Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Maria Gessica Ciulla"'
Autor:
Ariel Ramirez-Labrada, Llipsy Santiago, Cecilia Pesini, Marta Arrieta, Maykel Arias, Adanays Calvo Pérez, Maria Gessica Ciulla, Mahdi Forouharshad, Julian Pardo, Eva M. Gálvez, Fabrizio Gelain
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract Self-assembling peptides (SAPs) have gained significant attention in biomedicine because of their unique properties and ability to undergo molecular self-assembly driven by non-covalent interactions. By manipulating their composition and str
Externí odkaz:
https://doaj.org/article/b8528ca61b42443f8f7057c038b3b3b6
Autor:
Maria Gessica Ciulla, Fabrizio Gelain
Publikováno v:
Microbial Biotechnology, Vol 16, Iss 4, Pp 757-777 (2023)
Abstract Antimicrobial peptides play a crucial role in innate immunity, whose components are mainly peptide‐based molecules with antibacterial properties. Indeed, the exploration of the immune system over the past 40 years has revealed a number of
Externí odkaz:
https://doaj.org/article/ec23ec10a64b414f8bc51db61fbe7356
Autor:
Amanda Marchini, Maria Gessica Ciulla, Barbara Antonioli, Alessandro Agnoli, Umberto Bovio, Virginia Visnoviz, Federico Bertuzzi, Fabrizio Gelain
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Human pancreatic islets transplantation is an experimental therapeutic treatment for Type I Diabetes. Limited islets lifespan in culture remains the main drawback, due to the absence of native extracellular matrix as mechanical support after their en
Externí odkaz:
https://doaj.org/article/7f249e73891845fc8d385242144d2a7b
Autor:
Mahdi Forouharshad, Andrea Raspa, Amanda Marchini, Maria Gessica Ciulla, Alice Magnoni, Fabrizio Gelain
Publikováno v:
Pharmaceutics, Vol 15, Iss 9, p 2261 (2023)
Spinal cord regeneration using stem cell transplantation is a promising strategy for regenerative therapy. Stem cells transplanted onto scaffolds that can mimic natural extracellular matrix (ECM) have the potential to significantly improve outcomes.
Externí odkaz:
https://doaj.org/article/074833c0fcaf40fb8f019ceaa68da56a
Publikováno v:
Nanomaterials, Vol 12, Iss 3, p 320 (2022)
Tissue engineering (TE) strategies require the design and characterization of novel biomaterials capable of mimicking the physiological microenvironments of the tissues to be regenerated. As such, implantable materials should be biomimetic, nanostruc
Externí odkaz:
https://doaj.org/article/25f86039ec4e4062b05d5683fba78a82
Publikováno v:
Pharmaceuticals, Vol 13, Iss 8, p 198 (2020)
A practical and robust synthetic method to obtain the natural disaccharide sambubiose (2-O-β-D-xylopyranosyl-D-glucopyranose) is reported, exploring the key step in the synthesis, i.e., stereoselective O-glycosylation. Specifically, the best combina
Externí odkaz:
https://doaj.org/article/7fddac50b38a4f0eb06ceb72317cc84b
Autor:
Caitlin Davies, Lara Dötsch, Maria Gessica Ciulla, Elisabeth Hennes, Kei Yoshida, Raphael Gasper, Rebecca Scheel, Sonja Sievers, Carsten Strohmann, Kamal Kumar, Slava Ziegler, Herbert Waldmann
Publikováno v:
Angewandte Chemie (International ed. in English). 61(40)
Natural product (NP)-inspired design principles provide invaluable guidance for bioactive compound discovery. Pseudo-natural products (PNPs) are de novo combinations of NP fragments to target biologically relevant chemical space not covered by NPs. W
Publikováno v:
Nanomaterials, Vol 12, Iss 320, p 320 (2022)
Nanomaterials; Volume 12; Issue 3; Pages: 320
Nanomaterials; Volume 12; Issue 3; Pages: 320
Tissue engineering (TE) strategies require the design and characterization of novel biomaterials capable of mimicking the physiological microenvironments of the tissues to be regenerated. As such, implantable materials should be biomimetic, nanostruc
Autor:
Maria Gessica Ciulla, Kamal Kumar
Publikováno v:
Tetrahedron Letters. 59:3223-3233
The emergence of drug resistant bacterial infections leading to high mortality rates has posed a formidable challenge to organic synthesis and medicinal chemists to deliver potent and novel antibacterial drug candidates. In particular, antibacterial
Publikováno v:
Organicbiomolecular chemistry. 17(3)
Indole polycycles are common structural frameworks of biologically intriguing small molecules of natural and synthetic origin and therefore remain interesting and challenging synthetic targets. Cascade reactions wherein a number of reactions occur in