Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Maria F. Marongiu"'
Autor:
Rita D. Jores, Davide Baldera, Enrico Schirru, Sandro Muntoni, Rossano Rossino, Maria F. Manchinu, Maria F. Marongiu, Cristian A. Caria, Carlo Ripoli, Maria R. Ricciardi, Francesco Cucca, Mauro Congia
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionT cell reactivity against pancreatic autoantigens is considered one of the main contributors to the destruction of insulin-producing cells in type 1 diabetes (T1D). Over the years, peptide epitopes derived from these autoantigens have bee
Externí odkaz:
https://doaj.org/article/603db48a463a46a28bd27389e101c4ca
Autor:
Maria F. Manchinu, Maria F. Marongiu, Daniela Poddie, Carla Casu, Veronica Latini, Michela Simbula, Renzo Galanello, Paolo Moi, Antonio Cao, Susanna Porcu, Maria S. Ristaldi
Publikováno v:
Haematologica, Vol 99, Iss 1 (2014)
β-thalassemia and sickle cell disease are widespread fatal genetic diseases. None of the existing clinical treatments provides a solution for all patients. Two main strategies for treatment are currently being investigated: (i) gene transfer of a no
Externí odkaz:
https://doaj.org/article/37993b6140f64f22918b4339e0a47ccd
Autor:
Cristian Antonio Caria, Daniela Poddie, Marta Anna Kowalik, Michela Simbula, Susanna Barella, Andrea Perra, Lucia Perseu, Maria F. Marongiu, Roberto Littera, Susanna Porcu, Franca Rosa Demartis, Maria Serafina Ristaldi
Publikováno v:
British Journal of Haematology. 193:1228-1237
Sickle cell disease (SCD) is a widespread genetic disease associated with severe disability and multi-organ damage, resulting in a reduced life expectancy. None of the existing clinical treatments provide a solution for all patients. Gene therapy and
Autor:
Susanna Porcu, Dubravka Drabek, Maria F. Marongiu, Antonio Cao, Daniela Poddie, Maria Serafina Ristaldi, Ton de Wit
Publikováno v:
British Journal of Haematology, 173(5), 794-797. Wiley-Blackwell Publishing Ltd
Autor:
Pedro Ramos, Nico van Rooijen, Bart J Crielaard, Benjamin L. Ebert, Omar Abdel-Wahab, Sara Gardenghi, Saghi Ghaffari, Robert W. Grady, Carla Casu, Ritama Gupta, Ross L. Levine, Ella Guy, Laura Breda, Stefano Rivella, Maria F. Marongiu, Patricia J. Giardina
Publikováno v:
Nature medicine
Ramos, P, Casu, C, Gardenghi, S, Breda, L, Crielaard, B J, Guy, E, Marongiu, M F, Gupta, R, Levine, R L, Abdel-Wahab, O, Ebert, B L, van Rooijen, N, Ghaffari, S, Grady, R W, Giardina, P J & Rivella, S 2013, ' Macrophages support pathological erythropoiesis in polycythemia vera and beta-thalassemia ', Nature Medicine, vol. 19, no. 4, pp. 437-445 . https://doi.org/10.1038/nm.3126
Nature Medicine, 19(4), 437-445. Nature Publishing Group
Ramos, P, Casu, C, Gardenghi, S, Breda, L, Crielaard, B J, Guy, E, Marongiu, M F, Gupta, R, Levine, R L, Abdel-Wahab, O, Ebert, B L, van Rooijen, N, Ghaffari, S, Grady, R W, Giardina, P J & Rivella, S 2013, ' Macrophages support pathological erythropoiesis in polycythemia vera and beta-thalassemia ', Nature Medicine, vol. 19, no. 4, pp. 437-445 . https://doi.org/10.1038/nm.3126
Nature Medicine, 19(4), 437-445. Nature Publishing Group
Regulation of erythropoiesis is achieved by integration of distinct signals. Among these, macrophages are emerging as erythropoietin-complementary regulators of erythroid development, particularly under stress conditions. We investigated the contribu
Autor:
Antonia Follenzi, Ella Guy, Xiuli An, Laura Breda, Elizabeta Nemeth, Cindy N. Roy, Nancy C. Andrews, Patricia J. Giardina, Niva Rao, Maria F. Marongiu, Pedro Ramos, Yelena Ginzburg, Luca Melchiori, Eliezer A. Rachmilewitz, Stefano Rivella, Sara Gardenghi, Kristen Muirhead, Robert W. Grady, Narla Mohandas
Publikováno v:
Journal of Clinical Investigation. 120:4466-4477
Excessive iron absorption is one of the main features of β-thalassemia and can lead to severe morbidity and mortality. Serial analyses of β-thalassemic mice indicate that while hemoglobin levels decrease over time, the concentration of iron in the
Autor:
Nancy C. Andrews, Sara Gardenghi, Gideon Rechavi, Robert W. Grady, Laura Breda, Eliezer A. Rachmilewitz, Amy Chadburn, Ninette Amariglio, Pedro Ramos, Diedra M. Wrighting, William Breuer, Z. Ioav Cabantchik, Yi Fang Liu, Ella Guy, Stefano Rivella, Patricia J. Giardina, Maria F. Marongiu, Maria de Sousa
Publikováno v:
Blood. 109:5027-5035
Progressive iron overload is the most salient and ultimately fatal complication of β-thalassemia. However, little is known about the relationship among ineffective erythropoiesis (IE), the role of iron-regulatory genes, and tissue iron distribution
Autor:
Antonio Cao, Maria Serafina Ristaldi, Maria Francesca Manchinu, Maria F. Marongiu, Paolo Moi, Michela Simbula, Daniela Poddie, Veronica Latini, Renzo Galanello, Susanna Porcu, Carla Casu
Publikováno v:
Haematologica. 99(1)
β-thalassemia and sickle cell disease are widespread fatal genetic diseases. None of the existing clinical treatments provides a solution for all patients. Two main strategies for treatment are currently being investigated: (i) gene transfer of a no
Autor:
Manuela Badiali, Maria F. Marongiu, Valeria Sogos, Adele Sanna, Maria Francesca Manchinu, Veronica Latini, Carla Casu, Maria Serafina Ristaldi, Francesca Crobu, F. Scintu, Susanna Porcu
Publikováno v:
Molecular biology reports. 39(4)
The adult bone marrow contains a subset of non-haematopoietic cells referred to as bone marrow mesenchymal stem cells (BMSCs). Mesenchymal stem cells (MSCs) have attracted immense research interest in the field of regenerative medicine due to their a
Autor:
Maria F. Marongiu, Marc Memmi, Maria Serafina Ristaldi, L. Vacca, Veronica Latini, Giuseppe Vona, Laurent Varesi
Publikováno v:
Human biology. 75(6)
The distribution of beta-globin cluster haplotypes has been studied in the populations of Corsica (France) and Sardinia (Italy). The analysis was carried out using five restriction fragment length polymorphism markers on chromosome 11 inside the beta