Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Maria Grazia Atzori"'
Autor:
Federica Ruffini, Claudia Ceci, Maria Grazia Atzori, Simona Caporali, Lauretta Levati, Laura Bonmassar, Gian Carlo Antonini Cappellini, Stefania D’Atri, Grazia Graziani, Pedro Miguel Lacal
Publikováno v:
Pharmacological Research, Vol 192, Iss , Pp 106782- (2023)
Melanoma resistance to BRAF inhibitors (BRAFi) is often accompanied by a switch from a proliferative to an invasive phenotype. Therefore, the identification of signaling molecules involved in the development of metastatic properties by resistant mela
Externí odkaz:
https://doaj.org/article/8a4322fd7f85473abdc2bd80fa190bb0
Autor:
Diego Sbardella, Grazia Raffaella Tundo, Alice Mecchia, Camilla Palumbo, Maria Grazia Atzori, Lauretta Levati, Alessandra Boccaccini, Anna Maria Caccuri, Paolo Cascio, Pedro Miguel Lacal, Grazia Graziani, Monica Varano, Massimiliano Coletta, Mariacristina Parravano
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-21 (2022)
Key Points High glucose quickly induces an atypical NF-kB pro-inflammatory program. CamKII phosphorylation of Rpt6 subunit of the proteasome stimulates IkBα turnover and p65-p50 release. Inhibition of either CamkII or proteasome blocks this pathway.
Externí odkaz:
https://doaj.org/article/2be4c18062b14db4b2e146a57820f67c
Autor:
Grazia Raffaella Tundo, Diego Sbardella, Francesco Oddone, Giuseppe Grasso, Stefano Marini, Maria Grazia Atzori, Anna Maria Santoro, Danilo Milardi, Francesco Bellia, Gabriele Macari, Grazia Graziani, Fabio Polticelli, Paolo Cascio, Mariacristina Parravano, Massimo Coletta
Publikováno v:
Biomolecules, Vol 12, Iss 2, p 315 (2022)
Carfilzomib is a last generation proteasome inhibitor (PI) with proven clinical efficacy in the treatment of relapsed/refractory multiple myeloma. This drug is considered to be extremely specific in inhibiting the chymotrypsin-like activity of the 20
Externí odkaz:
https://doaj.org/article/649f3bdc524743eb87fddf5a6256af99
Autor:
Maria Grazia Atzori, Lucio Tentori, Federica Ruffini, Claudia Ceci, Lucia Lisi, Elena Bonanno, Manuel Scimeca, Eskil Eskilsson, Thomas Daubon, Hrvoje Miletic, Lucia Ricci Vitiani, Roberto Pallini, Pierluigi Navarra, Rolf Bjerkvig, Stefania D’Atri, Pedro Miguel Lacal, Grazia Graziani
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 36, Iss 1, Pp 1-15 (2017)
Abstract Background Glioblastoma (GBM) is a highly migratory, invasive, and angiogenic brain tumor. Like vascular endothelial growth factor-A (VEGF-A), placental growth factor (PlGF) promotes GBM angiogenesis. VEGF-A is a ligand for both VEGF recepto
Externí odkaz:
https://doaj.org/article/21f609d6b22d4a21bee8c1e043aab86e
Autor:
Maria Grazia Atzori, Claudia Ceci, Federica Ruffini, Manuel Scimeca, Rosella Cicconi, Maurizio Mattei, Pedro Miguel Lacal, Grazia Graziani
Publikováno v:
Cancers; Volume 14; Issue 22; Pages: 5578
Placenta growth factor (PlGF) is a member of the vascular endothelial growth factor (VEGF) family involved in tumor-associated angiogenesis and melanoma invasion of the extra-cellular matrix (ECM) through activation of membrane VEGF receptor 1 (VEGFR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aedefb0e4e89a07f17fba063b67a7a6a
Autor:
Diego Ph.D. Diego Sba, Grazia Raffaella Tundo, Alice Mecchia, Camilla Palumbo, Maria Grazia Atzori, Lauretta Levati, Anna Maria Caccuri, Paolo Cascio, Pedro Lacal, Grazia Graziani, Monica Varano, Massimiliano Coletta, Maria Cristina Parravano
BackgroundDiabetic retinopathy (DR) is a microvascular complication of diabetes with a heavy impact on the life-quality of subjects and with a dramatic burden for health and economic systems on a global scale.Although the pathogenesis of DR is largel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68afcf3a6d9e319645db12b174dd5c16
https://doi.org/10.21203/rs.3.rs-1116573/v1
https://doi.org/10.21203/rs.3.rs-1116573/v1
Autor:
Diego Sbardella, Grazia Raffaella Tundo, Alice Mecchia, Camilla Palumbo, Maria Grazia Atzori, Lauretta Levati, Alessandra Boccaccini, Anna Maria Caccuri, Paolo Cascio, Pedro Miguel Lacal, Grazia Graziani, Monica Varano, Massimiliano Coletta, Mariacristina Parravano
Publikováno v:
Cellbioscience. 12(1)
Background Diabetic retinopathy (DR) is a microvascular complication of diabetes with a heavy impact on the quality of life of subjects and with a dramatic burden for health and economic systems on a global scale. Although the pathogenesis of DR is l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aae1cd42771460c1617087f4b425f2c3
https://pubmed.ncbi.nlm.nih.gov/35842713
https://pubmed.ncbi.nlm.nih.gov/35842713
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 4, p 1388 (2020)
International Journal of Molecular Sciences, Vol 21, Iss 4, p 1388 (2020)
The vascular endothelial growth factor (VEGF) family members, VEGF-A, placenta growth factor (PlGF), and to a lesser extent VEGF-B, play an essential role in tumor-associated angiogenesis, tissue infiltration, and metastasis formation. Although VEGF-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63310fde50d26aa858b136956cf00821
https://pubmed.ncbi.nlm.nih.gov/32085654
https://pubmed.ncbi.nlm.nih.gov/32085654
Autor:
Rosella Cicconi, Grazia Graziani, Manuel Scimeca, Roberta Bernardini, Pedro Miguel Lacal, Lucio Tentori, Elena Bonanno, Maria Grazia Atzori, Federica Ruffini, Stefania D'Atri, Maurizio Mattei
The vascular endothelial growth factor receptor-1 (VEGFR-1) is a membrane receptor for VEGF-A, placenta growth factor (PlGF) and VEGF-B that plays a crucial role in melanoma invasiveness, vasculogenic mimicry and tumor-associated angiogenesis. Furthe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4655779bd12726d979a3f7c3d816ee3b
http://hdl.handle.net/2108/256590
http://hdl.handle.net/2108/256590
Autor:
Claudia Ceci, Maria Luisa Barbaccia, Pedro Miguel Lacal, Maria Grazia Atzori, Stefania D'Atri, Mauro Trapani, Grazia Graziani, Lucio Tentori, Federica Ruffini
Publikováno v:
Journal of Cellular and Molecular Medicine
The vascular endothelial growth factor receptor‐1 (VEGFR‐1) is a tyrosine kinase receptor frequently expressed in melanoma. Its activation by VEGF‐A or placental growth factor (PlGF) promotes tumour cell survival, migration and invasiveness. Mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78649ca9a820f706b95e9d946e535ca5
https://pubmed.ncbi.nlm.nih.gov/31758648
https://pubmed.ncbi.nlm.nih.gov/31758648