Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Maria F. Czyzyk Krzeska"'
Autor:
Maria F. Czyzyk-Krzeska, Jarek Meller, Julio A. Landero Figueroa, David R. Plas, John T. Cunningham
Publikováno v:
Molecular & Cellular Oncology, Vol 8, Iss 2 (2021)
Tobacco smoking (TS) results in reprogramming of major metabolic pathways, including glycolysis, the citric acid (TCA) cycle, oxidative phosphorylation, and metabolism of aspartate, glutamate and glutamine in clear cell renal cell carcinoma (ccRCC).
Externí odkaz:
https://doaj.org/article/ec88ba9d0f424b73a36d79f03d98bf58
Autor:
Maria F. Czyzyk-Krzeska, Jarek Meller, Rachel M. Sheridan, Linda Levin, Enas Alshaikh, Jacek Biesiada, Prabhat Bastola, Aygun Mamedova, Olga Mikhaylova, Ying Yi
Supplementary Figures 1-7, Tables 1-4 from von Hippel-Lindau–Dependent Patterns of RNA Polymerase II Hydroxylation in Human Renal Clear Cell Carcinomas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::807f0a8a61f6a4175a7fb208239ab4e2
https://doi.org/10.1158/1078-0432.22442973
https://doi.org/10.1158/1078-0432.22442973
Autor:
Maria F. Czyzyk-Krzeska, Jarek Meller, Rachel M. Sheridan, Linda Levin, Enas Alshaikh, Jacek Biesiada, Prabhat Bastola, Aygun Mamedova, Olga Mikhaylova, Ying Yi
Purpose: We have previously shown that von Hippel-Lindau (VHL) regulates ubiquitylation and proline 1465 hydroxylation of the large subunit of RNA polymerase II, Rpb1, in human renal clear cell carcinoma (RCC) cell lines. Here, our goal was to determ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79ebe189c52eb4d16dddd9e2f6fc28e0
https://doi.org/10.1158/1078-0432.c.6519591
https://doi.org/10.1158/1078-0432.c.6519591
Autor:
Maria F. Czyzyk-Krzeska, Julio A. Landero Figueroa, Shuchi Gulati, John T. Cunningham, Jarek Meller, Behrouz ShamsaeI, Bhargav Vemuri, David R. Plas
Publikováno v:
Genes, Vol 12, Iss 3, p 388 (2021)
The promise of personalized medicine is a therapeutic advance where tumor signatures obtained from different omics platforms, such as genomics, transcriptomics, proteomics, and metabolomics, in addition to environmental factors including metals and m
Externí odkaz:
https://doaj.org/article/0650cc5ed5eb419eb3e59e95d453f5bc
Autor:
Rita Verma, Parul Aggarwal, Megan E. Bischoff, James Reigle, Dina Secic, Collin Wetzel, Katherine VandenHeuvel, Jacek Biesiada, Birgit Ehmer, Julio A. Landero Figueroa, David R. Plas, Mario Medvedovic, Jarek Meller, Maria F. Czyzyk-Krzeska
Publikováno v:
Journal of Biological Chemistry. 299:104663
Autor:
Rita Verma, Parul Aggarwal, James Reigle, Dina Secic, Collin Wetzel, Megan E. Bischoff, Katherine VandenHeuvel, Jacek Biesiada, Birgit Ehmer, Julio A. Landero Figueroa, David R. Plas, Mario Medvedovic, Jarek Meller, Maria F. Czyzyk-Krzeska
MAP1LC3C (LC3C) is a member of the microtubule associated family of proteins that are essential in the formation of autophagosomes and lysosomal degradation of cargo. LC3C has tumor suppressing activity and its expression is dependent on kidney cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf0720b4e561045bb2fb77634b9f3b3d
https://doi.org/10.1101/2022.05.11.491473
https://doi.org/10.1101/2022.05.11.491473
Autor:
Shuchi Gulati, Behrouz Shamsaei, Bhargav Vemuri, Juechen Yang, Dina Secic, Megan Bischoff, Julio A Landero Figueroa, David R. Plas, Tom Cunningham, Jarek Meller, Maria F. Czyzyk-Krzeska
Publikováno v:
Journal of Clinical Oncology. 41:722-722
722 Background: Previous large scale genomic studies have described somatic alterations that affect tumor progression. However, metabolic and immune pathway changes that occur with advancing disease stage are not well characterized. Herein, we perfor
Autor:
Michael J Newbold, Anurag Paul, Jun-Lin Guan, Megan E Bischoff, Jarek Meller, Nicholas J Talbot, Adam D Price, Yuanwei Zang, Maria F. Czyzyk-Krzeska, Birgit Ehmer, Johnson Chu, David R. Plas
Publikováno v:
The Journal of Cell Biology
The work identifies a noncanonical autophagic program mediated by the hominid-specific LC3C paralog functioning downstream from the von Hippel–Lindau tumor suppressor. The program targets for lysosomal degradation postdivision midbodies in a mechan
Autor:
John T. Cunningham, Maria F. Czyzyk-Krzeska, Jarek Meller, Julio A. Landero Figueroa, David R. Plas
Publikováno v:
Mol Cell Oncol
Tobacco smoking (TS) results in reprogramming of major metabolic pathways, including glycolysis, the citric acid (TCA) cycle, oxidative phosphorylation, and metabolism of aspartate, glutamate and glutamine in clear cell renal cell carcinoma (ccRCC).
Autor:
Megan E. Bischoff, Yuanwei Zang, Johnson Chou, Adam D. Price, Birgit Ehmer, Nicholas J. Talbot, Michael J. Newbold, Anurag Paul, Jun-Lin Guan, David R. Plas, Jarek Meller, Maria F. Czyzyk-Krzeska
LC3s are canonical proteins necessary for the formation of autophagosomes. We have previously established that two paralogs, LC3B and LC3C, have opposite activities in renal cancer, with LC3B playing oncogenic role and LC3C tumor suppressing role. LC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f3b96edef35831b2e84293daab1795e
https://doi.org/10.1101/2021.02.19.431861
https://doi.org/10.1101/2021.02.19.431861