Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Maria Giulia Varrica"'
Autor:
Antonio Rescifina, Giulia Monciino, Placido Mineo, Chiara Zagni, Venerando Pistarà, Emanuele Amata, Angelo Nicosia, Giuseppe Floresta, Maria Giulia Varrica, Antonio Abbadessa, Rogerio M. Castilho
Publikováno v:
European Journal of Medicinal Chemistry. 143:583-590
((3RS,5SR)- and ((3RS,5RS)-2-(2-methoxybenzyl)-3-(1,10-phenanthrolin-2-yl)isoxazolidin-5-yl)methanol have been synthesized, according to 1,3-dipolar cycloaddition methodology, as DNA intercalating agents and evaluated for their anticancer activity ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d15bc11e93728e5d4df2e5c133a3015a
https://doi.org/10.1016/j.ejmech.2017.11.067
https://doi.org/10.1016/j.ejmech.2017.11.067
Publikováno v:
European Journal of Medicinal Chemistry. 74:95-115
The interaction of small molecules with DNA plays an essential role in many biological processes. As DNA is often the target for majority of anticancer and antibiotic drugs, study about the interaction of drug and DNA has a key role in pharmacology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07f20a37b1799097e8cd75ea008bf3b2
https://doi.org/10.1016/j.ejmech.2013.11.029
https://doi.org/10.1016/j.ejmech.2013.11.029
Publikováno v:
ChemInform. 45
The interaction of small molecules with DNA plays an essential role in many biological processes. As DNA is often the target for majority of anticancer and antibiotic drugs, study about the interaction of drug and DNA has a key role in pharmacology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e84ceedfa013924bbff27fc318f19c1e
https://doi.org/10.1002/chin.201419287
https://doi.org/10.1002/chin.201419287
Publikováno v:
ChemInform. 43
The third generation of isoxazole polycyclic aromatic hydrocarbons, possessing binding constants enabling easy diffusion of targeting remotely implanted tumors, is synthesized accordingly to the 1,3-dipolar cycloaddition methodology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8cd36bc94493152a9bead30e7a1b7985
https://doi.org/10.1002/chin.201239142
https://doi.org/10.1002/chin.201239142