Zobrazeno 1 - 10
of 307
pro vyhledávání: '"Maria G Belvisi"'
Autor:
James W. Pinkerton, Silvia Preite, Antonio Piras, Dimitrios Zervas, Thomais Markou, Mark S. Freeman, Tobias Hofving, Emil Ivarsson, Sara J. Bonvini, Wayne Brailsford, Linda Yrlid, Maria G. Belvisi, Mark A. Birrell
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-10 (2024)
Abstract Background Two isoforms of Phosphoinositide 3-kinase (PI3K), p110γ and p110δ, are predominantly expressed in leukocytes and represent attractive therapeutic targets for the treatment of allergic asthma. The study aim was to assess the impa
Externí odkaz:
https://doaj.org/article/34e0cce183ac4d01b5e4f1bcb2a5c774
Autor:
Suffwan Eltom, Maria G Belvisi, Christopher S Stevenson, Sarah A Maher, Eric Dubuis, Kate A Fitzgerald, Mark A Birrell
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112829 (2014)
BackgroundChronic Obstructive Pulmonary Disease (COPD) is an inflammatory airway disease often associated with cigarette smoke (CS) exposure. The disease is increasing in global prevalence and there is no effective therapy. A major step forward would
Externí odkaz:
https://doaj.org/article/452d482d9f104bab917d806b1bff3e12
Autor:
Suffwan Eltom, Nicole Dale, Kristof R G Raemdonck, Christopher S Stevenson, Robert J Snelgrove, Pradeep K Sacitharan, Chiara Recchi, Silene Wavre-Shapton, Daniel F McAuley, Cecilia O'Kane, Maria G Belvisi, Mark A Birrell
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e101087 (2014)
Infection-related exacerbations of respiratory diseases are a major health concern; thus understanding the mechanisms driving them is of paramount importance. Despite distinct inflammatory profiles and pathological differences, asthma and COPD share
Externí odkaz:
https://doaj.org/article/b6fee8ec794c40ebb8be32da0f861af9
Autor:
Joseph M D Rastrick, Christopher S Stevenson, Suffwan Eltom, Megan Grace, Meirion Davies, Iain Kilty, Steven M Evans, Manolis Pasparakis, Matthew C Catley, Toby Lawrence, Ian M Adcock, Maria G Belvisi, Mark A Birrell
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54128 (2013)
COPD is an inflammatory lung disease largely associated with exposure to cigarette smoke (CS). The mechanism by which CS leads to the pathogenesis of COPD is currently unclear; it is known however that many of the inflammatory mediators present in th
Externí odkaz:
https://doaj.org/article/8481325e846c4181964f661b9dfc338b
Autor:
Jacob M. vanLaar, Alejhandra Lei, Mary Safy‐Khan, Joachim Almquist, Graham Belfield, Karl Edman, Lisa Öberg, Bastian R. Angermann, Inken Dillmann, Pia Berntsson, Damla Etal, Ian Dainty, Carol Astbury, Maria G. Belvisi, Szilárd Nemes, Adam Platt, Susanne Prothon, Sara Samuelsson, Petter Svanberg, Christina Keen, the SEMRA study group
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 12, Pp 2494-2506 (2023)
Abstract Oral corticosteroid use is limited by side effects, some caused by off‐target actions on the mineralocorticoid receptor that disrupt electrolyte balance. AZD9567 is a selective, nonsteroidal glucocorticoid receptor modulator. The efficacy,
Externí odkaz:
https://doaj.org/article/a7401ac9a26c4a28953bd5b0830bee0b
Autor:
Suffwan Eltom, Christopher S Stevenson, Joseph Rastrick, Nicole Dale, Kristof Raemdonck, Sissie Wong, Matthew C Catley, Maria G Belvisi, Mark A Birrell
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24097 (2011)
Chronic Obstructive Pulmonary Disease (COPD) is a cigarette smoke (CS)-driven inflammatory airway disease with an increasing global prevalence. Currently there is no effective medication to stop the relentless progression of this disease. It has rece
Externí odkaz:
https://doaj.org/article/f89eb3440113435898d0242cf8b1bd40
Autor:
Louise Slater, Nathan W Bartlett, Jennifer J Haas, Jie Zhu, Simon D Message, Ross P Walton, Annemarie Sykes, Samer Dahdaleh, Deborah L Clarke, Maria G Belvisi, Onn M Kon, Takashi Fujita, Peter K Jeffery, Sebastian L Johnston, Michael R Edwards
Publikováno v:
PLoS Pathogens, Vol 6, Iss 11, p e1001178 (2010)
The relative roles of the endosomal TLR3/7/8 versus the intracellular RNA helicases RIG-I and MDA5 in viral infection is much debated. We investigated the roles of each pattern recognition receptor in rhinovirus infection using primary bronchial epit
Externí odkaz:
https://doaj.org/article/7aaa3892a9194b66b016b415e301e757
Autor:
Ventzislava A. Hristova, Alastair Watson, Raghothama Chaerkady, Matthew S. Glover, Jodie Ackland, Bastian Angerman, Graham Belfield, Maria G. Belvisi, Hannah Burke, Doriana Cellura, Howard W. Clark, Damla Etal, Anna Freeman, Ashley I Heinson, Sonja Hess, Michael Hühn, Emily Hall, Alex Mackay, Jens Madsen, Christopher McCrae, Daniel Muthas, Steven Novick, Kristoffer Ostridge, Lisa Öberg, Adam Platt, Anthony D. Postle, C. Mirella Spalluto, Outi Vaarala, Junmin Wang, Karl J. Staples, Tom M.A Wilkinson
Publikováno v:
ERJ Open Research. :00378-2022
RationalePulmonary surfactant is vital for lung homeostasis as it reduces surface tension to prevent alveolar collapse and provides essential immune-regulatory and anti-pathogenic functions. Previous studies demonstrated dysregulation of some individ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9bb1119b4ab9577c42fa13930178e3c
https://doi.org/10.1183/23120541.00378-2022
https://doi.org/10.1183/23120541.00378-2022
Autor:
Magnus Nilsson, Magdalena Rhedin, Ramon Hendrickx, Susanne Berglund, Antonio Piras, Parmis Blomgran, Anders Cavallin, Mia Collins, Göran Dahl, Bilel Dekkak, Therese Ericsson, Niklas Hagberg, Ann Aurell Holmberg, Agnes Leffler, Anders J Lundqvist, Thomais Markou, James Pinkerton, Lars Rönnblom, Stacey Siu, Vanessa Taylor, Tiiu Wennberg, Dimitrios Zervas, Arian D J Laurence, Suman Mitra, Maria G Belvisi, Mark Birrell, Annika Borde
Publikováno v:
Drug Design, Development and Therapy. 16:2901-2917
Magnus Nilsson,1 Magdalena Rhedin,2 Ramon Hendrickx,3 Susanne Berglund,1 Antonio Piras,2 Parmis Blomgran,2 Anders Cavallin,2 Mia Collins,2 Göran Dahl,4 Bilel Dekkak,5 Therese Ericsson,3 Niklas Hagberg,6 Ann Aurell Holmberg,3 Agnes Leffler,2 Anders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e0c74bc776adaba8bf5ad2a70652436
https://doi.org/10.2147/dddt.s354291
https://doi.org/10.2147/dddt.s354291
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology
Idiopathic pulmonary fibrosis is a fatal interstitial lung disease with limited therapeutic options. Current evidence suggests that IPF may be initiated by repeated epithelial injury in the distal lung followed by abnormal wound healing responses whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdd3a2f8de9c3c0351ba2e9b0c45cef8
https://doi.org/10.1165/rcmb.2020-0476tr
https://doi.org/10.1165/rcmb.2020-0476tr