Growth hormone secretagogue receptor in dopamine neurons controls appetitive and consummatory behaviors towards high-fat diet in ad-libitum fed mice

Autor: Mario Perello, Daniela Cassano, Pablo Nicolás de Francesco, Maria Florencia Andreoli, María Paula Cornejo, Mirta Reynaldo, Guadalupe García Romero, Franco Barrile, Julieta Paola Aguggia

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

Growth hormone secretagogue receptor (GHSR), the receptor for ghrelin, is expressed in key brain nuclei that regulate food intake. The dopamine (DA) pathways have long been recognized to play key roles mediating GHSR effects on feeding behaviors. Her

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e088377bda5712d2544e226eb86d27c
https://pubmed.ncbi.nlm.nih.gov/32535402

Epigenetic Dysregulation of Dopaminergic System by Maternal Cafeteria Diet During Early Postnatal Development

Autor: Maria Florencia Andreoli, María Florencia Rossetti, Rocio Schumacher, Jorge G. Ramos, Cora Stoker, Jorgelina Varayoud, María Paula Gastiazoro, Gisela Paola Lazzarino

Dopamine is a neurotransmitter crucial for motor, motivational, and reward-related functions. Our aim was to determine the effect of a palatable maternal diet on the transcriptional regulation of dopaminergic-related genes during perinatal developmen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c8b83ffb00987271c5b0eeecb17bd9d
https://linkinghub.elsevier.com/retrieve/pii/S030645221930661X

Temporary effects of neonatal overfeeding on homeostatic control of food intake involve alterations in POMC promoter methylation in male rats

Autor: Maria Florencia Andreoli, Guillermina Canesini, Gisela Paola Lazzarino, Ana Paula García, Rocio Schumacher, Cora Stoker, Jorge G. Ramos, María Florencia Rossetti

Publikováno v: Molecular and Cellular Endocrinology. 522:111123

A small litter (SL) model was used to determine how neonatal overfeeding affects the homeostatic control of food intake in male rats at weaning and postnatal day (PND) 90. At PND4, litters were reduced to small (4 pups/dam) or normal (10 pups/dam) li

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4698d6b1f2812523e98399360f46a4c1
https://doi.org/10.1016/j.mce.2020.111123

Induction of uterine hyperplasia after cafeteria diet exposure

Autor: Maria Florencia Andreoli, Marlise Guerrero-Schimpf, María Paula Gastiazoro, Oliver Zierau, Jorgelina Varayoud, Gisela Paola Lazzarino, Jorge G. Ramos, Enrique H. Luque, Milena Durando

Our aim was to evaluate whether chronic administration of CAF affects the uterus and induces the morphological and molecular changes associated with endometrial hyperplasia. Female Wistar rats exposed to CAF from weaning for 20 weeks displayed increa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57b6ed73bf1c56fad02a2a9dabf15546
https://linkinghub.elsevier.com/retrieve/pii/S030372071830193X

Evidence supporting a role for constitutive ghrelin receptor signaling in fasting-induced hyperphagia in male mice

Autor: Alexandra Labarthe, Agustina Cabral, Maria Florencia Andreoli, Gimena Fernandez, Céline M'Kadmi, Jorge G. Ramos, Mario Perello, Virginie Tolle, Jean-Alain Fehrentz, Jacky Marie, Jacques Epelbaum

Publikováno v: Endocrinology
Endocrinology, Endocrine Society, 2018, 159 (2), pp.1021-1034. ⟨10.1210/en.2017-03101⟩
SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP

Ghrelin is a potent orexigenic peptide hormone that acts through the growth hormone secretagogue receptor (GHSR), a G protein-coupled receptor highly expressed in the hypothalamus. In vitro studies have shown that GHSR displays a high constitutive ac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::756bd34db28eabe641ff66aaf88d6079
https://academic.oup.com/endo/article-abstract/159/2/1021/4780800?redirectedFrom=fulltext