Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Maria Francesca, Cassarino"'
Autor:
Francesca Pecori Giraldi, Antonella Sesta, Laura Tapella, Maria Francesca Cassarino, Luigi Castelli
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Retinoids play a pivotal role in adrenal development and differentiation. Recent clinical trials revealed therapeutic potential of both all-trans and 9-cis retinoic acid in patients with cortisol excess due to a pituitary ACTH-secreting aden
Externí odkaz:
https://doaj.org/article/5ef9d2bcf39a4ee0b8177dcff0ede382
Autor:
Francesca Pecori Giraldi, Maria Francesca Cassarino, Antonella Sesta, Giovanni Lasio, Marco Losa
Publikováno v:
Neuroendocrinology.
Introduction. The glucocorticoid receptor is pivotal to control corticotrophin (ACTH) secretion and its function is closely linked to the heat shock protein 90 (HSP90) chaperone complex. Impaired sensitivity to glucocorticoid feedback is a hallmark o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd696bc7401e7dec547e43337a2dbe26
https://doi.org/10.1159/000529710
https://doi.org/10.1159/000529710
Autor:
Maria Francesca Cassarino, Laura Tapella, Luigi Castelli, Antonella Sesta, Francesca Pecori Giraldi
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Scientific Reports
Scientific Reports
Retinoids play a pivotal role in adrenal development and differentiation. Recent clinical trials revealed therapeutic potential of both all-trans and 9-cis retinoic acid in patients with cortisol excess due to a pituitary ACTH-secreting adenoma and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::953cbdefe4b403c59d27979bea0a42cb
https://doaj.org/article/5ef9d2bcf39a4ee0b8177dcff0ede382
https://doaj.org/article/5ef9d2bcf39a4ee0b8177dcff0ede382
Autor:
Maria Francesca Cassarino, Marco Losa, Giovanni Lasio, M. R. Terreni, Alberto Giacinto Ambrogio, Antonella Sesta, Donatella Bardelli, Francesca Pecori Giraldi, Laura Libera
Publikováno v:
Neuroendocrinology. 110:119-129
Background: Somatic mutations in the ubiquitin-specific protease 8 (USP8) gene have recently been shown to occur in ACTH-secreting pituitary adenomas, thus calling attention to the ubiquitin system in corticotrope adenomas. Objectives: Assess the con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b40690b2449ee169701d0f0606d359a2
https://doi.org/10.1159/000500688
https://doi.org/10.1159/000500688
Autor:
Luigi Castelli, Antonella Sesta, Francesca Pecori Giraldi, Laura Tapella, Maria Francesca Cassarino
Publikováno v:
Endocrine Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49637e47fe5e3cdae5cdd717d2fefcca
https://doi.org/10.1530/endoabs.73.aep15
https://doi.org/10.1530/endoabs.73.aep15
Autor:
Antonella Sesta, Francesca Pecori Giraldi, Donatella Bardelli, Marco Losa, Giovanni Lasio, Laura Libera, Maria Francesca Cassarino
Publikováno v:
Journal of the Endocrine Society
Silibinin, a milk thistle extract with known hepatoprotective effects, has recently been shown to act upon tumoral corticotropes and revert the Cushingoid phenotype in an allograft mouse model (Riebold et al 2015). Silbinin is known to inhibit HSP90
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e9370c9ed4293af0bf565e8840c43cc
http://europepmc.org/articles/PMC7208688
http://europepmc.org/articles/PMC7208688
Publikováno v:
Endocrine
Purpose A large number of studies has investigated proopiomelanocortin processing in anterior pituitary corticotropes but little is known on proopiomelanocortin/ACTH degradation within these cells. The ubiquitin-proteasome system is an intracellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4b285e29f3e6bf4714db1fcec130556
https://doi.org/10.1007/s12020-018-1573-9
https://doi.org/10.1007/s12020-018-1573-9
Autor:
Antonella, Sesta, Maria Francesca, Cassarino, Mariarosa, Terreni, Alberto G, Ambrogio, Laura, Libera, Donatella, Bardelli, Giovanni, Lasio, Marco, Losa, Francesca, Pecori Giraldi
Publikováno v:
Neuroendocrinology. 110(1-2)
BACKGROUND: Somatic mutations in the ubiquitin-specific protease 8 (USP8) gene have recently been shown to occur in ACTH-secreting pituitary adenomas, thus calling attention to the ubiquitin system in corticotrope adenomas. OBJECTIVES: Assess the con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::17124d0e3cc3441b4607a81328f8c7c6
https://pubmed.ncbi.nlm.nih.gov/31280266
https://pubmed.ncbi.nlm.nih.gov/31280266
Autor:
Maria Francesca Cassarino, Francesca Pecori Giraldi, Antonella Sesta, Luigi Castelli, Laura Tapella, Francesco Cavagnini
Publikováno v:
Life Sciences. 151:277-280
AimsRetinoic acid has recently yielded promising results in the treatment of Cushing's disease, i.e., excess cortisol secretion due to a pituitary corticotropin (ACTH)-secreting adenoma. In addition to its effect on the tumoral corticotrope cell, cli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8675d22c1a7d6b4a3eed4a70a67a5b30
Autor:
Marco Losa, Mario Detomas, Maria Francesca Cassarino, Angela Pagnano, Pietro Mortini, Francesca Pecori Giraldi
Purpose: somatic mutations in the ubiquitin-specific protease 8 (USP8) gene have recently been described in patients with Cushing’s disease (CD). The aim of the study is to verify whether USP8 mutation may predict early and late outcome of pituitar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c9e2086d09223a52679034075b22f1c
