Zobrazeno 1 - 10
of 307
pro vyhledávání: '"Maria G. Belvisi"'
Autor:
James W. Pinkerton, Silvia Preite, Antonio Piras, Dimitrios Zervas, Thomais Markou, Mark S. Freeman, Tobias Hofving, Emil Ivarsson, Sara J. Bonvini, Wayne Brailsford, Linda Yrlid, Maria G. Belvisi, Mark A. Birrell
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-10 (2024)
Abstract Background Two isoforms of Phosphoinositide 3-kinase (PI3K), p110γ and p110δ, are predominantly expressed in leukocytes and represent attractive therapeutic targets for the treatment of allergic asthma. The study aim was to assess the impa
Externí odkaz:
https://doaj.org/article/34e0cce183ac4d01b5e4f1bcb2a5c774
Autor:
Jacob M. vanLaar, Alejhandra Lei, Mary Safy‐Khan, Joachim Almquist, Graham Belfield, Karl Edman, Lisa Öberg, Bastian R. Angermann, Inken Dillmann, Pia Berntsson, Damla Etal, Ian Dainty, Carol Astbury, Maria G. Belvisi, Szilárd Nemes, Adam Platt, Susanne Prothon, Sara Samuelsson, Petter Svanberg, Christina Keen, the SEMRA study group
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 12, Pp 2494-2506 (2023)
Abstract Oral corticosteroid use is limited by side effects, some caused by off‐target actions on the mineralocorticoid receptor that disrupt electrolyte balance. AZD9567 is a selective, nonsteroidal glucocorticoid receptor modulator. The efficacy,
Externí odkaz:
https://doaj.org/article/a7401ac9a26c4a28953bd5b0830bee0b
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-4 (2022)
Abstract With prevalent global air pollution, individuals with certain genetic predispositions and sensitivities are at of higher risk of developing respiratory symptoms including chronic cough. Studies to date have relied on patient-filled questionn
Externí odkaz:
https://doaj.org/article/7e4eedf6655d48958459257723c0affd
Autor:
Ventzislava A. Hristova, Alastair Watson, Raghothama Chaerkady, Matthew S. Glover, Jodie Ackland, Bastian Angerman, Graham Belfield, Maria G. Belvisi, Hannah Burke, Doriana Cellura, Howard W. Clark, Damla Etal, Anna Freeman, Ashley I. Heinson, Sonja Hess, Michael Hühn, Emily Hall, Alex Mackay, Jens Madsen, Christopher McCrae, Daniel Muthas, Steven Novick, Kristoffer Ostridge, Lisa Öberg, Adam Platt, Anthony D. Postle, C. Mirella Spalluto, Outi Vaarala, Junmin Wang, Karl J. Staples, Tom M.A. Wilkinson, on behalf of the MICA II Study group
Publikováno v:
ERJ Open Research, Vol 9, Iss 3 (2022)
Rationale Pulmonary surfactant is vital for lung homeostasis as it reduces surface tension to prevent alveolar collapse and provides essential immune-regulatory and antipathogenic functions. Previous studies demonstrated dysregulation of some individ
Externí odkaz:
https://doaj.org/article/d0133b7993c74d2bbea08bf595e4130e
Autor:
Ryan S. Dhindsa, Johan Mattsson, Abhishek Nag, Quanli Wang, Louise V. Wain, Richard Allen, Eleanor M. Wigmore, Kristina Ibanez, Dimitrios Vitsios, Sri V. V. Deevi, Sebastian Wasilewski, Maria Karlsson, Glenda Lassi, Henric Olsson, Daniel Muthas, Susan Monkley, Alex Mackay, Lynne Murray, Simon Young, Carolina Haefliger, FinnGen Consortium, Toby M. Maher, Maria G. Belvisi, Gisli Jenkins, Philip L. Molyneaux, Adam Platt, Slavé Petrovski
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-8 (2021)
Ryan Dhindsa et al. conducted an exome-wide association study to identify a rare variant in SPDL1 as a risk factor for idiopathic pulmonary fibrosis (IPF). Their findings implicate mitotic checkpoint signalling as a new mechanism underlying IPF.
Externí odkaz:
https://doaj.org/article/5ca8ca31c47044f2a6b834855f2cbf1a
Publikováno v:
European Respiratory Review, Vol 30, Iss 159 (2021)
COPD and idiopathic pulmonary fibrosis (IPF) together represent a considerable unmet medical need, and advances in their treatment lag well behind those of other chronic conditions. Both diseases involve maladaptive repair mechanisms leading to progr
Externí odkaz:
https://doaj.org/article/fa8b8c5775c84ec8a9c3512a4ff0943b
Autor:
Maria G. Belvisi, Katie Baker, Nicole Malloy, Kristof Raemdonck, Bilel Dekkak, Michael Pieper, Anthony T. Nials, Mark A. Birrell
Publikováno v:
Respiratory Research, Vol 19, Iss 1, Pp 1-11 (2018)
Abstract Background Asthmatics that are exposed to inhaled pollutants such as cigarette smoke (CS) have increased symptom severity. Approximately 25% of adult asthmatics are thought to be active smokers and many sufferers, especially in the third wor
Externí odkaz:
https://doaj.org/article/1c92a32bcc084efe8ea4f7df5b4ae55d
Publikováno v:
Respiratory Research, Vol 18, Iss 1, Pp 1-17 (2017)
Abstract Background The incidence of asthma is increasing at an alarming rate. While the current available therapies are effective, there are associated side effects and they fail to adequately control symptoms in all patient subsets. In the search t
Externí odkaz:
https://doaj.org/article/7053e2ec9aff4bb8991d8f9796aa759f
Autor:
Joseph M. D. Rastrick, Christopher S. Stevenson, Suffwan Eltom, Megan Grace, Meirion Davies, Iain Kilty, Steven M. Evans, Manolis Pasparakis, Matthew C. Catley, Toby Lawrence, Ian M. Adcock, Maria G. Belvisi, Mark A. Birrell
Publikováno v:
PLoS ONE, Vol 8, Iss 10 (2013)
Externí odkaz:
https://doaj.org/article/2f6d4f4143eb4208b18be5ee8f012d3f
Autor:
Louise Slater, Nathan W. Bartlett, Jennifer J. Haas, Jie Zhu, Simon D. Message, Ross P. Walton, Annemarie Sykes, Samer Dahdaleh, Deborah L. Clarke, Maria G. Belvisi, Onn M. Kon, Takashi Fujita, Peter K. Jeffery, Sebastian L. Johnston, Michael R. Edwards
Publikováno v:
PLoS Pathogens, Vol 8, Iss 4 (2012)
Externí odkaz:
https://doaj.org/article/2f897645a49f443bb24094eedabdc8d6