Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Maria F. Fernandes"'
Autor:
Maria F. Fernandes, Juan J. Aristizabal-Henao, Phillip M. Marvyn, Iman M'Hiri, Meghan A. Wiens, Monica Hoang, Manuel Sebastian, Renato Nachbar, Philippe St-Pierre, Kalsha Diaguarachchige De Silva, Geoffrey A. Wood, Jamie W. Joseph, Christine A. Doucette, André Marette, Ken D. Stark, Robin E. Duncan
Publikováno v:
Molecular Metabolism, Vol 81, Iss , Pp 101887- (2024)
Objective: Lipotoxic injury from renal lipid accumulation in obesity and type 2 diabetes (T2D) is implicated in associated kidney damage. However, models examining effects of renal ectopic lipid accumulation independent of obesity or T2D are lacking.
Externí odkaz:
https://doaj.org/article/8c9b9df421da488caebe865e8aca19a9
Autor:
John Z. Chan, Maria F. Fernandes, Klaudia E. Steckel, Ryan M. Bradley, Ashkan Hashemi, Mishi R. Groh, German Sciaini, Ken D. Stark, Robin E. Duncan
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Barth syndrome (BTHS) is caused by mutations in the TAZ gene encoding the cardiolipin remodeling enzyme, Tafazzin. The study objective was to quantitatively examine growth characteristics and mitochondrial morphology of transformed lymphobla
Externí odkaz:
https://doaj.org/article/e981dfcddf044e0a919325c2b0c41a58
Autor:
RENATA F. MENDES, PAULA M.Q. BELLOZI, JÉSSICA L. MOTA CONEGUNDES, MARIA F. FERNANDES, NÍCOLAS C.C. PINTO, JOSIANE M. DA SILVA, JULIANA C. DA COSTA, LUCIANA M. CHEDIER, ALBERTO C.P. DIAS, ELITA SCIO
Publikováno v:
Anais da Academia Brasileira de Ciências, Vol 93, Iss suppl 4 (2021)
Abstract Syzygium malaccense is popularly used to treat inflammation and pain-related ailments. The species was assessed regarding its antioxidant, antiglycant, anti-inflammatory, including anti-neuroinflammatory, and antinociceptive activities. Diff
Externí odkaz:
https://doaj.org/article/f1cf78a43b15451da962fba5cba48600
Autor:
Michelle V. Tomczewski, Robin E. Duncan, Maria F. Fernandes, Ken D. Stark, Kalsha H. Diaguarachchige De Silva, Kristin A. Marks
Publikováno v:
Biochemistry and Cell Biology. 99:725-734
Delta-6-desaturase (D6D) activity is deficient in MCF-7 and other cancer cell lines, but it is not explained by FADS2 gene mutations. This deficient activity was not ameliorated by induction of the FADS2 gene; therefore, we hypothesized that some of
Publikováno v:
Brain, Behavior, and Immunity. 95:391-400
The central signaling actions of cytokines are mediated by signal transducer and activator of transcription (STAT3). STAT3 activation plays a pivotal role in the behavioral responses to the adiposity hormone leptin, including in midbrain dopamine (DA
Autor:
Kristin A, Marks, Maria F, Fernandes, Kalsha H, Diaguarachchige De Silva, Michelle V, Tomczewski, Ken D, Stark, Robin E, Duncan
Publikováno v:
Biochemistry and cell biology = Biochimie et biologie cellulaire. 99(6)
Delta-6-desaturase (D6D) activity is deficient in MCF-7 and other cancer cell lines, but it is not explained by
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 8; Pages: 4163
Glucagon-like peptide-1 (GLP-1) potentiates glucose-stimulated insulin secretion (GSIS). While dozens of compounds stimulate GLP-1 secretion, few inhibit. Reduced GLP-1 secretion and impaired GSIS occur in chronic inflammation. Lysophosphatidic acids
Publikováno v:
Lipids. 54(8)
Lysophosphatidic acids (lysoPtdOH) are involved in several physiological processes including cell proliferation, inflammation, and glucose metabolism. However, measuring lysoPtdOH is challenging due to inadequate extraction techniques, poor chromatog
Autor:
Alexandre Fisette, Christine Des Rosiers, Caroline Daneault, Stephanie Fulton, Stéphanie Auguste, Sandeep Sharma, Maria F. Fernandes
Publikováno v:
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 64
Insufficient dietary intake of essential omega-3 polyunsaturated fatty acids (N-3), especially during critical stages of development, is well-associated with negative neurological and metabolic consequences. The increased availability and intake of f
Publikováno v:
Canadian Journal of Diabetes. 37:260-268
The propensity to select and consume palatable nutrients is strongly influenced by the rewarding effects of food. Neural processes integrating reward, emotional states and decision-making can supersede satiety signals to promote excessive caloric int