Apoptosis recognition receptors regulate skin tissue repair in mice

Autor: Olivia Justynski, Kate Bridges, Will Krause, Maria Fernanda Forni, Quan M Phan, Teresa Sandoval-Schaefer, Kristyn Carter, Diane E King, Henry C Hsia, Michael I Gazes, Steven D Vyce, Ryan R Driskell, Kathryn Miller-Jensen, Valerie Horsley

Publikováno v: eLife, Vol 12 (2023)

Apoptosis and clearance of apoptotic cells via efferocytosis are evolutionarily conserved processes that drive tissue repair. However, the mechanisms by which recognition and clearance of apoptotic cells regulate repair are not fully understood. Here

Externí odkaz: https://doaj.org/article/dbdf124a3b954f59bcd564236e200881

Caloric Restriction Promotes Structural and Metabolic Changes in the Skin

Autor: Maria Fernanda Forni, Julia Peloggia, Tárcio T. Braga, Jesús Eduardo Ortega Chinchilla, Jorge Shinohara, Carlos Arturo Navas, Niels Olsen Saraiva Camara, Alicia J. Kowaltowski

Publikováno v: Cell Reports, Vol 20, Iss 11, Pp 2678-2692 (2017)

Caloric restriction (CR) is the most effective intervention known to enhance lifespan, but its effect on the skin is poorly understood. Here, we show that CR mice display fur coat remodeling associated with an expansion of the hair follicle stem cell

Externí odkaz: https://doaj.org/article/8684be283d9f456ebd386c8f55a28933

Dynamic quality control machinery that operates across compartmental borders mediates the degradation of mammalian nuclear membrane proteins

Autor: Pei-Ling Tsai, Christopher J.F. Cameron, Maria Fernanda Forni, Renee R. Wasko, Brigitte S. Naughton, Valerie Horsley, Mark B. Gerstein, Christian Schlieker

Publikováno v: Cell Reports. 41:111675

Many human diseases are caused by mutations in nuclear envelope (NE) proteins. How protein homeostasis and disease etiology are interconnected at the NE is poorly understood. Specifically, the identity of local ubiquitin ligases that facilitate ubiqu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::680a1e673883d31d7a233547a5d1c597
https://doi.org/10.1016/j.celrep.2022.111675

Simultaneous Isolation of Three Different Stem Cell Populations from Murine Skin.

Autor: Maria Fernanda Forni, Aline Ramos Maia Lobba, Alexandre Hamilton Pereira Ferreira, Mari Cleide Sogayar

Publikováno v: PLoS ONE, Vol 10, Iss 10, p e0140143 (2015)

The skin is a rich source of readily accessible stem cells. The level of plasticity afforded by these cells is becoming increasingly important as the potential of stem cells in Cell Therapy and Regenerative Medicine continues to be explored. Several

Externí odkaz: https://doaj.org/article/b7754e13ab04414e8a19c67bbd91b3cd

An immunometabolic shift modulates cytotoxic lymphocyte activation during melanoma progression in TRPA1 channel null mice

Autor: Omar Domínguez-Amorocho, Leonardo Vinícius Monteiro de Assis, Maria Fernanda Forni, Niels Olsen Saraiva Câmara, Gabriela Sarti Kinker, Ana Maria de Lauro Castrucci, Maria Nathália Moraes

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Frontiers in Oncology, Vol 11 (2021)
Frontiers in Oncology

Melanoma skin cancer is extremely aggressive with increasing incidence and mortality. Among the emerging therapeutic targets in the treatment of cancer, the family of transient receptor potential channels (TRPs) has been reported as a possible pharma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef93d77afe8c8a01b6e5a95fda6ef22e