Scaled up and telescoped synthesis of propofol under continuous-flow conditions

Autor: Guilherme M. Martins, Maria F. A. Magalhães, Timothy J. Brocksom, Vanderlei S. Bagnato, Kleber T. de Oliveira

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Herein we report a machine-assisted and scaled-up synthesis of propofol, a short-acting drug used in procedural sedation, which is extensively in demand during this COVID-19 pandemic. The continuous-flow protocol proved to be efficient, with great po

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4759d9024385208f3d17ceded5057531
https://pubmed.ncbi.nlm.nih.gov/35873601