Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Maria Fallman"'
Autor:
Christopher von Beek, Anna Fahlgren, Petra Geiser, Maria Letizia Di Martino, Otto Lindahl, Grisna I. Prensa, Erika Mendez-Enriquez, Jens Eriksson, Jenny Hallgren, Maria Fällman, Gunnar Pejler, Mikael E. Sellin
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Mast cells localize to mucosal tissues and contribute to innate immune defense against infection. How mast cells sense, differentiate between, and respond to bacterial pathogens remains a topic of ongoing debate. Using the prototype enteropa
Externí odkaz:
https://doaj.org/article/d1cf4a9e992844f8a5cdf7afab5f5fd2
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 1 (2024)
ABSTRACT Pathogenic bacteria encounter various stressors while residing in the host. They respond through intricate mechanisms of gene expression regulation, ensuring their survival and adaptation. Understanding how bacteria adapt to different stress
Externí odkaz:
https://doaj.org/article/d51a681ce4da4b11b1688db65932140a
Autor:
Henrik Antti, Anna Fahlgren, Elin Näsström, Konstantinos Kouremenos, Jonas Sundén-Cullberg, Yongzhi Guo, Thomas Moritz, Hans Wolf-Watz, Anders Johansson, Maria Fallman
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56971 (2013)
Due to slow diagnostics, physicians must optimize antibiotic therapies based on clinical evaluation of patients without specific information on causative bacteria. We have investigated metabolomic analysis of blood for the detection of acute bacteria
Externí odkaz:
https://doaj.org/article/05ff030da23d48308edcc748abe40452
Autor:
Kemal Avican, Jehad Aldahdooh, Matteo Togninalli, A. K. M. Firoj Mahmud, Jing Tang, Karsten M. Borgwardt, Mikael Rhen, Maria Fällman
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Bacterial stress responses are potential targets for new antimicrobials. Here, Avican et al. present global transcriptomes for 32 bacterial pathogens grown under 11 stress conditions, and identify common and unique regulatory responses, as well as pr
Externí odkaz:
https://doaj.org/article/528c32ad693d42ecb0d3a057d1175df3
Autor:
Julius Semenas, Tianyan Wang, Azharuddin Sajid Syed Khaja, AKM Firoj Mahmud, Athanasios Simoulis, Thomas Grundström, Maria Fällman, Jenny L. Persson
Publikováno v:
Molecular Oncology, Vol 15, Iss 4, Pp 968-986 (2021)
Selective ERα modulator, tamoxifen, is well tolerated in a heavily pretreated castration‐resistant prostate cancer (PCa) patient cohort. However, its targeted gene network and whether expression of intratumor ERα due to androgen deprivation thera
Externí odkaz:
https://doaj.org/article/76e6e359dd224187a7177058d52aa91f
Autor:
Abebe Aseffa Negeri, Hassen Mamo, Jyoti M. Gurung, A. K. M. Firoj Mahmud, Maria Fällman, Eyasu Tigabu Seyoum, Adey Feleke Desta, Matthew S. Francis
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
The treatment of invasive Escherichia coli infections is a challenge because of the emergence and rapid spread of multidrug resistant strains. Particular problems are those strains that produce extended spectrum β-lactamases (ESBL’s). Although the
Externí odkaz:
https://doaj.org/article/4dea0eaa016f417e86ae344dd3af0581
Autor:
A. K. M. Firoj Mahmud, Kristina Nilsson, Anna Fahlgren, Roberto Navais, Rajdeep Choudhury, Kemal Avican, Maria Fällman
Publikováno v:
mSystems, Vol 5, Iss 6 (2020)
ABSTRACT RpoN, an alternative sigma factor commonly known as σ54, is implicated in persistent stages of Yersinia pseudotuberculosis infections in which genes associated with this regulator are upregulated. We here combined phenotypic and genomic ass
Externí odkaz:
https://doaj.org/article/a3a6c3d7038f4728b7349f8495a1f005
Autor:
Sofie Ekestubbe, Jeanette E Bröms, Tomas Edgren, Maria Fällman, Matthew S Francis, Ake Forsberg
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 6 (2016)
Type III secretion systems (T3SS) are dedicated to targeting anti-host effector proteins into the cytosol of the host cell to promote bacterial infection. Delivery of the effectors requires three specific translocator proteins, of which the hydrophil
Externí odkaz:
https://doaj.org/article/7b4a4e92e34545b8964089ccad79b6ed
Autor:
Kemal Avican, Anna Fahlgren, Mikael Huss, Ann Kathrin Heroven, Michael Beckstette, Petra Dersch, Maria Fällman
Publikováno v:
PLoS Pathogens, Vol 11, Iss 1, p e1004600 (2015)
We recently found that Yersinia pseudotuberculosis can be used as a model of persistent bacterial infections. We performed in vivo RNA-seq of bacteria in small cecal tissue biopsies at early and persistent stages of infection to determine strategies
Externí odkaz:
https://doaj.org/article/c0a259a2a05649788b0496d5fe9917b2
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0133298 (2015)
Microbial pathogens and host immune cells each initiate events following their interaction in an attempt to drive the outcome to their respective advantage. Here we show that the bacterial pathogen Yersinia pseudotuberculosis sustains itself on the s
Externí odkaz:
https://doaj.org/article/2b9b5e809dd64c2796ae6cb708615094