Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Maria F. Gonzalez-Rimbau"'
Publikováno v:
Proceedings of the National Academy of Sciences. 106:5159-5164
Defective genome maintenance mechanisms, involving DNA repair and cell-cycle checkpoint pathways, initiate genetic instability in many sporadic and hereditary cancers. The DNA damage effector Checkpoint kinase 1 (Chk1) is a critical component of DNA
Autor:
Maria F. Gonzalez-Rimbau, Monique Rijnkels, Alejandro Contreras, Jeffrey M. Rosen, Melanie R. Ginger, Jonathan Miller, Amy N. Shore
Publikováno v:
Proceedings of the National Academy of Sciences. 103:5781-5786
PINC is a large, alternatively spliced, developmentally regulated, noncoding RNA expressed in the regressed terminal ductal lobular unit-like structures of the parous mammary gland. Previous studies have shown that this population of cells possesses
Publikováno v:
Molecular Endocrinology. 15:1993-2009
Epidemiological studies have consistently shown that an early full-term pregnancy is protective against breast cancer. We hypothesize that the hormonal milieu that is present during pregnancy results in persistent changes in the pattern of gene expre
Autor:
Christopher A. Seid, Jenny M. George, Maria F. Gonzalez-Rimbau, Venkatesh Govindarajan, Craig R. Tomlinson, Ravi K. Ramachandran, Constantin N. Flytzanis
Publikováno v:
Nucleic Acids Research. 25:3175-3182
The extracellular matrix (ECM) has been shown to play an important role in development and tissue-specific gene expression, yet the mechanism by which genes receive signals from the ECM is poorly understood. The aboral ectoderm-specific LpS1-alpha an
Autor:
Antonia Vlahou, Weiye Wang, Athula H. Wikramanayake, Maria F. Gonzalez-Rimbau, Constantin N. Flytzanis, William H. Klein
Publikováno v:
Mechanisms of Development. 60(2):185-195
All endodermal and mesenchymal cells of the sea urchin embryo descend from the vegetal plate, a thickened epithelium of approximately 50 cells arising at the early blastula stage. Cell types that derive from the vegetal plate are specified conditiona
Autor:
Constantin N. Flytzanis, Elizabeth A. Bogosian, Christina C. Niemeyer, Naidi Xu, Maria F. Gonzalez-Rimbau
Publikováno v:
Mechanisms of development. 60(2)
The distal region of the S. purpuratus actin CyIIIb gene, between −400 and −1400 nucleotides, contains at least three distinct cis-acting elements (C1R, C1L and E1) which are necessary for correct expression of fusion reporter genes in transgenic
Publikováno v:
Scopus-Elsevier
The SpCOUP-TF gene is a highly conserved sea urchin homologue of the vertebrate COUP-TFs and the Drosophila seven up subfamily of transcription factors, which are members of the orphan steroid hormone receptors. Whole-mount in situ hybridization expe