients affected by either peritoneal m
Externí odkaz:
https://doaj.org/article/a6afbed3464b41158ce459a31c85a615
Autor:
Mario Cioce, Maria Rita Fumagalli, Sara Donzelli, Frauke Goeman, Valeria Canu, Daniela Rutigliano, Giulia Orlandi, Andrea Sacconi, Claudio Pulito, Alina Catalina Palcau, Maurizio Fanciulli, Aldo Morrone, Maria Grazia Diodoro, Marco Caricato, Anna Crescenzi, Martina Verri, Vito Michele Fazio, Stefano Zapperi, Massimo Levrero, Sabrina Strano, Gian Luca Grazi, Caterina La Porta, Giovanni Blandino
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-22 (2023)
Abstract Background Approximately 20–50% of patients presenting with localized colorectal cancer progress to stage IV metastatic disease (mCRC) following initial treatment and this is a major prognostic determinant. Here, we have interrogated a het
Externí odkaz:
https://doaj.org/article/a12078091db24f6e823473565b12efbf
Autor:
Angelina Pranteda, Valentina Piastra, Martina Serra, Roberta Bernardini, Federica Lo Sardo, Silvia Carpano, Maria Grazia Diodoro, Armando Bartolazzi, Michele Milella, Giovanni Blandino, Gianluca Bossi
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 167, Iss , Pp 115480- (2023)
Colorectal cancer (CRC) patients with BRAF mutations develop resistance to BRAF inhibitors at a very early stage. Understanding the molecular mechanisms involved in BRAF inhibitor resistance is critical for the development of novel therapeutic opport
Externí odkaz:
https://doaj.org/article/9d7b8cc690a34230a359df41b031e9c8
Autor:
Frauke Goeman, Francesca De Nicola, Carla Azzurra Amoreo, Stefano Scalera, Daniele Marinelli, Francesca Sperati, Marco Mazzotta, Irene Terrenato, Matteo Pallocca, Ludovica Ciuffreda, Eleonora Sperandio, Maddalena Barba, Laura Pizzuti, Domenico Sergi, Antonella Amodio, Giancarlo Paoletti, Eriseld Krasniqi, Patrizia Vici, Beatrice Casini, Enzo Gallo, Simonetta Buglioni, Maria Grazia Diodoro, Edoardo Pescarmona, Ilio Vitale, Ruggero De Maria, Gian Luca Grazi, Gennaro Ciliberto, Maurizio Fanciulli, Marcello Maugeri‐Saccà
Publikováno v:
Clinical and Translational Medicine, Vol 10, Iss 8, Pp n/a-n/a (2020)
Externí odkaz:
https://doaj.org/article/5bdf37083f3a42148bff33e644819592
Autor:
Mariangela De Robertis, Tommaso Mazza, Caterina Fusilli, Luisa Loiacono, Maria Luana Poeta, Massimo Sanchez, Emanuela Massi, Giuseppe Lamorte, Maria Grazia Diodoro, Edoardo Pescarmona, Emanuela Signori, Graziano Pesole, Angelo Luigi Vescovi, Jesus Garcia-Foncillas, Vito Michele Fazio
Publikováno v:
Molecular Cancer, Vol 17, Iss 1, Pp 1-9 (2018)
Abstract EphB2 and EphA2 control stemness and differentiation in the intestinal mucosa, but the way they cooperate with the complex mechanisms underlying tumor heterogeneity and how they affect the therapeutic outcome in colorectal cancer (CRC) patie
Externí odkaz:
https://doaj.org/article/a4894f09e2574323b31d8cfe65188d20
Autor:
Matteo Pallocca, Frauke Goeman, Francesca De Nicola, Elisa Melucci, Francesca Sperati, Irene Terrenato, Laura Pizzuti, Beatrice Casini, Enzo Gallo, Carla Azzurra Amoreo, Patrizia Vici, Luigi Di Lauro, Simonetta Buglioni, Maria Grazia Diodoro, Edoardo Pescarmona, Marco Mazzotta, Maddalena Barba, Maurizio Fanciulli, Ruggero De Maria, Gennaro Ciliberto, Marcello Maugeri-Saccà
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-6 (2018)
Abstract We have previously reported that nuclear expression of the Hippo transducer TAZ in association with Wnt pathway mutations negatively impacts survival outcomes in advanced gastric cancer (GC) patients. Here, we extended these previous finding
Externí odkaz:
https://doaj.org/article/86f47c25616445ca9ed68f0ca5d505c4
Autor:
Elisa Melucci, Beatrice Casini, Livia Ronchetti, Laura Pizzuti, Francesca Sperati, Matteo Pallocca, Francesca De Nicola, Frauke Goeman, Enzo Gallo, Carla Azzurra Amoreo, Domenico Sergi, Irene Terrenato, Patrizia Vici, Luigi Di Lauro, Maria Grazia Diodoro, Edoardo Pescarmona, Maddalena Barba, Marco Mazzotta, Marcella Mottolese, Maurizio Fanciulli, Gennaro Ciliberto, Ruggero De Maria, Simonetta Buglioni, Marcello Maugeri-Saccà
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-11 (2018)
Abstract Background An extensive crosstalk co-regulates the Hippo and Wnt pathway. Preclinical studies revealed that the Hippo transducers YAP/TAZ mediate a number of oncogenic functions in gastric cancer (GC). Moreover, comprehensive characterizatio
Externí odkaz:
https://doaj.org/article/6448787b343f441c9af4da0f5800ea04
Autor:
Alessandra Viel, Alessandro Bruselles, Ettore Meccia, Mara Fornasarig, Michele Quaia, Vincenzo Canzonieri, Eleonora Policicchio, Emanuele Damiano Urso, Marco Agostini, Maurizio Genuardi, Emanuela Lucci-Cordisco, Tiziana Venesio, Aline Martayan, Maria Grazia Diodoro, Lupe Sanchez-Mete, Vittoria Stigliano, Filomena Mazzei, Francesca Grasso, Alessandro Giuliani, Marta Baiocchi, Roberta Maestro, Giuseppe Giannini, Marco Tartaglia, Ludmil B. Alexandrov, Margherita Bignami
Publikováno v:
EBioMedicine, Vol 20, Iss C, Pp 39-49 (2017)
8-Oxoguanine, a common mutagenic DNA lesion, generates G:C>T:A transversions via mispairing with adenine during DNA replication. When operating normally, the MUTYH DNA glycosylase prevents 8-oxoguanine-related mutagenesis by excising the incorporated
Externí odkaz:
https://doaj.org/article/87411eb9092b40f79ab724c1640e5e09
Autor:
Veronica Gatti, Manuela Ferrara, Ilaria Virdia, Silvia Matteoni, Laura Monteonofrio, Simona di Martino, Maria Grazia Diodoro, Giuliana Di Rocco, Cinzia Rinaldo, Silvia Soddu
Publikováno v:
Cells, Vol 9, Iss 2, p 484 (2020)
HIPK2 is a DYRK-like kinase involved in cellular stress response pathways, development, and cell division. Two alternative splice variants of HIPK2, HIPK2-FL and HIPK2-Δe8, have been previously identified as having different protein stability but si
Externí odkaz:
https://doaj.org/article/b5fcd4f05f56494e9196691901c69c94