Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Maria García-Alai"'
Autor:
Robert Bücker, Carolin Seuring, Cornelia Cazey, Katharina Veith, Maria García-Alai, Kay Grünewald, Meytal Landau
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
In this work the authors provide high-resolution structural support for the amyloid-antimicrobial link via functional amyloids displaying propeller-like and kinked cross-β fibrils.
Externí odkaz:
https://doaj.org/article/09b5dc12870a480fbe761c3014c1047e
Autor:
Janine-Denise Kopicki, Ankur Saikia, Stephan Niebling, Christian Günther, Raghavendra Anjanappa, Maria Garcia-Alai, Sebastian Springer, Charlotte Uetrecht
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-11 (2022)
The authors present a sensitive and rapid method to determine the binding strength of MHC class 1 peptide complexes using native mass spectrometry.
Externí odkaz:
https://doaj.org/article/ce7fe7856504421aaaf381a0e810a653
Autor:
Stephan Niebling, Osvaldo Burastero, Jérôme Bürgi, Christian Günther, Lucas A. Defelipe, Simon Sander, Ellen Gattkowski, Raghavendra Anjanappa, Matthias Wilmanns, Sebastian Springer, Henning Tidow, María García-Alai
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Differential scanning fluorimetry (DSF) using the inherent fluorescence of proteins (nDSF) is a popular technique to evaluate thermal protein stability in different conditions (e.g. buffer, pH). In many cases, ligand binding increases therma
Externí odkaz:
https://doaj.org/article/e0885ebc8fc94564a375e92b59216b89
Autor:
Ario de Marco, Nick Berrow, Mario Lebendiker, Maria Garcia-Alai, Stefan H. Knauer, Blanca Lopez-Mendez, André Matagne, Annabel Parret, Kim Remans, Stephan Uebel, Bertrand Raynal
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-4 (2021)
Proteins and peptides are amongst the most widely used research reagents but often their quality is inadequate and can result in poor data reproducibility. Here we propose a simple set of guidelines that, when correctly applied to protein reagents sh
Externí odkaz:
https://doaj.org/article/51ce73ae195442a99d981f1a7543b04b
Autor:
Stephan Niebling, Katharina Veith, Benjamin Vollmer, Javier Lizarrondo, Osvaldo Burastero, Janina Schiller, Angelica Struve García, Philipp Lewe, Carolin Seuring, Susanne Witt, María García-Alai
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Successful sample preparation is the foundation to any structural biology technique. Membrane proteins are of particular interest as these are important targets for drug design, but also notoriously difficult to work with. For electron cryo-microscop
Externí odkaz:
https://doaj.org/article/b0f17dbc4aac4036962350cb153663d5
Autor:
Raghavendra Anjanappa, Maria Garcia-Alai, Janine-Denise Kopicki, Julia Lockhauserbäumer, Mohamed Aboelmagd, Janina Hinrichs, Ioana Maria Nemtanu, Charlotte Uetrecht, Martin Zacharias, Sebastian Springer, Rob Meijers
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Major Histocompatibility Complex (MHC) class I molecules present tightly binding peptides on the cell surface for recognition by cytotoxic T cells. Here, the authors present the crystal structures of a disulfide-stabilized human MHC class I molecule
Externí odkaz:
https://doaj.org/article/0a9d6a6f48e3448e84d9257ff4977dbc