Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Maria Garcia-Alai"'
Autor:
Janine-Denise Kopicki, Ankur Saikia, Stephan Niebling, Christian Günther, Raghavendra Anjanappa, Maria Garcia-Alai, Sebastian Springer, Charlotte Uetrecht
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-11 (2022)
The authors present a sensitive and rapid method to determine the binding strength of MHC class 1 peptide complexes using native mass spectrometry.
Externí odkaz:
https://doaj.org/article/ce7fe7856504421aaaf381a0e810a653
Autor:
Ario de Marco, Nick Berrow, Mario Lebendiker, Maria Garcia-Alai, Stefan H. Knauer, Blanca Lopez-Mendez, André Matagne, Annabel Parret, Kim Remans, Stephan Uebel, Bertrand Raynal
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-4 (2021)
Proteins and peptides are amongst the most widely used research reagents but often their quality is inadequate and can result in poor data reproducibility. Here we propose a simple set of guidelines that, when correctly applied to protein reagents sh
Externí odkaz:
https://doaj.org/article/51ce73ae195442a99d981f1a7543b04b
Autor:
Raghavendra Anjanappa, Maria Garcia-Alai, Janine-Denise Kopicki, Julia Lockhauserbäumer, Mohamed Aboelmagd, Janina Hinrichs, Ioana Maria Nemtanu, Charlotte Uetrecht, Martin Zacharias, Sebastian Springer, Rob Meijers
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Major Histocompatibility Complex (MHC) class I molecules present tightly binding peptides on the cell surface for recognition by cytotoxic T cells. Here, the authors present the crystal structures of a disulfide-stabilized human MHC class I molecule
Externí odkaz:
https://doaj.org/article/0a9d6a6f48e3448e84d9257ff4977dbc
Autor:
Bertrand Raynal, Maria Garcia-Alai, Kim Remans, Stefan H. Knauer, Stephan Uebel, Ario de Marco, Mario Lebendiker, Annabel H. A. Parret, André Matagne, Blanca López-Méndez, Nick Berrow
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-4 (2021)
de Marco, A, Berrow, N, Lebendiker, M, Garcia-Alai, M, Knauer, S H, Lopez-Mendez, B, Matagne, A, Parret, A, Remans, K, Uebel, S & Raynal, B 2021, ' Quality control of protein reagents for the improvement of research data reproducibility ', Nature Communications, vol. 12, no. 1, 2795 . https://doi.org/10.1038/s41467-021-23167-z
Nature Communications
Nature Communications, 2021, 12 (1), pp.2795. ⟨10.1038/s41467-021-23167-z⟩
de Marco, A, Berrow, N, Lebendiker, M, Garcia-Alai, M, Knauer, S H, Lopez-Mendez, B, Matagne, A, Parret, A, Remans, K, Uebel, S & Raynal, B 2021, ' Quality control of protein reagents for the improvement of research data reproducibility ', Nature Communications, vol. 12, no. 1, 2795 . https://doi.org/10.1038/s41467-021-23167-z
Nature Communications
Nature Communications, 2021, 12 (1), pp.2795. ⟨10.1038/s41467-021-23167-z⟩
Proteins and peptides are amongst the most widely used research reagents but often their quality is inadequate and can result in poor data reproducibility. Here we propose a simple set of guidelines that, when correctly applied to protein reagents sh
Autor:
Cindy Dirscherl, Sara Löchte, Zeynep Hein, Janine-Denise Kopicki, Antonia Regina Harders, Noemi Linden, Andreas Karner, Johannes Preiner, Julian Weghuber, Maria Garcia-Alai, Charlotte Uetrecht, Martin Zacharias, Jacob Piehler, Peter Lanzerstorfer, Sebastian Springer
Publikováno v:
Journal of cell science 135(9), jcs259489 (2022). doi:10.1242/jcs.259498
Journal of cell science 135(9), jcs259489 (2022). doi:10.1242/jcs.259498
At the plasma membrane of mammalian cells, major histocompatibility complex class I molecules (MHC-I) present antigenic peptides to cytotoxic T cells. Following the loss of
At the plasma membrane of mammalian cells, major histocompatibility complex class I molecules (MHC-I) present antigenic peptides to cytotoxic T cells. Following the loss of
Autor:
Caroline Mas, Grzegorz Piszczek, Marjetka Podobnik, Kathryn Perez, Timothy Sharpe, Stephen H. McLaughlin, Roland Montserret, Stefan H. Knauer, Bruno Baron, Christopher M. Johnson, Quyen Nguyen, Mark A. Williams, Katja Pirc, Arthur Sedivy, Celeste Abreu, Tina Daviter, David Ortega-Alarcon, Daumantas Matulis, Rouba Nasreddine, Carlo Carolis, Thomas A. Jowitt, Stephan Uebel, David Staunton, Andrew P. Leech, Maria Garcia-Alai, June Southall, Alexander Fish, Jitka Holková, Alexander K. Buell, Michael Weyand, Jasmina Rokov-Plavec, Blanca López-Méndez, Sylvie Berger, Josef Houser, Natalia Rodrigo, Wojciech Bal, Chad A. Brautigam, Josef Hamacek, Reine Nehmé, Olga Abian, Christian Guenther, Ondrej Vanek, Susanne Schaefer, Sharon M. Kelly, Malgorzata Adamczyk, Di Wu, Pedro Tavares
Publikováno v:
European Biophysics Journal
European Biophysics Journal, Springer Verlag (Germany), 2021, 50 (3-4), pp.411-427. ⟨10.1007/s00249-021-01532-6⟩
European biophysics journal, New York : Springer, 2021, vol. 50, iss. 3-4, p. 411-427
European Biophysics Journal, 2021, 50 (3-4), pp.411-427. ⟨10.1007/s00249-021-01532-6⟩
López-Méndez, B, Baron, B, Brautigam, C A, Jowitt, T A, Knauer, S H, Uebel, S, Williams, M A, Sedivy, A, Abian, O, Abreu, C, Adamczyk, M, Bal, W, Berger, S, Buell, A K, Carolis, C, Daviter, T, Fish, A, Garcia-Alai, M, Guenther, C, Hamacek, J, Holková, J, Houser, J, Johnson, C, Kelly, S, Leech, A, Mas, C, Matulis, D, McLaughlin, S H, Montserret, R, Nasreddine, R, Nehmé, R, Nguyen, Q, Ortega-Alarcón, D, Perez, K, Pirc, K, Piszczek, G, Podobnik, M, Rodrigo, N, Rokov-Plavec, J, Schaefer, S, Sharpe, T, Southall, J, Staunton, D, Tavares, P, Vanek, O, Weyand, M & Wu, D 2021, ' Reproducibility and accuracy of microscale thermophoresis in the NanoTemper Monolith : a multi laboratory benchmark study ', European Biophysics Journal, vol. 50, pp. 411-427 . https://doi.org/10.1007/s00249-021-01532-6
López-Méndez, B, Baron, B, Brautigam, C A, Jowitt, T A, Knauer, S H, Uebel, S, Williams, M A, Sedivy, A, Abian, O, Abreu, C, Adamczyk, M, Bal, W, Berger, S, Büll, A K, Carolis, C, Daviter, T, Fish, A, Garcia-Alai, M, Guenther, C, Hamacek, J, Holková, J, Houser, J, Johnson, C, Kelly, S, Leech, A, Mas, C, Matulis, D, McLaughlin, S H, Montserret, R, Nasreddine, R, Nehmé, R, Nguyen, Q, Ortega-Alarcón, D, Perez, K, Pirc, K, Piszczek, G, Podobnik, M, Rodrigo, N, Rokov-Plavec, J, Schaefer, S, Sharpe, T, Southall, J, Staunton, D, Tavares, P, Vanek, O, Weyand, M & Wu, D 2021, ' Reproducibility and accuracy of microscale thermophoresis in the NanoTemper Monolith: a multi laboratory benchmark study ', European Biophysics Journal, vol. 50, pp. 411-417 . https://doi.org/10.1007/s00249-021-01532-6
European Biophysics Journal, Springer Verlag (Germany), 2021, 50 (3-4), pp.411-427. ⟨10.1007/s00249-021-01532-6⟩
European biophysics journal, New York : Springer, 2021, vol. 50, iss. 3-4, p. 411-427
European Biophysics Journal, 2021, 50 (3-4), pp.411-427. ⟨10.1007/s00249-021-01532-6⟩
López-Méndez, B, Baron, B, Brautigam, C A, Jowitt, T A, Knauer, S H, Uebel, S, Williams, M A, Sedivy, A, Abian, O, Abreu, C, Adamczyk, M, Bal, W, Berger, S, Buell, A K, Carolis, C, Daviter, T, Fish, A, Garcia-Alai, M, Guenther, C, Hamacek, J, Holková, J, Houser, J, Johnson, C, Kelly, S, Leech, A, Mas, C, Matulis, D, McLaughlin, S H, Montserret, R, Nasreddine, R, Nehmé, R, Nguyen, Q, Ortega-Alarcón, D, Perez, K, Pirc, K, Piszczek, G, Podobnik, M, Rodrigo, N, Rokov-Plavec, J, Schaefer, S, Sharpe, T, Southall, J, Staunton, D, Tavares, P, Vanek, O, Weyand, M & Wu, D 2021, ' Reproducibility and accuracy of microscale thermophoresis in the NanoTemper Monolith : a multi laboratory benchmark study ', European Biophysics Journal, vol. 50, pp. 411-427 . https://doi.org/10.1007/s00249-021-01532-6
López-Méndez, B, Baron, B, Brautigam, C A, Jowitt, T A, Knauer, S H, Uebel, S, Williams, M A, Sedivy, A, Abian, O, Abreu, C, Adamczyk, M, Bal, W, Berger, S, Büll, A K, Carolis, C, Daviter, T, Fish, A, Garcia-Alai, M, Guenther, C, Hamacek, J, Holková, J, Houser, J, Johnson, C, Kelly, S, Leech, A, Mas, C, Matulis, D, McLaughlin, S H, Montserret, R, Nasreddine, R, Nehmé, R, Nguyen, Q, Ortega-Alarcón, D, Perez, K, Pirc, K, Piszczek, G, Podobnik, M, Rodrigo, N, Rokov-Plavec, J, Schaefer, S, Sharpe, T, Southall, J, Staunton, D, Tavares, P, Vanek, O, Weyand, M & Wu, D 2021, ' Reproducibility and accuracy of microscale thermophoresis in the NanoTemper Monolith: a multi laboratory benchmark study ', European Biophysics Journal, vol. 50, pp. 411-417 . https://doi.org/10.1007/s00249-021-01532-6
Microscale thermophoresis (MST), and the closely related Temperature Related Intensity Change (TRIC), are synonyms for a recently developed measurement technique in the field of biophysics to quantify biomolecular interactions, using the (capillary-b
Autor:
Herve Celia, Vadim Kotov, Oliver Vesper, Maria Garcia-Alai, Stephan Nussberger, Susan K. Buchanan, G. Mlynek, Jiri Wald, C. Loew, Celso M. Teixeira-Duarte, Marina Pletzer, João H. Morais-Cabral, Thomas C. Marlovits, Kristina Djinović-Carugo
Publikováno v:
Protein science 30(1), 201-217 (2021). doi:10.1002/pro.3986
Protein Science : A Publication of the Protein Society
Protein Science : A Publication of the Protein Society
Protein science 30(1), 201 - 217 (2021). doi:10.1002/pro.3986
Protein stability is a key factor in successful structural and biochemical research. However, the approaches for systematic comparison of protein stability are limited by sample consu
Protein stability is a key factor in successful structural and biochemical research. However, the approaches for systematic comparison of protein stability are limited by sample consu
Autor:
Julia Lockhauserbäumer, Maria Garcia-Alai, Ioana Maria Nemtanu, Janine-Denise Kopicki, Mohamed Aboelmagd, Raghavendra Anjanappa, Sebastian Springer, Charlotte Uetrecht, Janina Hinrichs, Martin Zacharias, Rob Meijers
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nature Communications 11(1), 1314 (1-11) (2020). doi:10.1038/s41467-020-14862-4
Nature Communications
Nature Communications 11(1), 1314 (1-11) (2020). doi:10.1038/s41467-020-14862-4
Nature Communications
Major Histocompatibility Complex (MHC) class I molecules selectively bind peptides for presentation to cytotoxic T cells. The peptide-free state of these molecules is not well understood. Here, we characterize a disulfide-stabilized version of the hu
Autor:
Vasundara Srinivasan, Hévila Brognaro, Prince R. Prabhu, Edmarcia Elisa de Souza, Sebastian Günther, Patrick Y. A. Reinke, Thomas J. Lane, Helen Ginn, Huijong Han, Wiebke Ewert, Janina Sprenger, Faisal H. M. Koua, Sven Falke, Nadine Werner, Hina Andaleeb, Najeeb Ullah, Bruno Alves Franca, Mengying Wang, Angélica Luana C. Barra, Markus Perbandt, Martin Schwinzer, Christina Schmidt, Lea Brings, Kristina Lorenzen, Robin Schubert, Rafael Rahal Guaragna Machado, Erika Donizette Candido, Danielle Bruna Leal Oliveira, Edison Luiz Durigon, Stephan Niebling, Angelica Struve Garcia, Oleksandr Yefanov, Julia Lieske, Luca Gelisio, Martin Domaracky, Philipp Middendorf, Michael Groessler, Fabian Trost, Marina Galchenkova, Aida Rahmani Mashhour, Sofiane Saouane, Johanna Hakanpää, Markus Wolf, Maria Garcia Alai, Dusan Turk, Arwen R. Pearson, Henry N. Chapman, Winfried Hinrichs, Carsten Wrenger, Alke Meents, Christian Betzel
Publikováno v:
Communications biology 5(1), 805 (2022). doi:10.1038/s42003-022-03737-7
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Communications biology 5(1), 805 (2022). doi:10.1038/s42003-022-03737-7
SARS-CoV-2 papain-like protease (PLpro) covers multiple functions. Beside the cysteine-protease activity, facilitating cleavage of the viral polypeptide chain, PLpro has the
SARS-CoV-2 papain-like protease (PLpro) covers multiple functions. Beside the cysteine-protease activity, facilitating cleavage of the viral polypeptide chain, PLpro has the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::affdd7dce161e01a8421dd52dab5551f
Autor:
Fatemeh Hassani Nia, Daniel Woike, Isabel Bento, Stephan Niebling, Debora Tibbe, Kristina Schulz, Daniela Hirnet, Matilda Skiba, Hans-Hinrich Hönck, Katharina Veith, Christian Günther, Tasja Scholz, Tatjana Bierhals, Joenna Driemeyer, Renee Bend, Antonio Virgilio Failla, Christian Lohr, Maria Garcia Alai, Hans-Jürgen Kreienkamp
Publikováno v:
Molecular Psychiatry
Molecular psychiatry xx, xx (2022). doi:10.1038/s41380-022-01882-3
Molecular psychiatry xx, xx (2022). doi:10.1038/s41380-022-01882-3
Molecular psychiatry xx, xx (2022). doi:10.1038/s41380-022-01882-3
Postsynaptic scaffold proteins such as Shank, PSD-95, Homer and SAPAP/GKAP family members establish the postsynaptic density of glutamatergic synapses through a dense network of
Postsynaptic scaffold proteins such as Shank, PSD-95, Homer and SAPAP/GKAP family members establish the postsynaptic density of glutamatergic synapses through a dense network of