Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Maria Grazia Del Giudice"'
Autor:
Mauro Rassu, Maria Grazia Del Giudice, Simona Sanna, Jean Marc Taymans, Michele Morari, Alberto Brugnoli, Martina Frassineti, Alessandra Masala, Sonia Esposito, Manuela Galioto, Cristiana Valle, Maria Teresa Carri, Alice Biosa, Elisa Greggio, Claudia Crosio, Ciro Iaccarino
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0179082 (2017)
Mutations in LRRK2 play a critical role in both familial and sporadic Parkinson's disease (PD). Up to date, the role of LRRK2 in PD onset and progression remains largely unknown. However, experimental evidence highlights a critical role of LRRK2 in t
Externí odkaz:
https://doaj.org/article/0a7431806839439092778c00ee0bc4a3
Autor:
Rossana Migheli, Maria Grazia Del Giudice, Ylenia Spissu, Giovanna Sanna, Yulan Xiong, Ted M Dawson, Valina L Dawson, Manuela Galioto, Gaia Rocchitta, Alice Biosa, Pier Andrea Serra, Maria Teresa Carri, Claudia Crosio, Ciro Iaccarino
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77198 (2013)
The leucine-rich repeat kinase 2 (LRRK2) gene was found to play a role in the pathogenesis of both familial and sporadic Parkinson's disease (PD). LRRK2 encodes a large multi-domain protein that is expressed in different tissues. To date, the physiol
Externí odkaz:
https://doaj.org/article/656bc98dac474b0180d333ec207576ee
Autor:
Martina Frassineti, Sonia Esposito, Ciro Iaccarino, Mauro Rassu, Jean-Marc Taymans, Alessandra Masala, Cristiana Valle, Alice Biosa, Maria Teresa Carrì, Manuela Galioto, Alberto Brugnoli, Claudia Crosio, Michele Morari, Maria Grazia Del Giudice, Simona Sanna, Elisa Greggio
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0179082 (2017)
PLoS ONE
PLoS ONE
Mutations in LRRK2 play a critical role in both familial and sporadic Parkinson’s disease (PD). Up to date, the role of LRRK2 in PD onset and progression remains largely unknown. However, experimental evidence highlights a critical role of LRRK2 in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65433fcb4033d074105a37e7c1bde31c
http://eprints.uniss.it/11797/
http://eprints.uniss.it/11797/
Publikováno v:
Biochemical Society Transactions. 40:1117-1122
Mutations in LRRK2 (leucine-rich repeat kinase 2) (also known as PARK8 or dardarin) are responsible for the autosomal-dominant form of PD (Parkinson's disease). LRRK2 mutations were found in approximately 3–5% of familial and 1–3% of sporadic PD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e533e0217fdb29b9b645a016b35b616
https://doi.org/10.1042/bst20120117
https://doi.org/10.1042/bst20120117
Autor:
Elisa Greggio, Ciro Iaccarino, Mark R. Cookson, Rita Derua, Yan Li, Elisa Belluzzi, Etienne Waelkens, Maria Grazia Del Giudice, Giorgio Arrigoni, Laura Civiero, Lauran Reyniers, Jean-Marc Taymans, Veerle Baekelandt, Evy Lobbestael, Claudia Crosio, Alexandra Beilina
Genetic studies show that LRRK2, and not its closest paralogue LRRK1, is linked to Parkinson's disease. To gain insight into the molecular and cellular basis of this discrepancy, we searched for LRRK1- and LRRK2-specific cellular processes by identif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3f88616a825ebc6db663190af96b0d7
http://hdl.handle.net/11577/2890100
http://hdl.handle.net/11577/2890100
Autor:
Valina L. Dawson, Maria Grazia Del Giudice, Manuela Galioto, Alice Biosa, Maria Teresa Carrì, Rossana Migheli, Ciro Iaccarino, Ylenia Spissu, Claudia Crosio, Pier Andrea Serra, Gaia Giovanna Maria Rocchitta, Ted M. Dawson, Yulan Xiong, Giovanna Sanna
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 10, p e77198 (2013)
PLoS ONE, Vol 8, Iss 10, p e77198 (2013)
The leucine-rich repeat kinase 2 (LRRK2) gene was found to play a role in the pathogenesis of both familial and sporadic Parkinson’s disease (PD). LRRK2 encodes a large multi-domain protein that is expressed in different tissues. To date, the physi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::329d33bbde5b4a0ee12979a28329dc13
http://hdl.handle.net/2108/85389
http://hdl.handle.net/2108/85389